Prevalence of Probable Mental Disorders Among Pediatric Asthma Patients in an Inner-City Clinic

Goodwin, Renée D.; Messineo, Kathryn; Bregante, Audrey C.; Hoven, Christina W.; Kairam, Ram

doi:10.1080/02770900500264770

Cited by 75 publications

(67 citation statements)

References 36 publications

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“…Contrary to our conclusions, several prior cross-sectional studies showed that probable PD, including anxiety or depression symptoms, was not significantly associated with higher levels of medical services for asthma (10,30,31). However, the cross-sectional study design and possible recall bias may weaken the validity of these cross-sectional studies.…”

Section: Discussioncontrasting

confidence: 55%

Co-morbid psychological dysfunction is associated with a higher risk of asthma exacerbations: a systematic review and meta-analysis

Zhang

Zheng³

et al. 2016

J. Thorac. Dis.

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Background:The longitudinal associations between psychological dysfunction (PD) and asthma exacerbations (AE) have not been adequately addressed. This study aimed to systematically assess the influence of PD on AE, and to determine whether different PD affects AE differentially. P<0.001], presenting as hospitalizations (RR adj =1.22, 95% CI: 1.12-1.34, P<0.001), unscheduled doctor visits (RR =4.26, 95% CI: 2.52-7.19), and emergency department (ED) visits (RR adj =1.06, 95% CI: 1.01-1.10, P=0.009) because of asthma. Depression significantly increased the risk of AE (RR adj =1.07, 95% CI: 1.04-1.11, P<0.001), presenting as hospitalizations (RR adj =1.26, 95% CI: 1.07-1.49, P=0.007) and ED visits (RR adj =1.06, 95% CI: 1.02-1.11, P=0.007) because of asthma. Anxiety was only associated with an increased risk of AE in pregnant women (RR =1.05, 95% CI: 1.01-1.08), possibly due to the small amount of data available on anxiety. The influence of PD on AE was only significant when the PD exposure time exceeded one year.Conclusions: Co-morbid PD adversely affects AE, and there are differential effects of depression and anxiety. Asthmatic subjects with PD may benefit from more attention when establishing a treatment regimen in clinical practice.

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Section: Discussioncontrasting

confidence: 55%

Co-morbid psychological dysfunction is associated with a higher risk of asthma exacerbations: a systematic review and meta-analysis

Zhang

Zheng³

et al. 2016

J. Thorac. Dis.

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“…The WHO estimates that there are currently 300 million people suffering from asthma and asthma is also estimated to account for ,250,000 deaths per year worldwide [12,13]. Asthma can have a significant effect on quality of life, and consequences include sleeplessness, daytime fatigue, reduced activity levels, school and work absenteeism, and mental health problems [14][15][16]. It is hypothesised that asthma is a risk factor associated with suicidal behaviour.…”

mentioning

confidence: 99%

Asthma and suicide-related adverse events: a review of observational studies

Iessa¹,

Murray²,

Curran³

et al. 2011

Eur Respir Rev

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Suicide is a major public health concern. There are several risk factors associated with suicide. Chronic illnesses, such as asthma, have been linked to an increased risk of suiciderelated events. This study reviews the evidence of an association between asthma and suicide using published epidemiological observational studies.An electronic search using PubMed and EMBASE was performed. Studies that investigated the association of asthma with suicide-related behaviour were selected. Studies were examined to form a descriptive analysis.Six observational studies met the selection criteria, of which at least one suicide-related adverse event was studied. Three studies investigated completed suicide, two suicide attempts and four suicide ideation. Two of the studies focused on individuals aged ,18 yrs.Evidence from observational data support the hypothesis of an association between asthma and suicide-related behaviour (ideation, attempts and completion); however, epidemiological studies, with more objective measures and larger sample sizes, adjusting for a wider scope of suicide-related confounding factors (e.g. comorbidities), and with a longitudinal design, are needed for a more conclusive answer.

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“…Asthma and PD are both characterized by acute episodes, salient respiratory symptoms and anxiety with avoidance of situations related to acute attacks (Klein, 1993;Yellowlees and Kalucy, 1990). There is a significantly higher (6.5 to 24%) prevalence of PD in asthmatics (Goodwin et al, 2005;Shavitt et al, 1992;Yellowlees et al, 1988) than the 1-3% reported in the general population (Kessler et al, 2006;Weissman, 1988). Perna et al (1997) found a significantly higher prevalence of PD, sporadic panic attacks, and social phobia in asthmatics than the general population.…”

Section: Panic and Comorbid Conditionsmentioning

confidence: 69%

Lifelong Opioidergic Vulnerability Through Early Life Separation: A Recent Extension of the False Suffocation Alarm Theory of Panic Disorder

Preter¹

2016

Panic Disorder

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We briefly reference previous material on Klein's suffocation false alarm theory (SFA) of panic disorder (Klein, 1993) and its amplification in 2008 (Preter andKlein, 2008). We then discuss a recent finding showing a fundamental difference in opioidergic reactivity to a naloxone challenge in psychiatrically and medically healthy adults, based on the presence or absence of childhood separation/parental loss.In 1993, Klein published the original SFA theory of panic disorder (Klein, 1993), attempting to integrate the multiplicity of apparently unrelated clinical and laboratory observations. We posited "that a physiologic misinterpretation by a suffocation monitor misfires an evolved suffocation alarm system. This produces sudden respiratory distress followed swiftly by a brief hyperventilation, panic, and the urge to flee. Carbon dioxide hypersensitivity is seen as due to the deranged suffocation alarm monitor. If other indicators of potential suffocation provoke panic, this theoretical extension is supported." In the original paper, we tested "the theory by examining Ondine's curse as the physiologic and pharmacologic converse of panic disorder, splitting panic in terms of symptomatology and challenge studies, reevaluating the role of hyperventilation, and reinterpreting the contagiousness of sighing and yawning, as well as mass hysteria." (Klein, 1993) Original SFA focused on relating the observed lactate and carbon dioxide hypersensitivity in panic disorder to a putative dysfunction in a hypothesized suffocation alarm. At the time, the underlying pathophysiology that might connect the apparent disparate "phenomena of panic during relaxation and sleep, late luteal phase dysphoric disorder, pregnancy, childbirth, pulmonary disease, separation anxiety, and treatment", was unknown.

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Prevalence of Probable Mental Disorders Among Pediatric Asthma Patients in an Inner-City Clinic

Cited by 75 publications

References 36 publications

Co-morbid psychological dysfunction is associated with a higher risk of asthma exacerbations: a systematic review and meta-analysis

Co-morbid psychological dysfunction is associated with a higher risk of asthma exacerbations: a systematic review and meta-analysis

Asthma and suicide-related adverse events: a review of observational studies

Lifelong Opioidergic Vulnerability Through Early Life Separation: A Recent Extension of the False Suffocation Alarm Theory of Panic Disorder

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