Prevalence of nickel and cobalt allergy among female patients with dermatitis before and after Danish government regulation: A 23-year retrospective study

Thyssen, Jacob P.; Johansen, Jeanne Duus; Carlsen, Berit Christina; Menné, Torkil

doi:10.1016/j.jaad.2009.03.030

Cited by 82 publications

(91 citation statements)

References 39 publications

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“…For example, young Danish women (18-35 years) who had ear piercing before 1990 experienced a significantly higher prevalence of allergy to nickel than women who had piercings after 1990 (ref. 11,12 ). When analysing the results of PT from 82 991 patients during the years 1992 to 2001 in Germany, sensitisation decreased among women younger than 30 years from 36.7% to 25.8% (ref.…”

Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Tichý¹,

Karlová²

2015

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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and evaluate their dynamics in comparison with similar studies in the Czech Republic and internationally carried out in previous years. Methods. A total of 1941 patients with suspected ACD were examined using the patch tests from the European Standard Series. The data obtained were subjected to statistical analysis. Results. The most common contact allergy was to nickel (15.4%), the second most frequent allergen was Balsam of Peru (11.6%). The top five allergens in the whole sample also included, in descending order, fragrance-mix I (7.1%), cobalt chloride (6.4%), and Kathon CG (4.0%). While the order of contact allergens causing sensitisation in women is consistent with the results of the whole sample, in men instead of cobalt and Kathon CG, epoxy resin and chromium appeared among the five most common allergens. Conclusions. In the Czech Republic, despite existing EU legislation, action to reduce the frequency of sensitization to nickel failed in contrast to other EU countries. In addition to nickel, consistent preventive measures should be focused mainly on sensitization to Balsam of Peru, cobalt, epoxy resins, chromium and aromatic substances and preservatives used in the cosmetic industry.

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Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Tichý¹,

Karlová²

2015

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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“…na bijuteria poderá ser responsável por esta tendência, embora a libertação de Co testada nestes produtos tenha sido mínima. 26,27 Nos últimos 20 anos, o número de casos de DCA ocupacional relacionada com os metais, na nossa população, tem vindo a diminuir de forma estatisticamente significativa. Isto poderá ser explicado, em parte, pela melhoria das condições de higiene-segurança no trabalho (em fábricas, indústria, construção civil, salões de cabeleireiro), com menor exposição aos alérgenos, mas também pela Directiva comunitária relacionada com o cimento.…”

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Alergia de Contacto a Metais num Período de 20 Anos no Centro de Portugal: Implicações das Directivas Europeias

2014

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[Cr]) along the last 20 years, particularly considering age, sex and its relation with occupational activity. Results: Out of 5 250 consecutively patch-tested patients, 1 626 (31%) were reactive to at least one metal (26.5% to Ni; 10.0% to Co and 7.9% to Cr). Women had a higher prevalence of sensitization to Ni (34.4% vs 8.9%) whereas men were more reactive to Cr (11.5% vs 5.0%). Nickel sensitization did not decrease significantly over the years, although in recent years among women sensitized to nickel the percentage of younger patients (16-30 years-old) is significantly lower (p < 0.001). Chromium sensitization significantly decreased, particularly in men (r = -0.535), and mainly in the construction workers (r = -0.639). Chromium reactivity associated with the shoe dermatitis has remained stable. Discussion: We emphasize the higher and stable percentage of nickel sensitized individuals suggesting, so far, a low impact from the EU Ni directive, although a decreasing percentage in the the younger group among Ni sensitized women may suggest a beneficial effect is becoming evident is this age group. On the contrary, the impact of the directive regarding the modification of Cr in cement seems to be effective. There is now a need to regulate chromium content in leather products, namely in shoes. Conclusions:The regulation of interventional measures related either to the manufacture and trade of adornments or professional use will better protect the population of allergy to metals.

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“…Certain governments (e.g., in Denmark) accepted this limitation 10 years before the EU directive, and the effect of this regulation is already observable. A decrease in nickel allergy prevalence has been witnessed among young Danish females in the general population 15 as well as among dermatitis patients visiting private practices 16 and university clinics 17 . This trend was also noted in other EU countries, namely Sweden and Germany.…”

Section: Epidemiologymentioning

confidence: 87%

The many faces of nickel allergy

Darlenski

Kazandjieva²,

Pramatarov

2012

Int J Dermatology

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Hypersensitivity reactions to nickel are one of the most common in the modern world. Nickel allergy prevalence is constantly growing in many countries and represents a major health and socioeconomic issue. Herein the current understanding on nickel allergy is summarized with a practical approach to the dermatologist, allergist, and general practitioner. The personal experience with some practical clinical cases of nickel dermatitis is shared. A special emphasis is put on the possible strategies for treatment and prevention of the disease.

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Prevalence of nickel and cobalt allergy among female patients with dermatitis before and after Danish government regulation: A 23-year retrospective study

Cited by 82 publications

References 39 publications

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Alergia de Contacto a Metais num Período de 20 Anos no Centro de Portugal: Implicações das Directivas Europeias

The many faces of nickel allergy

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