Prevalence of Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus in Northeastern Saudi Hospitals

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for serious threats to human health, causing various syndromes worldwide. Here, our purpose was to estimate the prevalence of nosocomial MRSA among isolates from King Khalid Hospital (KKH) and Maternity and Children Hospital (MCH) at Hafar Al-Batin Governorate, Saudi Arabia, and to determine the resistance of these isolates to common antibiotics used for treatment. One-hundred clinical specimens were collected from admitted patients during a six month period, and subjected to MRSA screening using traditional microbiological techniques. Antimicrobial susceptibility testing (AST) was also performed and confirmed by the VITEK2 automated system. Among the 37 S. aureus strains isolated from KKH, 23 (62.16%) were identified as MRSA. In MCH, 38 (60.31%) out 63 isolated strains were identified as MRSA. According to AST, few MRSA strains were resistant to teicoplanin, fosfomycin, linezolid, and mupirocin in both hospitals. Vancomycin resistance was not detected in any of the MRSA strains. Twelve MRSA strains from KKH and 17 strains from MCH were considered multidrug resistant (MDR). In conclusion, prevention is critical to reduce the high prevalence of MRSA.

Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) at a maternity and children hospital in Saudi Arabia: A cross-sectional study

“…Locally, Alaklobi and colleagues found that the prevalence of MRSA was 23.3 % among outpatient children in Riyadh Saudi Arabia ( Alaklobi et al, 2015 ). While MRSA prevalence was 60 % in a maternity hospital in Hafar Al-Batin in eastern region in Saudi Arabia ( Aljeldah et al, 2022 ). Globally, the range of MRSA prevalence in maternal patients ranges from 2.1 % to 41 % ( Chen et al, 2006 , Reusch et al, 2008 , Nourollahpour Shiadeh et al, 2022 ).…”

Synthesis of Green Copper Nanoparticles Using Medicinal Plant Krameria sp. Root Extract and Its Applications

“…Then, tissue was dried at room temperature under shade, ground with the help of an electric grinder, and stored. Escherichia coli , Staphylococcus aureus , Alternaria alternata , and Fusarium oxyporium were brought from previous work at the University of Hafr Al Batin [ 30 ]. All the required chemicals, i.e., copper salt (CuSO 4 ·5H 2 O) was bought from Sigma–Aldrich through Science Traders.…”

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“…Planning an updated treatment regimen requires frequent knowledge of the local antimicrobial sensitivity pattern [12]. The prevalence of UTIs is high, and bacterial resistance to antibiotics is spreading globally, especially in Saudi Arabia [13].…”