Prevalence of Pulmonary Hypertension in Limited and Diffuse Scleroderma

Battle, Robert W.; Davitt, Martha A.; Cooper, Sheldon M.; Buckley, Lenore M.; Leib, Edward S.; Beglin, Peter A.; Tischler, Marc D.

doi:10.1378/chest.110.6.1515

Cited by 142 publications

(75 citation statements)

References 19 publications

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“…In a Canadian prospective study, only 4.9% of SSc patients were diagnosed as having PAH using Doppler echocardiography (2). Similar surveys in the UK found prevalences of 13% and 12% (3,9), and surveys in the US found prevalences of 35% and 38.6% (19,20). This variation is probably due to differences in the definition of PAH and in the populations of patients studied.…”

Section: Prevalence Of Undiagnosed Pah In Community Practicesmentioning

confidence: 96%

The prevalence of undiagnosed pulmonary arterial hypertension in subjects with connective tissue disease at the secondary health care level of community‐based rheumatologists (the UNCOVER study)

Wigley

Lima

Mayes

et al. 2005

Arthritis & Rheumatism

170

103

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Objective. Most of the data about the prevalence of pulmonary arterial hypertension (PAH) are from tertiary centers that are biased toward seeing more severe cases; therefore, the true prevalence of PAH among patients with connective tissue disease is unknown. We sought to determine the point prevalence of undiagnosed PAH in community-based rheumatology practices.Methods. The study design was a multicenter, prospective and retrospective survey and analysis of clinical cases in 50 community rheumatology practices. We evaluated a total of 909 patients with either scleroderma ( Conclusion. A significant number of patients with SSc or MCTD (13.3%) followed up in a community rheumatology practice setting have undiagnosed elevated ERVSP consistent with PAH.

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Section: Prevalence Of Undiagnosed Pah In Community Practicesmentioning

confidence: 96%

The prevalence of undiagnosed pulmonary arterial hypertension in subjects with connective tissue disease at the secondary health care level of community‐based rheumatologists (the UNCOVER study)

Wigley

Lima

Mayes

et al. 2005

Arthritis & Rheumatism

170

103

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“…It is now realized that secondary pulmonary hypertension is relatively common and is a particular problem in connective tissue disease [1]. Furthermore, new treatment options are available and prostacyclin and its derivatives have been shown to be beneficial long-term therapy for some patients [2], including those with severe pulmonary hypertension in association with connective tissue disease [3,4].…”

mentioning

confidence: 99%

Pulmonary artery pressure measurement during exercise testing in patients with suspected pulmonary hypertension

Raeside¹,

Smith²,

Brown³

et al. 2000

Eur Respir J

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It is recognized that exercise produces abnormally large increases in pulmonary artery pressure in patients with pulmonary vascular disease as a consequence of a variety of disorders, but the relationship between pressure and cardiopulmonary exercise performance is poorly understood. This lack of understanding is due (in part) to difficulty making measurements of pulmonary haemodynamics using conventional fluid filled catheters. This article seeks to improve understanding by comparing variables measured during formal exercise testing with simultaneous measurements of pulmonary artery pressure using a micro-manometer tipped catheter.Ten patients with suspected pulmonary hypertension were studied using a micromanometer tipped pulmonary artery catheter, during cardiopulmonary exercise testing.Ventilatory equivalents for oxygen and carbon dioxide correlated with the pulmonary artery pressure measured on exercise, but oxygen pulse and oxygen uptake did not. Ventilatory equivalents, noninvasively measured during exercise, may merit further study as potential surrogates of pulmonary artery pressure and hence be useful in identifying individuals at risk of developing pulmonary hypertension. Eur Respir J 2000; 16: 282±287.

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“…A primeira série de casos de pacientes com ES e HP foi descrita por Sackner em 1964 (19) ; a partir daí outras séries foram descritas na literatura (14,16,(20)(21)(22)(23)(24)(25)(26) (Tabela 6). A comparação dos achados do presente estudo com outros da literatura se torna difícil em razão das diferenças entre as populações estudadas, a metodologia empregada para a investigação da HP e os critérios utilizados para definir a sua presença.…”

Section: Tabela 5 Características Clínicas E Laboratoriais Dos Pacienunclassified

“…A comparação dos achados do presente estudo com outros da literatura se torna difícil em razão das diferenças entre as populações estudadas, a metodologia empregada para a investigação da HP e os critérios utilizados para definir a sua presença. Os estudos que utilizaram o cateterismo (CAT) de ventrículo direito para diagnóstico demonstraram uma prevalência de 5% a 12%, enquanto aqueles que empregaram o ECO revelaram taxas de prevalência mais alta, entre 13% e 35% (14,16,(19)(20)(21)(22)(23)(24)(25) .…”

Section: Tabela 5 Características Clínicas E Laboratoriais Dos Pacienunclassified

Avaliação da prevalência de hipertensão pulmonar na esclerose sistêmica

Azevedo¹,

Sampaio-Barros²,

Torres³

et al. 2004

Rev. Bras. Reumatol.

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Prevalence of Pulmonary Hypertension in Limited and Diffuse Scleroderma

Cited by 142 publications

References 19 publications

The prevalence of undiagnosed pulmonary arterial hypertension in subjects with connective tissue disease at the secondary health care level of community‐based rheumatologists (the UNCOVER study)

The prevalence of undiagnosed pulmonary arterial hypertension in subjects with connective tissue disease at the secondary health care level of community‐based rheumatologists (the UNCOVER study)

Pulmonary artery pressure measurement during exercise testing in patients with suspected pulmonary hypertension

Avaliação da prevalência de hipertensão pulmonar na esclerose sistêmica

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