Prevalence of osteosarcopenic obesity in community-dwelling older adults: a cross-sectional retrospective study

Kolbaşı, Esma Nur; Demirdağ, Filiz

doi:10.1007/s11657-020-00829-x

Cited by 15 publications

(13 citation statements)

References 38 publications

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“…e results allow us to hypothesize that people with obesity who show a high level of sedentary behavior and low protein intake may "evolve" to attain a state of simultaneous body composition changes, increasing the chance of 6 Journal of Obesity exhibiting worse grip strength and the consequent establishment of a vicious cycle. e prevalence of obesity + OP + low LM in this population of community-dwelling persons from 50 years was lower than most of previous investigations with osteosarcopenic obesity [14,[25][26][27][28][29][30][31][32], in which it ranged between 10% [29,30] and 31% [32]. Only Mo et al (2018) [33] referred to a similar prevalence among Chinese older females (7%) and Sasaki et al (2020) [34] showed an even lower prevalence (0.9% in older persons from the community and 4.4% in CVD patients).…”

Section: Resultscontrasting

confidence: 57%

Obesity Associated with Low Lean Mass and Low Bone Density Has Higher Impact on General Health in Middle-Aged and Older Adults

et al. 2020

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It is believed that the phenomenon of simultaneous changes in body composition could have a higher negative impact on general health. Thus, we aimed to investigate the prevalence of concomitant body composition disturbances and evaluate the association with dietary intake, sedentary behaviour, muscle strength, and performance. This is a cross-sectional study with 218 community-dwelling adults, aged 63 (59–69) years, both sexes (52% female) recruited from the Health Survey of the City of São Paulo. Assessments include appendicular lean mass (LM), fat mass and bone mineral density (BMD) by DXA, grip strength, time spent sitting, and dietary intake. Subjects were clustered into 8 groups: (1) normal, (2) osteopenia (OP), (3) low LM, (4) obesity, (5) OP + low LM, (6) obesity + OP, (7) obesity + low LM, and (8) obesity + OP + low LM. Statistical analyses include ANCOVA, the chi-square test, and linear regression models. 52 (23%) individuals presented obesity associated with another body composition change, with 14 (6%) having the combination of the 3 conditions (obesity + OP + low LM). All groups with obesity showed lower protein intake ( p ≤ 0.001 ); however, those with obesity or obesity + low LM spent more time in a sitting position ( p = 0.002 ), and the group with obesity + OP + low LM had the lowest grip strength. The combination of obesity with low LM and OP presented the aggravating factor of being associated with lower grip strength. In a context of demographic and nutrition transition, the findings represent a demand for longitudinal investigations.

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Section: Resultscontrasting

confidence: 57%

Obesity Associated with Low Lean Mass and Low Bone Density Has Higher Impact on General Health in Middle-Aged and Older Adults

et al. 2020

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“…Some other studies in older adults showed a prevalence of OSA ranging from 10 to 30%, as reviewed recently [ 11 , 12 ]. For example, a Turkish study investigated community-dwelling individuals >65 years and found a 10.7% prevalence of OSA [ 42 ]. Considering that our participants were on average much older (80.7 and 86.3 years old for women and men, respectively) and living in nursing homes, the latter known to adversely affect both body composition and nutrition [ 9 , 10 , 11 , 12 , 30 , 31 , 32 , 33 , 34 , 35 ], the prevalence of OSA was expected to be higher.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Body Composition and Dietary Intake in Nursing-Home Residents: Could Lessons Learned from the COVID-19 Pandemic Be Used to Prevent Future Casualties in Older Individuals?

et al. 2021

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The population of older adults, especially those living in the nursing homes, is growing. The sedentary lifestyle and possible poor nutrition in nursing homes place residents (NHRs) at risk for body composition impairments, malnutrition, and, subsequently, numerous chronic diseases. The aim of this study was to assess body composition (including body fluids) and dietary intake in NHRs. The association between osteosarcopenic adiposity syndrome (OSA) and its components, osteopenic adiposity (OA), sarcopenic adiposity (SA), and adiposity-only (AD), and specific macro- and micro-nutrients was evaluated as well. The study included 84 participants (82.1% women), aged 65.3–95.2 years. Body composition was assessed with an advanced bioelectrical impedance device BIA-ACC® and dietary intake was assessed via 24-h recall and analyzed using “Nutrition” software. The majority (95%) of participants were overweight with a high body fat and low muscle and bone mass, leading to a high prevalence of OSA (>50%), OA (13%), and AD (26%). There were only a few participants with SA, and they were not analyzed. The highest extracellular water/total body water ratio was observed in the OSA participants, indicating a heightened inflammatory state. Participants in all three body composition categories had a similar nutrient intake, with protein, fiber, omega-3 fatty acids, and almost all micronutrients being far below recommendations. In conclusion, a high prevalence of OSA among NHRs accompanied by a poor dietary intake, could place these residents at a very high risk for COVID-19 infections. Therefore, optimization of body composition and nutritional status should be included along with standard medical care in order to provide better health maintenance, particularly in the COVID-19 era.

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“…[ 2 ]. Globally, the prevalence of OSO in woman is 11% [ 31 ]. Multiple animal models have been used to study OSO, regarding different diets, sedentary lifestyle [ 6 , 10 ], and even hormonal restriction [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

Metformin and tBHQ Treatment Combined with an Exercise Regime Prevents Osteosarcopenic Obesity in Middle‐Aged Wistar Female Rats

Toledo-Pérez

López-Cervantes

Hernández-Álvarez

et al. 2021

Oxidative Medicine and Cellular Longevity

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Osteosarcopenic obesity (OSO) is characterized by bone density, mass, and muscle strength loss, in conjunction with adipose tissue increase. OSO impairs physical activity and mobility, provoking autonomy loss; also, it is known that augmenting body fat in the elderly decreases life expectancy. The main factors influencing this health deterioration are the inflammatory environment induced by adipose tissue and its infiltration into muscle tissue, which leads to oxidative stress generation. Currently, there are several treatments to delay OSO, among which exercise training stands out because it improves muscle fiber quality and quantity and decreases adipose tissue. We have recently demonstrated that the combined treatment between moderate exercise and metformin slows sarcopenia’s onset by a mechanism that includes adipose reduction and REDOX regulation. On the other hand, tert-butylhydroquinone (tBHQ) is a well-known antioxidant that counteracts oxidative stress. Therefore, to slow down obesity’s harmful effects on muscle mass and bone mineral density, we performed different interventions, including combining a Fartlek-type exercise routine with metformin and tBHQ administration, in a model of middle-aged female Wistar rats with obesity induced with a hypercaloric diet. Our results showed that the combined exercise-metformin-tBHQ treatment increased muscle mass and strength, decreased body weight, body mass index, and fat percentage, and improved redox status, thus increasing animal survival.

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Prevalence of osteosarcopenic obesity in community-dwelling older adults: a cross-sectional retrospective study

Cited by 15 publications

References 38 publications

Obesity Associated with Low Lean Mass and Low Bone Density Has Higher Impact on General Health in Middle-Aged and Older Adults

Obesity Associated with Low Lean Mass and Low Bone Density Has Higher Impact on General Health in Middle-Aged and Older Adults

Assessment of Body Composition and Dietary Intake in Nursing-Home Residents: Could Lessons Learned from the COVID-19 Pandemic Be Used to Prevent Future Casualties in Older Individuals?

Metformin and tBHQ Treatment Combined with an Exercise Regime Prevents Osteosarcopenic Obesity in Middle‐Aged Wistar Female Rats

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