BACKGROUND
The quality of medication use in older adults is suboptimal with a large percentage of individuals not receiving recommended care. Most efforts to evaluate the quality of medication use target high-risk drugs, appropriate treatment of prevalent chronic disease states, or a set of predefined quality indicators of medication use, rather than the patient. It is also suggested that racial differences in the quality of medication use may exist in older adults.
OBJECTIVE
To determine the prevalence, number, and types of medication-related problems in older adults, examining the impact of race on quality medication use.
METHODS
A prospective cohort study involving in-home interviews and medical record reviews of 200 community-residing older adults stratified by race (100 blacks, 100 whites) conducted three times over 1 year. No intervention to address medication-related problems was performed. The quality of medication use was reported as medication-related problems by clinical pharmacists.
KEY RESULTS
Mean age was 78.3 (whites) and 75.5 (blacks), with the majority being female. Although whites used more medications than blacks (11.6 versus 9.7; p < 0.01), blacks had more medication-related problems per person than whites (6.2 versus 4.9; p < 0.01). All patients had at least one medication-related problem; common problems at baseline, 6 months, and 12 months for both whites and blacks were undertreatment, suboptimal drug use, suboptimal dosing, nonadherence, and less costly alternative available. Blacks had significantly higher rates of nonadherence than whites (68% versus 42%; p < 0.01). Over the 12-month study, the number of medication-related problems not only persisted but increased (adjusted p=0.0168).
CONCLUSIONS
Medication-related problems are prevalent in both black and white older adults and persist over one-year. Blacks had more medication-related problems than whites, including higher rates of nonadherence. These findings require further study to better understand racial disparities in the quality of medication use in older adults and the impact of race on specific medication-related problems.