Prevalence of maternal group B streptococcus colonization and vertical transmission in low-risk women in a single institute

Yang, Mingjie; Sun, Pi-Lin; Wen, Kuo-Chang; Chao, Kuan-Chong; Chang, Wen-Hsun; Chen, Chih-Yao; Wang, Peng-Hui

doi:10.1016/j.jcma.2011.10.011

Cited by 25 publications

(21 citation statements)

References 27 publications

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“…[15][16][17] In this study prevalence of Group-B Streptococcus colonization was found to be more in women with age greater than 30 years of age. A study from Trinidad by Orrett FA et al showed a significant trend of increasing prevalence with increasing age.…”

Section: Discussionmentioning

confidence: 85%

Prevalence and risk factors for group B streptococcal colonization in pregnant women in northern India

Khatoon¹,

Nigam

Sharma

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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Section: Discussionmentioning

confidence: 85%

Prevalence and risk factors for group B streptococcal colonization in pregnant women in northern India

Khatoon¹,

Nigam

Sharma

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…Maternal factors associated with early streptococcal invasive disease in neonates are delivery before 37 weeks gestation, premature rupture of membrane more than 18 hours and intrapartum fever (2). There are different reports on GBS colonization in pregnant woman from Iran (22.7%) (3) (11.2%) (4) 10.2% (5) 3% (6) and other regions such as 20% in Taiwan (7) 15.3% in Lithuania (8) and (6.2%) in China (9), this difference might be resulted from the number of partners and sexual habits in different cultures. Studies on neonatal colonization in Iran show different results.…”

Section: Introductionmentioning

confidence: 99%

Estimation of Group B Streptococcus Colonization in High-Risk Neonates by PCR and Standard Culture

Shirvani

Shahrochi

Radfar

et al. 2014

Arch Pediatr Infect Dis

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Background: Group B Streptococcus (GBS) (Streptococcus agalactiae) is the leading cause of morbidity and mortality of newborn infants considered a leading factor causing septicemia after birth. The standard method for the diagnosis of GBS colonization is culture in a selective medium, but PCR has a high sensitivity and specificity. Objectives: The goal of this study was to estimate the colonization of GBS in rectum of neonates of high-risk mothers by culture and PCR method. Patients and Methods: Samples were taken from rectal mucosa of 154 neonatesof high-risk mothers for GBS by swabs. Samples were tested by standard culture using Todd Hewitt broth and blood agar and also by PCR using primers specific for cfb gene. Results: Of 154 neonates, Culture identified 17 (11%) neonates as colonized by GBS; and the PCR assay could identify 27 (17%) neonates with positive results for GBS. Mothers age range was 17-40 years (mean = 26.1 ± 5.1). Maternal age was significantly lower in PCR positive group (P = 0.038) and in culture positive group (P = 0.015). Using culture as the gold standard, sensitivity, NPV, specificity, and PPV of PCR were 100%, 100%, 92%, and 62%, respectively. The time required for PCR assay and culture were 2hours and 36hours, respectively. Conclusions: This study showed that the incidence of GBS in Iranian high-risk neonates is high, so we strongly recommend screening of high-risk neonates for detection of GBS.

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“…The main site for colonization of these bacteria are rectum and the vagina. Furthermore, it has been proved that the colonization in these areas is considered as a risk factor for pregnant and newborn further infection [1]. The infection by GBS in pregnant women causes bacteremia, endometritis and chorioamnionitis.…”

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confidence: 99%

Study of Some Virulence Factor and Detection of Sortase Enzymes A and Cov R/S of Streptococcus Agalactiae by PCR

2018

QJPS

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Abstract:This study included 100 pregnant and non-pregnant patients infected with vaginitis who were attended the hospital of maternity and children in Babylon province from January to May 2016. Only 25 isolates of Streptococcus agalactiae (GBS) were isolates.Sortase A enzyme were detected by using specific primer for PCR techniques and also found that all GBS strain have sortase A enzyme, so this enzyme is consider as housekeeping enzyme.Moreover, specific PCR primers were used for detection of CovR/S enzymes. It was found that CovR/S was observed only in tow isolates of Group B streptococcus GBS strains.The isolates have been examined to chick their ability to produce colonization factor antigens type1 (CFA/I) . The finding showed that they revealed the ability to produce CFA/1 in the existence of Dmannose and Vancomysin. Also, the isolates, have the ability to produce CFA/1 in the existence of Dmannose without Vancomysin.The capability of GBS isolates to produce Hemolysin in the presence of Vancomysin were studied. It was found that there was no hemolysis in the presence of Vancomysin (except for one isolate), this will give good sign for this antibiotic to reduce the ability of this bacteria to obtain iron from environment.Physiology Classification QR1-502-75-9905

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Prevalence of maternal group B streptococcus colonization and vertical transmission in low-risk women in a single institute

Abstract: Although the positive rate of GBS culture was lower in asymptomatic low-risk pregnant women, the possibility of vertical transmission might be high. This finding is worthy of further investigation.

Cited by 25 publications

References 27 publications

Prevalence and risk factors for group B streptococcal colonization in pregnant women in northern India

Prevalence and risk factors for group B streptococcal colonization in pregnant women in northern India

Estimation of Group B Streptococcus Colonization in High-Risk Neonates by PCR and Standard Culture

Study of Some Virulence Factor and Detection of Sortase Enzymes A and Cov R/S of Streptococcus Agalactiae by PCR

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