Prevalence of Mild Cognitive Impairment and Its Subtypes in the Mexican Population

Juárez‐Cedillo, Teresa; Sánchez-Arenas, Rosalinda; Sánchez-Garcí­a, Sergio; García-Peña, Carmen; Hsiung, Ging-Yuek Robin; Sepehry, Amir Ali; Beattie, B. Lynn; Jacova, Claudia

doi:10.1159/000345251

Cited by 56 publications

(59 citation statements)

References 40 publications

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“…The results of this study showed that those individuals with a high risk for CVD and depression were more likely to have a diagnosis of MCI. Our findings are also consistent with results from the Study on Aging and Dementia in Mexico, which found that heart disease, stroke, and depression were associated with an increased risk of MCI [61]. …”

Section: Discussion/conclusionsupporting

confidence: 91%

Vascular Depression and Cognition in Mexican Americans

Johnson¹,

Large

Munoz

et al. 2019

Dement Geriatr Cogn Disord

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Background: Mexican Americans are at increased risk of developing mild cognitive impairment (MCI) and Alzheimer’s disease compared to non-Hispanic whites. This study sought to examine the relationship between vascular risk, depression, and cognition in Mexican American elders. Methods: Data from 470 (390 normal controls, 80 MCI patients) Mexican Americans enrolled in the Health and Aging Brain among Latino Elders (HABLE) study were used. The cardiovascular risk was assessed by the Framingham Risk Score. Cognition was assessed with a neuropsychological battery, and depression was assessed based on scores from the Geriatric Depression Scale (GDS). ANOVAs were utilized to determine the differences in neuropsychological scores of normal controls with and without depression and CVD risk (low vs. high). Follow-up logistic regression was conducted to determine MCI risk. Results: The results of this study indicated that comorbid depression and a high CVD risk were associated with poorer cognitive performance in Mexican Americans. Depressed women with high CVD risk were more likely to have executive dysfunction, language deficits, and poorer global cognition than nondepressed women with a high CVD risk. In Mexican American men, those with a high vascular risk and depression were more likely to have executive dysfunction and poorer immediate memory than the nondepressed high-risk group. Higher GDS scores (OR = 1.10; 95% CI 1.02–1.10, p = 0.001) and higher vascular risk scores (OR = 1.05; 95% CI 1.02–1.10, p = 0.001) significantly predicted MCI status in Mexican Americans. Conclusion: The results of this study indicated that comorbid depression and a high CVD risk were associated with poorer cognitive performance and increased risk of MCI in Mexican Americans.

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Section: Discussion/conclusionsupporting

confidence: 91%

Vascular Depression and Cognition in Mexican Americans

Johnson¹,

Large

Munoz

et al. 2019

Dement Geriatr Cogn Disord

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“…Frailty affects 20% of the population aged 75 years and older, and its consequences range from loss of mobility to dependence, institutionalization, hospitalization and death [3,4]. Additionally, mild cognitive impairment (MCI) is considered to be a transitional state between the natural evolution of cognitive ability with age and premature dementia [5,6]. Cognitive impairment has been shown to be associated with adverse health outcomes related to frailty and has even been considered as a component of frailty [7].…”

Section: Introductionmentioning

confidence: 99%

Dual Task Gait Performance in Frail Individuals with and without Mild Cognitive Impairment

Martínez-Ramírez¹,

Martinikorena²,

Lecumberri³

et al. 2016

Dement Geriatr Cogn Disord

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Background: Several studies have stated that frailty is associated with cognitive impairment. Based on various studies, cognition impairment has been considered as a component of frailty. Other authors have shown that physical frailty is associated with low cognitive performance. Dual task gait tests are used as a strong predictor of falls in either dementia or frailty. Consequently, it is important to investigate dual task walking tests in elderly populations including control robust oldest old, frail oldest old with mild cognitive impairment (MCI) and frail oldest old without MCI. Methods: Dual task walking tests were carried out to examine the association between frailty and cognitive impairment in a population with advanced age. Forty-one elderly men and women participated in this study. The subjects from control, frail with MCI and frail without MCI groups, completed the 5-meter walk test at their own gait velocity. Arithmetic and verbal dual task walking performance was also assessed. Kinematic data were acquired from a unique tri-axial inertial sensor. Results: The spatiotemporal and frequency parameters related to gait disorders did not show any significant differences between frail with and without MCI groups. Conclusions: The evaluation of these parameters extracted from the acceleration signals led us to conclude that these results expand the knowledge regarding the common conditions in frailty and MCI and may highlight the idea that the impairment in walking performance does not depend of frailty and cognitive status.

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“…Criteria for determining presence of cognitive impairment and dementia have been described previously (Juarez-Cedillo et al, 2012). Criteria for determining presence of cognitive impairment and dementia have been described previously (Juarez-Cedillo et al, 2012).…”

Section: Methodsmentioning

confidence: 99%