Prevalence of metabolic syndrome in individuals undergoing comprehensive cardiac and general medical check-up at Kathmandu Medical College Teaching Hospital

Abstract

Background: Metabolic syndrome represents a constellation of metabolic derangements including insulin resistance, diabetes mellitus, obesity, dyslipidaemia and cardiovascular disease. Since it is associated with higher risk of coronary artery disease and diabetes mellitus, timely detection is important. Objectives: The main objective of the study was to find out the prevalence of metabolic syndrome in individuals undergoing comprehensive cardiac and general medical check-up at Kathmandu Medical College Teaching Hospital. The other objectives were to find the gender and ethnic prevalence of this condition. Methods: This is a hospital based cross-sectional study conducted at Kathmandu Medical College Teaching Hospital among 389 healthy participants of both gender and above 20 years of age who underwent comprehensive cardiac and general medical check-up. Metabolic Syndrome was diagnosed using US National Cholesterol Education Program Adult Treatment Panel III. Results: Out of the 389 subjects, 56 persons were found to be having metabolic syndrome (14.40%). Metabolic syndrome was more common in female and obese people and the prevalence did not differ with ethnicity. Conclusion: The prevalence of metabolic syndrome in the present study has been found to be 14.40 %. It is important to diagnose this condition in time so that subsequent complications can be prevented.Journal of Kathmandu Medical College Vol. 2, No. 3, Issue 5, Jul.-Sep., 2013 Page: 112-116DOI: http://dx.doi.org/10.3126/jkmc.v2i3.9934Uploaded date : 2/28/2014

Prevalence of metabolic syndrome in patients attending general practice outpatient department at a community hospital

“…16 Similarly, in study done by Karki et al prevalence was found to be 14.4% among individuals undergoing comprehensive cardiac and general medical checkup in Kathmandu. 19 The prevalence was found to be quite high comprising 20 Prevalence of MS was found to be slightly higher among male in this study with male:female = 1.09:1; however it was found to more prevalent among female in studies done by Timalsina et al, Karki et al, and Srinivasan et al comprising 62.5%, 75.7%, and 65.2% respectively. [18][19][20] Metabolic syndrome is most commonly associated with advancing age and obesity.…”

“…19 The prevalence was found to be quite high comprising 20 Prevalence of MS was found to be slightly higher among male in this study with male:female = 1.09:1; however it was found to more prevalent among female in studies done by Timalsina et al, Karki et al, and Srinivasan et al comprising 62.5%, 75.7%, and 65.2% respectively. [18][19][20] Metabolic syndrome is most commonly associated with advancing age and obesity. The findings of this study are in concordance with the finding of other studies.…”

“…However, in a study done among type II diabetic patients, increased fasting sugar was found to be the most predominant component, 17,18 whereas high triglyceride was the most predominant component followed by low HDL cholesterol in a study done by Karki et al 19 The high prevalence MS among patients with diabetes and hypertension could be due to lack of awareness and unhealthy lifestyle. 22 A comprehensive management plan could be assembled through an "ABCDE" approach: "A" for assessment of cardiovascular risk and aspirin therapy, "B" for blood pressure control, "C" for cholesterol management, "D" for diabetes prevention and diet therapy, and "E" for exercise therapy.…”