Prevalence of osteoporosis in otherwise healthy Indian males aged 50 years and above

Agrawal, N K; Sharma, Balram

doi:10.1007/s11657-012-0116-x

Cited by 52 publications

(39 citation statements)

References 31 publications

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“…Howe ver, the prevalence of VDD in Indian men is also quite high. For example, a study from Varanasi involving only men showed the prevalence of VDD to b e 58% 14 . In our study, 75% of the male subjects had either VDD or insufficiency.…”

Section: Discussionmentioning

confidence: 99%

Blood vitamin D levels in a sample population from Eastern India: a pilot study

Paul

Ray

Saha

et al. 2014

Int Jour of Biomed Res

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Section: Discussionmentioning

confidence: 99%

Blood vitamin D levels in a sample population from Eastern India: a pilot study

Paul

Ray

Saha

et al. 2014

Int Jour of Biomed Res

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“…10 Similar study by Agarwal et al found 58% vitamin D deficiency incidence rate in their study group (composed of elderly of >50 yrs). 11 Correlation of vitamin D levels with BMD was found to be statistically very significant (p value=0.000). 70.58% osteoporotic subjects were vitamin D deficient.…”

Section: Discussionmentioning

confidence: 86%

To study the bone mineral density and vitamin D in patients suffering from rheumatoid arthritis irrespective of duration in comparison to age and sex-matched controls who were not having any musculoskeletal disorder

et al. 2017

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Background: Rheumatoid arthritis is a chronic inflammatory disease of synovial tissue of joints of unknown etiology marked by a symmetric, peripheral, polyarthritis. Osteoporosis is a progressive systemic skeletal disease characterised by reduced bone mass/density and micro-architectural deterioration of bone tissue. Osteoporosis is more common in patients with rheumatoid arthritis than an age and sex-matched population. Chronic use of glucocorticoids and disability-related immobility also contributes to osteoporosis. Methods: The present study was conducted at Department of Medicine, Dr. S. N. Medical College, Jodhpur, India. Case control study was conducted to determine bone mineral densities (BMD) and vitamin D levels among patients with rheumatoid arthritis attending the medicine OPD and IPD, Dr. S. N. Medical College, Jodhpur, Rajasthan, India. 25 patients with rheumatoid arthritis and 25 age and sex-matched controls were studied. All known cases of Rheumatoid Arthritis attending Medicine outdoor and patients who are admitted indoor. Patients with co-morbidities like diabetes mellitus, coronary artery disease, hypertension, chronic kidney disease and pre-existing osteoporosis. Results: Mean age of the study population was 49.68±8.4 yrs; most of the subjects were females. Vitamin D levels were found to be comparatively lower in females. Vitamin D deficiency was more prevalent of in urban population. As the age increased the levels of vitamin D and BMD decreased. Inadequacy in vitamin D levels was more prevalent in Rheumatoid arthritis patients, 74.99% females had low BMD values. Correlation of low BMD with RA was statistically significant. The duration of Rheumatoid arthritis was related to vitamin D levels significantly (p<0.013). The longer the duration of disease more number of RA patients had vitamin D deficiency. All patients with RA for more than 4 years had osteoporosis. The duration of Rheumatoid arthritis was related to low BMD significantly (p<0.025). The correlation of HAQ (health assessment questionnaire) with BMD is statistically significant; the correlation of DAS score with RA duration is statistically significant. The correlation of DAS score with BMD is statistically significant. The lesser the BMD more number of RA patients had moderate or severe scores. Conclusions: Vitamin D levels were found to be comparatively lower in females especially in urban areas. Vitamin D deficiency and low BMD is more prevalent in Patients of rheumatoid arthritis in comparison to controls. High index of suspicion is required during follow-up of rheumatoid arthritis patients.

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“…9,10 However, in another study at Rochester, a 19%prevalence of osteoporosis has been reported, the differences in the prevalence that was seen between south Indian and north Indian subjects would have been due to many factors like genetic, nutritional, and other environmental factor which need to be looked at in further prospective studies. 11 The most dreaded complication of osteoporosis is hip fracture, which has been reported to be more in men when compared to women.…”

Section: Discussionmentioning

confidence: 93%

Study of prevalence of osteoporosis in males of above 40 years age group attending SMS Hospital, Jaipur

et al. 2017

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Background: Whenever osteoporosis is discussed, the focus is on women; men are far less likely to receive a diagnosis of osteoporosis or osteoporotic fracture because of considerable gaps in knowledge on male osteoporosis. The aim and objectives were to study the prevalence of osteoporosis in males of above 40 year age group attending SMS Hospital Jaipur & to explore the influence of various modifiable and non-modifiable risk factors on BMD.Methods: Study Location: SMS Medical College and Hospital, Jaipur. Study design: Hospital based cross sectional study. Study period: April 2015 to December 2016. Sample Size: 200. Work up: After taking ethical clearance and informed verbal consent, demographic and clinical details were noted along with S- calcium, Vitamin D and bone mineral density assessment. Osteoporosis was defined as T score ≤−2.5 bone mass −1 to −2.5 and normal as >−1. Data thus collected was analysed with help of SPSS 22.0 through frequency, percentages, Mean, SD and ANOVA.Results: Prevalence of osteopenia and osteoporosis in the study population was 28.5% and 11.5%. Age wise maximum prevalence was in the age group 71-80 years (31.81%). Prevalence of osteoporosis was more among Muslim community 20.83%, more in low socio economic group (BPL). T score of study population was -0.3705±1.41. The mean BMI, S-Calcium, Vitamin D levels and T score values among osteopenic and osteoporotic patients were statistically highly significant when compared to patients without osteo-penic/porotic changes (p<0.05).Conclusions: Osteoporosis is a silent killer and prevention is better than cure as prevention requires simple steps such as good dietary habits, active life style, good control of systemic disorders, reduced intake of tobacco and alcohol.

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Prevalence of osteoporosis in otherwise healthy Indian males aged 50 years and above

Abstract: The osteoporosis affects 8.5 % of otherwise healthy males aged 50 years and above. Vitamin D deficiency is common in such group and maybe responsible for osteoporosis.

Cited by 52 publications

References 31 publications

Blood vitamin D levels in a sample population from Eastern India: a pilot study

Blood vitamin D levels in a sample population from Eastern India: a pilot study

To study the bone mineral density and vitamin D in patients suffering from rheumatoid arthritis irrespective of duration in comparison to age and sex-matched controls who were not having any musculoskeletal disorder

Study of prevalence of osteoporosis in males of above 40 years age group attending SMS Hospital, Jaipur

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