Prevalence of Neisseria meningitidis carriers in children under five years of age and teenagers in certain populations of Mexico City

Monteros, Luz Elena Espinosa de los; Aguilar-Ituarte, Felipe; Jiménez-Rojas, Leticia Verónica; Kuri, Pablo; Rodríguez-Suárez, Romeo S; Gómez-Barreto, Demóstenes

doi:10.1590/s0036-36342009000200006

Cited by 18 publications

(21 citation statements)

References 22 publications

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“…We estimated the nasopharyngeal N. meningitidis carriage to be 2.7%, which appear lower than the generally quoted overall rate of 10% [70], and the average 3.5–35% reported in studies conducted in Africa [71], but at least consistent with that reported in Mexico (1.6%) [72]. The low carriage rates found in our study and those reported in Mexico are consistent with the low disease incidence rate reported in these two countries.…”

Section: Resultssupporting

confidence: 51%

Burden of Neisseria meningitidis infections in China: a systematic review and meta–analysis

Zhang

Dong

Guo

et al. 2016

Journal of Global Health

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BackgroundNeisseria meningitidis is a leading cause of bacterial meningitis and septicemia in children and young adults worldwide. The disease burden associated with N. meningitidis infections has not been systematically assessed in China. Therefore, we undertook this study to determine the burden of meningococcal disease in China.MethodWe performed a systematic review and meta–analysis of articles on N. meningitidis incidence, carriage, seroprevalence and mortality rates in China by searching the Chinese BioMedical Database (CBM), China National Knowledge Infrastructure (CNKI), Wanfang database and PubMed for publications from January 2005 to Aug 2015.ResultsIn total, 50 articles were included in our analysis. The overall incidence of meningococcal disease and associated mortality were estimated to be 1.84 (95% confidence interval (CI) 0.91–3.37) per 100 000 persons per year and 0.33 (95% CI 0.12–0.86) per 100 000 persons per year, respectively. N. meningitidis carriage rate among the healthy population was estimated to be 2.7% (95% CI 2.0–3.5%). Prevalence of antibodies against N. meningitidis serogroup A and C were estimated to be 77.3% (95% CI 72.4%–81.6%) and 33.5% (95% CI 27.0%–40.8%), respectively. No studies were found for serogroup specific disease burden.ConclusionsThe overall incidence of meningococcal disease in China is low. The lower seroprevalence of serogroup C within the population suggests that it may pose a greater risk for meningococcal disease outbreak than serogroup A. The lack of data on serogroup disease burden by age groups suggests the implementation of laboratory based meningococcal surveillance systems are urgently needed in China.

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Section: Resultssupporting

confidence: 51%

Burden of Neisseria meningitidis infections in China: a systematic review and meta–analysis

Zhang

Dong

Guo

et al. 2016

Journal of Global Health

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“…1). Of these, 14 met the inclusion criteria and were included in the review, including seven studies from Brazil [33][34][35][36][37][38][39], three from Chile [40][41][42], and one each from Colombia [43], Cuba [32], Mexico [44], and Paraguay [45] (Fig. 2; Table 2).…”

Section: Literature Search Findings On Carriage In the Americasmentioning

confidence: 99%

“…One publication assessed carriage in Mexico. Espinosa de los Monteros and colleagues reported the epidemiology of N. meningitidis carriage isolates in children younger than 5 years and adolescents in Mexico City from September 2004 to April 2005 [44]. Using a nonprobabilistic group sampling method from the healthy population, investigators studied children attending daycare centers (n = 736) and adolescents in social rehabilitation centers (n = 774) or attending universities (n = 800); 2310 nasopharynx swabs were obtained from these individuals.…”

Section: Mexicomentioning

confidence: 99%

Carriage of Neisseria Meningitidis in Low and Middle Income Countries of the Americas and Asia: A Review of the Literature

2020

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Introduction: Meningococcal colonization, or carriage, can progress to invasive meningococcal disease, a serious public health concern, with rapid progression of disease and severe consequences if left untreated. Information on meningococcal carriage and epidemiology in low/middle income American and Asian countries remains sparse. These data are crucial to ensure that appropriate preventive strategies such as vaccination can be implemented in these regions. The goal of this study was to summarize the Neisseria meningitidis carriage literature in low and middle income countries of the Americas and Asia. Methods: Target countries were categorized as low and middle income according to the International Monetary Fund classification of low income/developing economies and middle income/emerging market economies, respectively. A PubMed search identified Englishlanguage publications that examined carriage in these countries. Studies reporting the epidemiology of N. meningitidis carriage or assessing risk factors for carriage were included. Results: Fourteen studies from the Americas [Brazil (n = 7), Chile (n = 3), and Colombia, Cuba, Mexico, and Paraguay (n = 1 each)] and nine from Asia [China (n = 2), India (n = 3), and Malaysia, Nepal, Philippines, and Thailand (n = 1 each)] were identified; an additional Cuban study from the authors' files was also included. Studies were not identified in many target countries, and substantial diversity was observed among study methodologies, populations, and time periods, thereby limiting comparison between studies. The carriage rate in the Americas ranged from 1.6% to 9.9% and from 1.4% to 14.2% in Asia. Consistent risk factors for carriage were not identified. Conclusions: There is a lack of comprehensive and contemporary information on meningococcal carriage in low and medium income countries of the Americas and Asia. Future Digital Features To view digital features for this article go to https://doi.org/10.6084/m9.figshare. 11962566.

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“…Of the published data identified, information relating to carriage is limited to children and adolescents from small populations residing within limited geographical areas [63, 64]. A carriage prevalence of 1·9% in children and 2·9% in adolescents was reported in Mexico [64], with Nm serogroups C and Y being the most frequently detected. Similarly, carriage of Nm was found to be 1·5% in a sample of schoolchildren in Venezuela [63].…”

Section: Introductionmentioning

confidence: 99%

The epidemiology of meningococcal disease in Latin America 1945–2010: an unpredictable and changing landscape

Sáfadi

Gonzalez-Ayala

Jäkel³

et al. 2012

Epidemiol. Infect.

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SUMMARYMeningococcal disease is mostly endemic in Latin America, with periodic occurrences of outbreaks and epidemics over the last few decades. This literature review summarizes the available epidemiological data for this region between 1945 and 2010. Incidence rates and serogroup distribution differ from country to country and over time. Serogroups A, B, and C have all been major causes of meningococcal disease since the 1970s. In the last decade serogroups W135 and Y may now be emerging in certain countries, with serogroup A virtually disappearing. Although progress has been made in improving and coordinating the surveillance of invasive disease, the uniformity and quality of reported data reflect the fact that the current surveillance systems focus on passive rather than active reporting, hence the reliability of data may vary between countries. Consideration of vaccination policies to control meningococcal disease can only be made with a sufficient understanding of the changing epidemiology in the region.

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Prevalence of Neisseria meningitidis carriers in children under five years of age and teenagers in certain populations of Mexico City

Abstract: Prevalence of Neisseria meningitidis carriers in children under five years of age and teenagers in certain populations of Mexico City.

Cited by 18 publications

References 22 publications

Burden of Neisseria meningitidis infections in China: a systematic review and meta–analysis

Burden of Neisseria meningitidis infections in China: a systematic review and meta–analysis

Carriage of Neisseria Meningitidis in Low and Middle Income Countries of the Americas and Asia: A Review of the Literature

The epidemiology of meningococcal disease in Latin America 1945–2010: an unpredictable and changing landscape

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