Prevalence of microalbuminuria among sudanese type 2 diabetic patients at elmusbah center at ombadda - omdurman

Rahamtalla, Fayza A.

doi:10.9790/3013-25205155

Cited by 7 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The rise in the prevalence of diabetic nephropathy in our study might be a result of apparent deficiency in the primary health care during the last five years in Yemen because of the war and political conflicts. Although the prevalence of microalbuminuria was unexpectedly high, this is consistent with studies in Saudi Arabia (45.6%) [28], in Sudan 44% [29] and in Kuwait 58.2% [30].…”

Section: Discussionsupporting

confidence: 89%

Prevalence of Proteinuria among Type 2 Diabetic Patients in Dhamar Governorate, Yemen

Ali¹,

Daiffallah²,

Al³

2019

Int J Diabetes Clin Res

View full text Add to dashboard Cite

Background: Diabetic nephropathy remains the most common cause of end-stage renal disease (ESRD) worldwide. Microalbuminuria is the first clinical sign of renal dysfunction in patients with diabetes mellitus. A urine total protein: creatinine ratio (TPCR) is a convenient and inexpensive measure of proteinuria and could be used to predict the presence of microalbuminuria in diabetic patients. Objective:The aim of this study was to assess the prevalence and associated risk factors of proteinuria among type-2 diabetic patients in Dhamar governorate, Yemen.Method: This was a cross sectional study, spot urine TPCR was performed on 200 diabetic patients who attended the diabetic clinic at Dhamar General Hospital and Al-Wahda Teaching Hospital from March 2016 to June 2016.Results: This study indicated higher prevalence of pathological proteinuria (TPCR ≥ 150 mg/g of creatinine) 64% of the study population. Estimated urine albumin-to-creatinine ratio (ACR) revealed that 49% of the diabetic patients had microalbuminuria (ACR 30-300 mg/g) and 25.5% was estimated as macroalbuminuria (ACR > 300 mg/g). Multivariate analysis revealed that the Hypertension (

show abstract

Section: Discussionsupporting

confidence: 89%

Prevalence of Proteinuria among Type 2 Diabetic Patients in Dhamar Governorate, Yemen

Ali¹,

Daiffallah²,

Al³

2019

Int J Diabetes Clin Res

View full text Add to dashboard Cite

show abstract

“…Our diabetic population was characterized by a female majority, as described in the literature [ 18 , 19 ]. Different distributions were found though [ 20 , 21 ]. The mean age (61.4 years) and the mean duration of diabetes (8.1 years (SD: 6.4)) were similar to those reported by other authors [ 13 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Screening for Nephropathy in Diabetes Mellitus: Is Micral-Test Valid among All Diabetics?

Afifa

Asma

Nabil

et al. 2016

International Journal of Chronic Diseases

View full text Add to dashboard Cite

Background. Using Micral-test (MT) for screening microalbuminuria (MA) among type 2 diabetics (T2D) is helpful. We aimed at determining prevalence of MA and at describing the MT validity. Methods. We studied 182 T2D followed up in family medicine. Two 24-hour urinary quantitative assays of MA had been used as a gold standard. Results. Prevalence of MA was 23%, CI 95%: 16.9–29.1. MT validity was 77% for sensitivity, 88% for negative predictive value, and 0.2 for Kappa coefficient (p = 0.001). Among subjects having a blood pressure ≥130/80 mmHg, having a CHT/HDL ratio ≥ 3, being a T2D for more than 5 years, and being women, negative predictive values were, respectively, 91%, 89%, 95%, and 91%. The area under the ROC curve was 0.81 in men (p = 0.008) and 0.80 when diabetes duration exceeds 5 years (p = 0.001). The MA value at 100% Sp for MT was 35 mg/L. Conclusion. The use of MT in primary healthcare for yearly screening for MA in T2D must be accentuated especially when diabetes duration exceeds 5 years or when associated with other cardiovascular risks.

show abstract

“…Using Bland-Altman method of comparative analysis which 3). diabetes subjects [29]. Abundant research has shown that diabetes and its complications play a significant role in the dysfunction of the glomerular basement membrane (GBM) filtration barrier; thus, albumin can be secreted into urine [30][31][32].…”

Section: Data Are Presented As Absolute Values: Cg -Cockcroft-gault 4...mentioning

confidence: 99%

Evaluation of the Three Main Estimated Glomerular Filtration Rate (eGFR) Equations in a Black African Population: A Cross-Sectional Study among Type 2 Diabetes Patients in Ghana

Togbe¹,

Annani-Akollor²,

Donkor³

et al. 2023

MJNH

View full text Add to dashboard Cite

Background: Almost all Glomerular filtration rate (GFR) equations were derived from populations primarily consisting of whites (Caucasians) with chronic kidney disease (CKD). Although the race correction factor for African Americans has been extrapolated to Black Africans, studies in some parts of Africa suggest that the use of the race factor for Black Africans may be inappropriate. Thus, this study sought to assess how well the Cockcroft-Gault (CG), 4-variable Modification of Diet and Renal Disease (4v-MDRD) and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations work in a Ghanaian population at risk of CKD. Methods: The study involved 81 diabetic males and 324 diabetic females attending the Komfo Anokye Teaching Hospital (KATH) in Ghana. Blood and urine samples were collected, and serum creatinine measured in blood was used in GFR estimation using the CG, 4v-MDRD, and CKD-EPI equations. Data was analyzed using GraphPad Prism version 5.00 and SPSS version 20, both of which are known for their accuracy, precision, practicality and consistency. Results were expressed as mean ± SD. Unpaired t-test and one-way analysis of variance (ANOVA) was used to compare mean values of continuous variables, and Pearson's correlation and linear regression were used to test for associations. Chisquare test was also used to test for associations between categorized variables. Agreement between the three CKD equations was assessed by the Bland-Altman statistic. Statistical significance was defined as p-value <0.05. The study was approved by the Committees on Human Research Publications and Ethics (CHRPE), and the Research and Development Unit of KATH. The study was conducted in accordance with the Helsinki Declaration and its later amendments or comparable ethical standards.Written consent was obtained from all participants. Results: Estimated

show abstract

Prevalence of microalbuminuria among sudanese type 2 diabetic patients at elmusbah center at ombadda - omdurman

Cited by 7 publications

References 17 publications

Prevalence of Proteinuria among Type 2 Diabetic Patients in Dhamar Governorate, Yemen

Prevalence of Proteinuria among Type 2 Diabetic Patients in Dhamar Governorate, Yemen

Screening for Nephropathy in Diabetes Mellitus: Is Micral-Test Valid among All Diabetics?

Evaluation of the Three Main Estimated Glomerular Filtration Rate (eGFR) Equations in a Black African Population: A Cross-Sectional Study among Type 2 Diabetes Patients in Ghana

Contact Info

Product

Resources

About