Prevalence of major eye diseases and causes of visual impairment in the adult Finnish population: a nationwide population‐based survey

Laitinen, Arja; Laatikainen, Leila; Härkänen, Tommi; Koskinen, Seppo; Reunanen, Antti; Aromaa, Arpo

doi:10.1111/j.1755-3768.2009.01566.x

Cited by 63 publications

(72 citation statements)

References 59 publications

(133 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, many of our other findings are also in agreement with previous studies, e.g. our overall cataract prevalence is comparable to a recent population-based study in Finland [17], and the risk of sympathomimetic drugs or inhaled glucocorticoids for cataractogenesis is well known (for a recent review see [18]). The preferred sequence of cataract formation followed by AMD is also in line with previous observations of an association of cataract surgery with late AMD [19].…”

Section: Discussionsupporting

confidence: 93%

Common eye diseases in older adults of southern Germany: results from the KORA-Age study

et al. 2016

View full text Add to dashboard Cite

Purposea population-based study in the region of Augsburg (Germany, KORA) was used to identify the prevalence of eye diseases and their risk factors in a sample of aged individuals.Methodsdata originated from the KORA-Age study collected in 2012 and 822 participants (49.6% women, 50.4% men, aged 68–96 years) were asked standardised questions about eye diseases. Positive answers were validated and specified by treating ophthalmologists. Additional information came from laboratory data. Polymorphic markers were tested for candidate genes.Resultswe received validations and specifications for 339 participants. The most frequent eye diseases were cataracts (299 cases, 36%), dry eyes (120 cases, 15%), glaucoma (72 cases, 9%) and age-related macular degeneration (AMD) (68 cases, 8%). Almost all participants suffering from glaucoma or from AMD also had cataracts. Cataract surgery was associated with diabetes (in men; OR = 2.24; 95% confidence interval [CI] 1.11–4.53; P = 0.025) and smoking (in women; OR = 6.77; CI 1.62–28.35; P = 0.009). In men, treatments in airway diseases was associated with cataracts (glucocorticoids: OR = 5.29, CI 1.20–23.37; P = 0.028; sympathomimetics: OR = 4.57, CI 1.39–15.00; P = 0.012). Polymorphisms in two genes were associated with AMD (ARMS2: OR = 2.28, CI 1.48–3.51; P = 0.005; CFH: OR = 2.03, CI 1.35–3.06; P = 0.010).Conclusioncombinations of eye diseases were frequent at old age. The importance of classical risk factors like diabetes, hypertension and airway diseases decreased either due to a survivor bias leaving healthier survivors in the older age group, or due to an increased influence of other up to now unknown risk factors.

show abstract

Section: Discussionsupporting

confidence: 93%

Common eye diseases in older adults of southern Germany: results from the KORA-Age study

et al. 2016

View full text Add to dashboard Cite

show abstract

“…These observations have been supported by several other studies that have linked lutein and zeaxanthin concentrations to the reduction of cataracts in North Indian population [82], in older American women [83] and in Australian population [84]. Recent studies also reported the prevalence of major eye diseases and showed that high plasma concentrations of lutein and zeaxanthin reduced the risk of age-related cataract in the elderly Finnish population by about 41% [85,86]. Studies involving older Europeans from Norway, Estonia, United Kingdom, France, Italy, Greece and Spain have reported high AMD prevalence (4% to 12%) depending on age [87].…”

Section: Lutein and Zeaxanthin Carotenoidssupporting

confidence: 63%

Dietary Sources of Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health

Abdel-Aal

Akhtar

Zaheer³

et al. 2013

Nutrients

423

212

View full text Add to dashboard Cite

The eye is a major sensory organ that requires special care for a healthy and productive lifestyle. Numerous studies have identified lutein and zeaxanthin to be essential components for eye health. Lutein and zeaxanthin are carotenoid pigments that impart yellow or orange color to various common foods such as cantaloupe, pasta, corn, carrots, orange/yellow peppers, fish, salmon and eggs. Their role in human health, in particular the health of the eye, is well established from epidemiological, clinical and interventional studies. They constitute the main pigments found in the yellow spot of the human retina which protect the macula from damage by blue light, improve visual acuity and scavenge harmful reactive oxygen species. They have also been linked with reduced risk of age-related macular degeneration (AMD) and cataracts. Research over the past decade has focused on the development of carotenoid-rich foods to boost their intake especially in the elderly population. The aim of this article is to review recent scientific evidences supporting the benefits of lutein and zexanthin in preventing the onset of two major age-related eye diseases with diets rich in these carotenoids. The review also lists major dietary sources of lutein and zeaxanthin and refers to newly developed foods, daily intake, bioavailability and physiological effects in relation to eye health. Examples of the newly developed high-lutein functional foods are also underlined.

show abstract

“…The prevalence is reported to be 3.5–40 % depending on age for AMD, 3.3–14 % for glaucoma, and 4.4–20.9 % for diabetic retinopathy [221]. The prevalence for cataract increases with age and is over 40 % in subjects older than 75 years [222–224]. …”

Section: Judgement Of the Evidence Regarding Individual Diseasesmentioning

confidence: 99%

Critical review: vegetables and fruit in the prevention of chronic diseases

Bechthold²,

et al. 2012

View full text Add to dashboard Cite

Background Vegetables and fruit provide a significant part of human nutrition, as they are important sources of nutrients, dietary fibre, and phytochemicals. However, it is uncertain whether the risk of certain chronic diseases can be reduced by increased consumption of vegetables or fruit by the general public, and what strength of evidence has to be allocated to such an association. Methods Therefore, a comprehensive analysis of the studies available in the literature and the respective study results has been performed and evaluated regarding obesity, type 2 diabetes mellitus, hypertension, coronary heart disease (CHD), stroke, cancer, chronic inflammatory bowel disease (IBD), rheumatoid arthritis (RA), chronic obstructive pulmonary disease (COPD), asthma, osteoporosis, eye diseases, and dementia. For judgement, the strength of evidence for a risk association, the level of evidence, and the number of studies were considered, the quality of the studies and their estimated relevance based on study design and size. Results For hypertension, CHD, and stroke, there is convincing evidence that increasing the consumption of vegetables and fruit reduces the risk of disease. There is probable evidence that the risk of cancer in general is inversely associated with the consumption of vegetables and fruit. In addition, there is possible evidence that an increased consumption of vegetables and fruit may prevent body weight gain. As overweight is the most important risk factor for type 2 diabetes mellitus, an increased consumption of vegetables and fruit therefore might indirectly reduces the incidence of type 2 diabetes mellitus. Independent of overweight, there is probable evidence that there is no influence of increased consumption on the risk of type 2 diabetes mellitus. There is possible evidence that increasing the consumption of vegetables and fruit lowers the risk of certain eye diseases, dementia and the risk of osteoporosis. Likewise, current data on asthma, COPD, and RA indicate that an increase in vegetable and fruit consumption may contribute to the prevention of these diseases. For IBD, glaucoma, and diabetic retinopathy, there was insufficient evidence regarding an association with the consumption of vegetables and fruit. Conclusions This critical review on the associations between the intake of vegetables and fruit and the risk of several chronic diseases shows that a high daily intake of these foods promotes health. Therefore, from a scientific point of view, national campaigns to increase vegetable and fruit consumption are justified. The promotion of vegetable and fruit consumption by nutrition and health policies is a preferable strategy to decrease the burden of several chronic diseases in Western societies.

show abstract

Prevalence of major eye diseases and causes of visual impairment in the adult Finnish population: a nationwide population‐based survey

Cited by 63 publications

References 59 publications

Common eye diseases in older adults of southern Germany: results from the KORA-Age study

Common eye diseases in older adults of southern Germany: results from the KORA-Age study

Dietary Sources of Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health

Critical review: vegetables and fruit in the prevention of chronic diseases

Contact Info

Product

Resources

About