Prevalence of pathological lesions in 161 nephrectomies: An experience from a teaching hospital in urban industrial area of Maharashtra

Chandanwale, Shirish S; Naragude, Piyusha; Singh, Madhuri; Raj, Akshi; Bamanikar, Sunita; Buch, Archana; Shah, Kushal

doi:10.4103/injms.injms_127_19

Cited by 4 publications

(3 citation statements)

References 15 publications

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“…Pyelonephritis refers to inflammation involving renal tubules, interstitium, and renal pelvis. Grossly, CPN due to vesicoureteral reflux shows polar scars and those due to obstruction, showing diffuse involvement of pyramids (13). In the present study, CPN with HDN was the most frequent non-neoplastic lesion (52%).…”

Section: Discussionsupporting

confidence: 52%

A histopathological review of nephrectomy specimens with an emphasis on pathological assessment of prognostic indicators in malignant lesions

Bhat¹,

Prasad²,

Rajeev³

et al. 2021

Biomedicine

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Introduction and Aim: Various non-neoplastic and neoplastic lesions occur in the kidney. Pathological assessment of gross and microscopic features in nephrectomy specimens is essential for diagnosis and predicts the prognosis in malignant tumours. Materials and Methods: Case records of 46 nephrectomy specimens received between two-year periods were retrieved. Detailed gross and histopathological and immunohistochemical features were studied, and malignant tumours were analysed using CAP protocol. Results: Out of 46 nephrectomy specimens, 17 were non-neoplastic and 29 neoplastic. Males constituted 32 cases and females 14 cases. The commonest non-neoplastic kidney lesion was chronic pyelonephritis with hydronephrosis (29%). The mixed epithelial and stromal tumour was the frequently encountered benign tumour (50%). Renal cell carcinoma was the most common malignant tumour in adults (70%) and Wilms tumour in children (4%). Conclusion: Histopathological examination of nephrectomy specimens helps in diagnosing, staging, and planning the management.

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Section: Discussionsupporting

confidence: 52%

A histopathological review of nephrectomy specimens with an emphasis on pathological assessment of prognostic indicators in malignant lesions

Bhat¹,

Prasad²,

Rajeev³

et al. 2021

Biomedicine

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“…In this study, more number of cases (4 cases ,7%) of xanthogranulomatous pyelonephritis were reported in a wide spectrum of age group between 20 to 80 years. Higher percentage of the case was also reported in the studies by Chandanwale et al, Awasthi et al and Ngairangbam S and Konjengbam R. [17][18][19] Only 1 case of the disease was reported in the studies by Basnet et al and Thakur et al . 4,15 One case of renal tuberculosis was seen in this study similar to that by Basnet et al 4 No case of renal tuberculosis were present in studies done by Suryawanshi et al and Bajaj et al 8,10 Only few cases of accidental discovery of isolated renal tuberculosis have been reported in the literature.…”

Section: Discussionmentioning

confidence: 53%

Histomorphological Patterns of Various Kidney Lesions in Nephrectomy Specimens: A Five Years Experience in a Tertiary Care Hospital

Sedhain,

Shrestha,

Joshi

et al. 2023

JCMC

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Background: A variety of non-neoplastic diseases and both benign and malignant neoplasms occur in the kidney. Radiological studies like ultrasound, CT and MRI are useful to provide a preoperative diagnosis, but histopathological study still remains the gold standard for definite diagnosis. This study aimed to explore the histomorphological patterns of various kidney lesions in nephrectomy specimens. Methods: This was a retrospective study conducted in the department of Pathology at College of Medical Sciences, Bharatpur, Chitwan from the period of 1st August 2017 to 31st July 2022. 57 samples of nephrectomy specimens were received during the study period of five years and were included in the study. Results: Maximum number of patients undergoing nephrectomy were in the age group of 40 to 49 years. Non neoplastic lesions constituted 87.72% of the nephrectomy specimens while the remaining were neoplastic cases. Chronic pyelonephritis was the commonest non neoplastic lesion. The commonest neoplastic lesion was renal cell carcinoma followed by transitional cell carcinoma and squamous cell carcinoma. Conclusions: Chronic pyelonephritis is a preventable cause of nephrectomy which could be avoided with early diagnosis and no operative management. The commonest malignant neoplasm was renal cell carcinoma.

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“…Therefore, it is mandatory that every nephrectomy specimen ~ 16 ~ must be studied histopathologically for clinicomorphological correlation to ensure proper management. Hence histopathology helps as a useful learning tool for the pathologist to study histomorphological spectrum of diseases [8] . In the present study analysis of 32 Nephrectomy specimens was done which included 20 non neoplastic (65%) and 12 neoplastic lesions (35%).…”

Section: Discussionmentioning

confidence: 99%

Histopathological spectrum of lesions of kidney: A morphological study

Yalavarthi,

Deshpande

et al. 2023

Int. J. Clin. Diagn. Pathol.

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Introduction:The kidneys, as essential organs with diverse functions, are of paramount importance in the human body. Their primary role involves eliminating metabolic waste products and maintaining the balance of water, salt, calcium, phosphorus, anions, and cations to uphold the plasma's acid-base equilibrium. The objective of the current study is to investigate and understand the various morphological patterns exhibited by renal diseases, as well as assess their distribution across different age groups and genders. Material and Methods: The present study was conducted at Department of Pathology, Mamata Medical College, Khammam. A total of 32 nephrectomy specimens were studied. Results:The study shows, male to female ratio is 2.5:1 with male preponderance and among 32 nephrectomy specimens 20 were non-neoplastic and 12 were neoplastic. Neoplastic lesions constitute about 20 cases with chronic pyelonephritis being the most common cause (8 cases) leading to nephrectomy. Hydronephrosis (5 cases) majority of them showed enlarged kidneys with depressed scars and loss of corticomedullary differentiation. In the age group between 5 th to 6 th decades maximum number of non-neoplastic lesions was seen and least is observed in between 1 st to 2 nd decade. Conclusion: To conclude, these findings provide valuable insights into the histopathological patterns and distribution of kidney diseases in the studied population, contributing to our understanding of the prevalence and characteristics of these conditions.

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Prevalence of pathological lesions in 161 nephrectomies: An experience from a teaching hospital in urban industrial area of Maharashtra

Cited by 4 publications

References 15 publications

A histopathological review of nephrectomy specimens with an emphasis on pathological assessment of prognostic indicators in malignant lesions

A histopathological review of nephrectomy specimens with an emphasis on pathological assessment of prognostic indicators in malignant lesions

Histomorphological Patterns of Various Kidney Lesions in Nephrectomy Specimens: A Five Years Experience in a Tertiary Care Hospital

Histopathological spectrum of lesions of kidney: A morphological study

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