Prevalence of lupus nephritis in diagnosed patients of systemic lupus erythematosis (SLE) presenting to nephrology division, Khyber teaching hospital Peshawar

Abstract

Objective: To determine the prevalence of lupus nephritis in patients diagnosed with systemic lupus erythematosis (SLE). Settings: This observational study was conducted at the department of nephrology, Khyber Teaching Hospital, Peshawar Pakistan. Participants were enrolled from 1st January 2023 to 31st March 2023. Materials and methods: Patients diagnosed with SLE were enrolled. SLE was confirmed based American college of rheumatology criteria for SLE (positive ANA ≥1:80 and clinical score 10 or more). Lupus nephritis was confirmed when serum creatinine was more than 1.5mg/dl and urinary protein loss more than 0.5gm/day. Results: A total of 109 patients were enrolled. Mean age of the patients was 29.80 ± 5.245 years. 68 participants (62.4%) were female. Lupus nephritis was observed in 56 patients (51.4%). Correlation of lupus nephritis showed significant association with age and gender of the patient. Conclusion: Lupus nephritis is fairly common in patients with SLE in our population. Young female patients are more likely having it.