Prevalence of Male Genital Tuberculosis in Indian Infertile Couples and Its Correlation with Female Genital Tuberculosis

Abstract

Objectives To study the prevalence of male and female genital tuberculosis in Indian infertile couples as detected by semen polymerase chain reaction (PCR) and endometrial PCR and to study the correlation of semen TB PCR with endometrial TB PCR of sexual partner. Design Noncomparative retrospective observational series. Patients A total of 100 couples presenting with infertility at clinic were enrolled after obtaining informed consent. Interventions All couples were tested for mycobacterium tuberculosis (MTB) by nested PCR on the semen and the endometrial sample. The results of PCR of sexual partners were mutually correlated. Results Out of 108 couples, 56 males and 52 females had positive PCR in the sample of semen and the endometrium. Also, 30 couples simultaneously had both semen PCR and endometrial PCR positive. Conclusion Addition of PCR tests to the routine clinical and laboratory assessments may add to the detection of subclinical urogenital infection and the timely evaluation of the asymptomatic partner of the infected person can improve the early detection of a silent but potentially devastating infection. How to cite this article Baxi A, Neema H, Kadi P, Baxi D, Kaushal M. Prevalence of Male Genital Tuberculosis in Indian Infertile Couples and Its Correlation with Female Genital Tuberculosis. J South Asian Feder Obst Gynae 2016;8(1):13-15.

Genital Tuberculosis: Myriad Presentations and Clinical Scenarios

“…In cases presenting with infertility alone without associated symptoms, classifying them as high risk for tuberculosis may be considered. 10 A thorough detailed history alone is sufficient for screening and should be included in routine gynecological history taking, especially in an Indian setting. This would also reduce the need for operative interventions in the patient, given that they are mostly young adults and often desirous of conception.…”