Prevalence of oral lichen planus among a sample of the Egyptian population

Abstract

Objectives: To report on the prevalence of oral lichen planus among a sample of the Egyptian population. Study Design: 4470 Egyptian patients, aged 15-75 years, were seen at the outpatient clinic at the Faculty of Oral and Dental Medicine, Cairo University, Egypt. 31.25 % of these patients were males and 68.75% were females. Oral mucosal lesions consistent with oral lichen planus (OLP) were identified both clinically and confirmed histologically (in atypical cases) so that the prevalence of oral lichen planus in this study is 1.43%. Results: 64 patients were diagnosed with OLP (20 males and 44 females). The average age of the affected group was 48.07 years. Associated skin lesions were detected in 15/64 patients (23.44%) and tobacco habits was observed in 20/64 patients (31.25%). The average period of follow-up of the affected cases was 1-2 years, during which two cases developed squamous cell carcinoma of the oral lesion. Conclusions: Within the limitations of this study it revealed the prevalence of OLP among middle-aged women. Atrophic lesions were most frequent, followed by the erosive forms. Anti-HCV circulating antibodies were more common in patients with OLP and, notably, OLP was associated with Diabetes mellitus in 15.63% of patients. Key words:Prevalence, oral lichen planus, Egypt.

Psychological disorders and quality of life in oral lichen planus patients and a control group

“…As other authors had prior (Ingafou, Leao, Porter, & Scully, ; Lauritano et al, ; Mostafa & Ahmed, ; Xue et al, ), we found a higher incidence of OLP in women (85.4%). A possible reason for this association could be that women have greater genetic, neuronal and psychological predisposition to developing depressive or anxious episodes (Ramsey et al, ).…”

Lichen planus and diabetes mellitus: Systematic review and meta‐analysis

“…The diagnostic method of DM adopted is unknown in ten articles (Barbosa et al, ; Bastos et al, ; Borghelli, Pettinari, Chuchurru, & Stirparo, ; Chung et al, ; Guggenheimer et al, ; Kövesi & Bánóczy, ; Mostafa & Ahmed, ; Saini et al, ; Sousa et al, ; Xue et al, ); five have established the diagnosis of DM by conducting the FPG test (Atefi et al, ; Denli et al, ; Mohsin, Ahmed, Fawwad, & Basit, ; Petrou‐Amerikanou et al, ; Van Dis & Parks, ). Seven articles include DM type 2 (Al‐Maweri, Ismail, Ismail, & Al‐Ghashm, ; Bastos et al, ; Cristina de Lima, Nakata, Balducci, & Almeida, ; Denli et al, ; Mohsin et al, ; Romero et al, ; Sousa et al, ), two DM type 1, and two include both DM types (Petrou‐Amerikanou et al, ; Saini et al, ).…”

“…Lichenoid reactions, clinically indistinguishable from OLP (van der Waal, ), can be induced by antihyperglycemic and antihypertensive drugs (Kaomongkolgit, ), two of the most common medications among diabetic patients. Of all the articles studied in this review, there are three (Guggenheimer et al, ; Petrou‐Amerikanou et al, ; Van Dis & Parks, ) that take into account the medication of their patients; and four studies (Mostafa & Ahmed, ; Romero et al, ; Seyhan et al, ; Xue et al, ) do not include those patients suspected of undergoing lichenoid reactions.…”

The effect of diode laser and topical steroid on serum level of TNF-alpha in oral lichen planus patients

“…A reported prevalence of 1.27% commonly in women aged between 30 and 60 years (1). In a recent study in Egypt revealed a prevalence of 1.43% among the Egyptians (2). OLP are mostly polymorphic such as reticular type which is present as white striae known as Wickham’s striae often bilateral and asymptomatic.…”