Prevalence of metabolic syndrome is comparable between inflammatory bowel disease patients and the general population

Nagahori, Masakazu; Hyun, Sea Bong; Totsuka, Teruji; Okamoto, Ryuichi; Kuwahara, Erika; Takebayashi, Toru; Naganuma, Makoto; Watanabe, Mamoru

doi:10.1007/s00535-010-0247-z

Cited by 29 publications

(28 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…21,22 Overnutrition (and as a consequence obesity) is now encountered in an increasing proportion of patients with IBD, as it is in the general community. 23 The interest in obesity has been amplified by the concept that mesenteric fat might drive intestinal inflammation in patients with Crohn's disease. 24 Whether obesity is indeed associated with an adverse natural history is currently unclear from the literature, although obesity is likely to affect surgical complexity and morbidity.…”

Section: Protein and Energy Statusmentioning

confidence: 99%

Dietary management of IBD—insights and advice

Halmos

Gibson

2015

Nat Rev Gastroenterol Hepatol

View full text Add to dashboard Cite

The current general interest in the use of food choice or diet in maintaining good health and in preventing and treating disease also applies to patients with IBD, who often follow poor or nutritionally challenging dietary plans. Unfortunately, dietary advice plays only a minor part in published guidelines for management of IBD, which sends a message that diet is not of great importance. However, a considerable evidence base supports a focused and serious attention to nutrition and diet in patients with IBD. In this Review, a step-wise approach in the evaluation and management of these patients is proposed. First, dietary intake and eating habits as well as current nutritional state should be documented, and corrective measures instituted. Secondly, dietary strategies as primary or adjunctive therapy for the reduction of inflammation and/or prevention of relapse of IBD should be seriously contemplated. Thirdly, use of diet to improve symptoms or lessen the effects of complications should be considered. Finally, dietary advice regarding disease prevention should be discussed when relevant. An increasing need exists for applying improved methodologies into establishing the value of current and new ways of using food choice as a therapeutic and preventive tool in IBD.

show abstract

Section: Protein and Energy Statusmentioning

confidence: 99%

Dietary management of IBD—insights and advice

Halmos

Gibson

2015

Nat Rev Gastroenterol Hepatol

View full text Add to dashboard Cite

show abstract

“…An interesting example of intra-abdominal fat accumulation in subjects free of metabolic disease7 and who are frequently underweight is Crohn's disease (CD), a chronic relapsing inflammatory process that can affect any part of the gastrointestinal tract 8. In the first description of this disease, Crohn et al reported the peculiar presence of an enlarged mesenteric adipose tissue that envelops more than half of the intestinal circumference in corresponding inflammatory lesions 8 9.…”

Section: Introductionmentioning

confidence: 99%

Visceral adipocytes: old actors in obesity and new protagonists in Crohn's disease?

Zulian

Cancello

Micheletto

et al. 2011

Gut

View full text Add to dashboard Cite

show abstract

“…The most current investigations have been directed toward the identification of metabolic syndrome among individuals with IBD, with prevalence rates ranging from 7.1 to 17.7% among patients with CD and 16.0 to 29.5% among those with UC (25,34,47) . However, the prevalence of metabolic syndrome varies widely depending on the criteria employed and the WC is one of the variables used to define this condition.…”

Section: Discussionmentioning

confidence: 99%

Excessive Weight – Muscle Depletion Paradox and Cardiovascular Risk Factors in Outpatients With Inflammatory Bowel Disease

Andrade

Maio

Dourado

et al. 2015

Arq. Gastroenterol.

View full text Add to dashboard Cite

-Background -Evidence suggests a nutritional transition process in patients with inflammatory bowel disease. Obesity, which was once an uncommon occurrence in such patients, has grown in this population at the same prevalence rate as that found in the general population, bringing with it an increased risk of cardiovascular disease. Objective -The aim of the present study was to determine the nutritional status and occurrence of cardiovascular risk factors in patients with inflammatory bowel disease. Methods -A case-series cross-sectional study was conducted involving male and female adult outpatients with inflammatory bowel disease. Data were collected on demographic, socioeconomic, clinical and anthropometric variables as well as the following cardiovascular risk factors: sedentary lifestyle, excess weight, abdominal obesity, medications in use, comorbidities, alcohol intake and smoking habits. The significance level for all statistical tests was set to 5% (P < 0.05). Results -The sample comprised 80 patients with inflammatory bowel disease, 56 of whom (70.0%) had ulcerative colitis and 24 of whom (30.0%) had Crohn's disease. Mean age was 40.3±11 years and the female genre accounted for 66.2% of the sample. High frequencies of excess weight (48.8%) and abdominal obesity (52.5%) were identified based on the body mass index and waist circumference, respectively, in both groups, especially among those with ulcerative colitis. Muscle depletion was found in 52.5% of the sample based on arm muscle circumference, with greater depletion among patients with Crohn's disease (P=0.008). The most frequent risk factors for cardiovascular disease were a sedentary lifestyle (83.8%), abdominal obesity (52.5%) and excess weight (48.8%). Conclusion -The results of the complete anthropometric evaluation draw one's attention to a nutritional paradox, with high frequencies of both -muscle depletion, as well as excess weight and abdominal obesity. HEADINGS -Inflammatory bowel disease. Overweight. Malnutrition. Risk factors. Cardiovascular disease.

show abstract

Prevalence of metabolic syndrome is comparable between inflammatory bowel disease patients and the general population

Abstract: Prevalence of metabolic syndrome in our IBD patients was comparable to that of the general population. Because age was the independent risk factor for developing MS, evaluation for MS is needed for elderly IBD patients.

Cited by 29 publications

References 32 publications

Dietary management of IBD—insights and advice

Dietary management of IBD—insights and advice

Visceral adipocytes: old actors in obesity and new protagonists in Crohn's disease?

Excessive Weight – Muscle Depletion Paradox and Cardiovascular Risk Factors in Outpatients With Inflammatory Bowel Disease

Contact Info

Product

Resources

About