Prevalence of metabolic syndrome among Asian Indian subjects with elevated intermediate glucose response during OGTT

Viswanathan, Vijay; Kumpatla, Satyavani; Michael, Clementina; Tilak, Priyanka

doi:10.1016/j.diabres.2008.10.008

Cited by 5 publications

(3 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 14 ] A study on early glucose tolerance (early glucose intolerance [EGI] defined as 1HrPG ≥160 mg/dl and 2HrPG ≥140 and <200 mg/dl) in the Asian-Indian population revealed that the prevalence of MS was significantly higher in EGI individuals compared to NGT, 36.1% versus 27.9%. [ 23 ] Our study confirms these findings.…”

Section: Discussionsupporting

confidence: 90%

Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

Pramodkumar

Priya

Jebarani

et al. 2016

Indian J Endocr Metab

View full text Add to dashboard Cite

Aim:The aim of this study was to compare the metabolic profiles of subjects with normal glucose tolerance (NGT) with and without elevated 1-h postglucose (1HrPG) values during an oral glucose tolerance test (OGTT).Methodology:The study group comprised 996 subjects without known diabetes seen at tertiary diabetes center between 2010 and 2014. NGT was defined as fasting plasma glucose <100 mg/dl (5.5 mmol/L) and 2-h plasma glucose <140 mg/dl (7.8 mmol/L) after an 82.5 g oral glucose (equivalent to 75 g of anhydrous glucose) OGTT. Anthropometric measurements and biochemical investigations were done using standardized methods. The prevalence rate of generalized and central obesity, hypertension, dyslipidemia, and metabolic syndrome (MS) was determined among the NGT subjects stratified based on their 1HrPG values as <143 mg/dl, ≥143–<155 mg/dl, and ≥155 mg/dl, after adjusting for age, sex, body mass index (BMI), waist circumference, alcohol consumption, smoking, and family history of diabetes.Results:The mean age of the 996 NGT subjects was 48 ± 12 years and 53.5% were male. The mean glycated hemoglobin for subjects with 1HrPG <143 mg/dl was 5.5%, for those with 1HrPG ≥143–<155 mg/dl, 5.6% and for those with 1HrPG ≥155 mg/dl, 5.7%. NGT subjects with 1HrPG ≥143–<155 mg/dl and ≥155 mg/dl had significantly higher BMI, waist circumference, systolic and diastolic blood pressure, triglyceride, total cholesterol/high-density lipoprotein (HDL) ratio, triglyceride/HDL ratio, leukocyte count, and gamma glutamyl aminotransferase (P < 0.05) compared to subjects with 1HrPG <143 mg/dl. The odds ratio for MS for subjects with 1HrPG ≥143 mg/dl was 1.84 times higher compared to subjects with 1HrPG <143 mg/dl taken as the reference.Conclusion:NGT subjects with elevated 1HrPG values have a worse metabolic profile than those with normal 1HrPG during an OGTT.

show abstract

Section: Discussionsupporting

confidence: 90%

Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

Pramodkumar

Priya

Jebarani

et al. 2016

Indian J Endocr Metab

View full text Add to dashboard Cite

show abstract

“…37,38 There are few studies in Asian Indian subjects on the importance of an elevated 1HrPG value in predicting future diabetes, a condition that was termed early glucose intolerance for lack of a better name. [40][41][42] Viswanathan et al 40,41 showed that individuals with early glucose intolerance were also at risk of developing diabetes like individuals with prediabetes. Joshi and Karne 42 in an editorial emphasized the importance of doing not only the FPG and 2HrPG value during an OGTT, but also the intermediate 1-h value, as this has the potential for prevention of diabetes.…”

Section: Discussionmentioning

confidence: 99%

“…[37][38][39][40][41][42][43][44][45] Because about a third of NGT subjects have 1HrPG of ‡155 mg/dL, this opens up new possibilities for primary prevention. NGT subjects with a raised 1HrPG value could form a ''new target subgroup'' to be identified for initiating prevention measures.…”

Section: Discussionmentioning

confidence: 99%

1-Hour Venous Plasma Glucose and Incident Prediabetes and Diabetes in Asian Indians

Priya

Anjana²,

Chiwanga³

et al. 2013

Diabetes Technology & Therapeutics

View full text Add to dashboard Cite

show abstract

Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India

Kumpatla

Parveen

stanson

et al. 2019

Diabetes & Metabolic Syndrome: Clinical Research & Revi

View full text Add to dashboard Cite

Prevalence of metabolic syndrome among Asian Indian subjects with elevated intermediate glucose response during OGTT

Cited by 5 publications

References 4 publications

Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

1-Hour Venous Plasma Glucose and Incident Prediabetes and Diabetes in Asian Indians

Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India

Contact Info

Product

Resources

About

Prevalence of metabolic syndrome among Asian Indian subjects with elevated intermediate glucose response during OGTT

Cited by 5 publications

References 4 publications

Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

1-Hour Venous Plasma Glucose and Incident Prediabetes and Diabetes in Asian Indians

Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India

Contact Info

Product

Resources

About

Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India