Prevalence of primary CNS tumors in a diagnostic setup in Nairobi, Kenya

Abstract

Introduction: Diagnosis of CNS tumors is often difficult for the general pathologist due to its rarity. However, high morbidity and mortality makes this the dreaded form of cancer and diagnosis requires precision to differentiate the various forms including secondaries. Materials and Methods: Study was conducted in an independent laboratory over a period of 6 months in Nairobi, Kenya and all primary CNS neoplasms during the study period were included in the study. Result: Amongst 42 lesions involving the CNS, 34 primary CNS neoplasms were identified. It was more common in females with a mean age of 49.41 years. Meningiomas were the most common type of CNS lesions followed by astrocytic tumors. Conclusion: Incidence of meningiomas is high in the African population. Light microscopy is essential for initial diagnosis, however, immunohistochemistry, ultrastructural studies including molecular studies are essential to predict further management.

Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study

“…Meningiomas and gliomas accounted for most of the adult BTs, with a cumulative prevalence of 79.1%. This is like other studies, both locally [ 31 , 43 ] and globally [ 32 , 33 , 44 ]. Most adult tumors were benign, with meningiomas being the most frequent.…”