Prevalence of myocardial ischemia during mechanical ventilation and weaning and its effects on weaning success

Frazier, Susan K.; Brom, Heather; Widener, Jeanne; Pender, Lauren; Stone, Kathleen S.; Moser, Debra K.

doi:10.1016/j.hrtlng.2005.12.006

Cited by 39 publications

(42 citation statements)

References 28 publications

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“…[5][6][7] Thus, establishing a simple and noninvasive method to detect cardiac dysfunction in patients who are difficult to wean from mechanical ventilation is important.…”

Section: Introductionmentioning

confidence: 99%

N-terminal prohormone B-type natriuretic peptide and weaning outcome in postoperative patients with pulmonary complications

Liao

Qiu

et al. 2013

J Int Med Res

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Objective: To evaluate the relationship between plasma N-terminal prohormone B-type natriuretic peptide (NT-proBNP) and weaning outcomes, and the ability of NT-proBNP level to predict weaning success, in cancer patients with pulmonary complications undergoing noncardiac major surgeries. Methods: Patients who were mechanically ventilated following postoperative respiratory failure were enrolled. NT-proBNP levels at the end of a 2-h spontaneous breathing trial were measured. Weaning was considered a success in patients who completed the trial and maintained spontaneous breathing following extubation for >48 h. Results: Out of 29 patients, 22 patients weaned successfully but weaning failed in 7 patients. Plasma NT-proBNP was significantly higher in the weaning failure group than in the weaning success group. For predicting weaning success, the optimal NT-proBNP threshold value at the end of the spontaneous breathing trial was <448 ng/l (receiver operating characteristic analysis; sensitivity 68.18%, specificity 85.71%, positive predictive value 93.7% and negative predictive value 46.2%). Conclusion: Measuring NT-proBNP at the end of a spontaneous breathing trial may assist in predicting weaning success, as a noninvasive, quantitative and repeatable indicator of cardiac stress in patients with postsurgical respiratory failure.

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“…[5][6][7] Thus, establishing a simple and noninvasive method to detect cardiac dysfunction in patients who are difficult to wean from mechanical ventilation is important.…”

Section: Introductionmentioning

confidence: 99%

N-terminal prohormone B-type natriuretic peptide and weaning outcome in postoperative patients with pulmonary complications

Liao

Qiu

et al. 2013

J Int Med Res

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“…Frazier et al 15 found a higher prevalence of myocardial ischemia, but no significant difference in the weaning success between patients with ischemia and patients without ischemia. The study by Frazier et al did not add any valuable findings to build the case for lead placement, but results of that study do show that myocardial ischemia is more prevalent than Chatila et al 17 reported in 1996.…”

Section: Mechanical Ventilator Research and Findingsmentioning

confidence: 95%

“…The articles were examined for original research related to our target population: noncardiac ICU patients. Nine research studies, 9,14,15,17,[20][21][22][23][24] Suggest more research to determine whether incidence is greater in different groups…”

Section: Search Strategiesmentioning

confidence: 99%

“…"At risk" groups for SMI include postoperative surgical patients 14 ; patients with sepsis, inflammation, or electrolyte imbalances; and patients undergoing intermittent hypoxemia due to endotracheal tube suctioning. 15,16 The frequency of silent ischemia during weaning from mechanical ventilators suggests that the risk for weaning failure is increased when SMI has occurred. 17 The consequences of undetected SMI can be severe.…”

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confidence: 99%

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Continuous ST-Segment Monitoring in the Intensive Care Unit

Fox

Kirkendall

Craney

2010

Critical Care Nurse

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“…However, in the present patient, the improvement in coronary perfusion following angioplasty contributed significantly to the success of weaning and extubation. Despite the known pathophysiological relationships between myocardial hypoperfusion and weaning failure [3], and the high frequency of weaning-induced myocardial ischaemia [4], this strategy is not proposed in currently available guidelines [5]. Surprisingly, it is only the second report of such a case [6].…”

mentioning

confidence: 99%

Myocardial ischaemia and weaning failure: is angioplasty the heart of the problem?

et al. 2011

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Prevalence of myocardial ischemia during mechanical ventilation and weaning and its effects on weaning success

Cited by 39 publications

References 28 publications

N-terminal prohormone B-type natriuretic peptide and weaning outcome in postoperative patients with pulmonary complications

N-terminal prohormone B-type natriuretic peptide and weaning outcome in postoperative patients with pulmonary complications

Continuous ST-Segment Monitoring in the Intensive Care Unit

Myocardial ischaemia and weaning failure: is angioplasty the heart of the problem?

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