Prevalence of liver cirrhosis based on the metabolic health and weight criteria: Report from the Korea National Health and Nutrition Examination Survey (KNHANES) data analysis

Mun, Hyukjin; So, Eun Sun

doi:10.1016/j.aohep.2022.100721

Cited by 2 publications

(1 citation statement)

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“…In a recent Spanish population survey on the prevalence of NASH-related liver fibrosis, the prevalence of cirrhosis in the current biopsy-proven NASH cohort (a total of 501 patients from 2015-2020) was 0.70% (95%CI 0.10%-4.95%)[ 17 ]. A survey analyzing the Korea National Health and Nutrition Examination Survey (KNHANES) between 2015 and 2019 reported prevalence rates of cirrhosis in metabolically healthy obesity and metabolically unhealthy obesity populations of 0.5% and 0.4%, respectively[ 18 ]. In the TARGET-NASH study conducted from August 2016 to March 2019, researchers revealed that lean participants had a lower prevalence of cirrhosis (22.6% vs 40.2% of nonlean participants), with almost half of the lean subjects being Asian.…”

Section: Current Epidemiology Of Liver Cirrhosismentioning

confidence: 99%

Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions

Liu¹,

Chen²

2022

World J Gastroenterol

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Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date epidemiological features of cirrhosis and its complications. Recent epidemiological studies reported an increase in the prevalence of cirrhosis in 2017 compared to in 1990 in both men and women, with 5.2 million cases of cirrhosis and chronic liver disease occurring in 2017. Cirrhosis caused 1.48 million deaths in 2019, an increase of 8.1% compared to 2017. Disability-adjusted life-years due to cirrhosis ranked 16th among all diseases and 7th in people aged 50-74 years in 2019. The global burden of hepatitis B virus and hepatitis C virus-associated cirrhosis is decreasing, while the burden of cirrhosis due to alcohol and nonalcoholic fatty liver disease (NAFLD) is increasing rapidly. We described the current epidemiology of the major complications of cirrhosis, including ascites, variceal bleeding, hepatic encephalopathy, renal disorders, and infections. We also summarized the epidemiology of hepatocellular carcinoma in patients with cirrhosis. In the future, NAFLD-related cirrhosis will likely become more common due to the prevalence of metabolic diseases such as obesity and diabetes, and the prevalence of alcohol-induced cirrhosis is increasing. This altered epidemiology should be clinically noted, and relevant interventions should be undertaken.

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Section: Current Epidemiology Of Liver Cirrhosismentioning

confidence: 99%