2010
DOI: 10.1016/j.inhe.2010.03.004
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Prevalence of rubella IgG antibodies among pregnant women in Zaria, Nigeria

Abstract: Rubella is a vaccine-preventable viral infection which in pregnancy can lead to foetal wastage and congenital malformations. A rubella IgG serosurvey of 430 consenting pregnant women attending the antenatal clinic was conducted at the Ahmadu Bello University Teaching Hospital, Zaria between 1 May 2007 and 29 February 2008. Questionnaires were also used to assess their level of awareness and pregnancy outcomes noted. Of the 430 serum samples tested, 421 (97.9%) were positive and 9 (2.1%) were negative for rubel… Show more

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Cited by 22 publications
(24 citation statements)
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“…Our 351 finding of no statistically significant increases in rubella antibody seroprevalence with increasing age (after 352 approximately 15 years of age) has been observed in a number of the above-mentioned serosurveys and others 353 [34, 35, 39, 42-46, 48, 49, 53, 54]. Moreover, in agreement with published observations from other African 354 countries, for the assessment population in DRC overall, rubella antibody seroprevalence was similar among 355 19 women declaring residence in urban versus rural settings; however, differences in antibody seroprevalence were 356 observed between different geographic areas in the country [31,34,38,41,43,44,46,51]. Last and consistent 357 with reports from other African countries, age at first pregnancy, number of pregnancies, civil status, 358 educational level, and occupation were not associated with rubella antibody seroprevalence in DRC [34, 38, 41, 359 44-46, 53].…”
supporting
confidence: 70%
See 1 more Smart Citation
“…Our 351 finding of no statistically significant increases in rubella antibody seroprevalence with increasing age (after 352 approximately 15 years of age) has been observed in a number of the above-mentioned serosurveys and others 353 [34, 35, 39, 42-46, 48, 49, 53, 54]. Moreover, in agreement with published observations from other African 354 countries, for the assessment population in DRC overall, rubella antibody seroprevalence was similar among 355 19 women declaring residence in urban versus rural settings; however, differences in antibody seroprevalence were 356 observed between different geographic areas in the country [31,34,38,41,43,44,46,51]. Last and consistent 357 with reports from other African countries, age at first pregnancy, number of pregnancies, civil status, 358 educational level, and occupation were not associated with rubella antibody seroprevalence in DRC [34, 38, 41, 359 44-46, 53].…”
supporting
confidence: 70%
“…Therefore, during the years before introducing RCV, 380 20 DRC will need to a) focus efforts on improving the delivery of measles vaccination, thereby creating a successful 381 platform on which to introduce rubella vaccination; b) establish an integrated nationwide measles-rubella 382 surveillance system as well as, at least, sentinel sites for CRS surveillance; and c) use best practices from measles 383 vaccination campaigns to assure a high-quality rubella wide-age campaign. Moreover, as found in two Nigerian 384 studies, awareness of rubella virus infection in DRC is probably low; therefore, increased public awareness of 385 CRS should accompany RCV introduction [44,46]. According to this report, a significant proportion of WCBA in 386 DRC (including adolescent girls in whom pregnancies at age 12 years are recorded in DRC's ANC site data) are 387 susceptible to rubella virus infection and must be considered in the country's RCV introduction.…”
mentioning
confidence: 94%
“…Maternal IgM was detected in some studies as a marker of recent or current infection, which is associated with an increased risk of vertical transmission. The range of maternal susceptibility to Rubella was 2.1% to 43% in pregnant women [186,189] and 21.1% -71.04% in women with BOH [91,190]. Higher susceptibility rates were reported [1,91,93,178,209,210] in Nigeria (84.8%), India (71%), Nepal (50%), Brazil (28.4%), Iran (25%), and Sri Lanka (24%).…”
Section: Rubella Virusmentioning
confidence: 99%
“…We identified over 220 studies that provided cross‐sectional data and nearly 180 studies that reported on immunity for women of child‐bearing age, primarily for rubella. Table summarizes the over 400 cross‐sectional and women of child‐bearing age measles and rubella serological studies…”
Section: Resultsmentioning
confidence: 99%