Prevalence of sarcopenic obesity in adults with end-stage knee osteoarthritis

Godziuk, Kristine; Prado, Carla M.; Woodhouse, Linda J.; Forhan, Mary

doi:10.1016/j.joca.2019.05.026

Cited by 38 publications

(35 citation statements)

References 46 publications

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“…Despite decades of efforts to slow down the progress of the epidemic, 39% of the world's people are obese or overweight at the present time 2. The main problem is that obesity is not limited to a certain period of age or to one group of people, but it is common among people of all ages and ethnic groups, leading to an increase of other diseases such as cardiovascular disease, hypertension, osteoarthritis, type 2 diabetes and dyslipidaemia 3–6…”

Section: Introductionmentioning

confidence: 99%

Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis

Zhong

Luo

Yang

et al. 2020

Postgraduate Medical Journal

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Obesity is a growing chronic health problem worldwide. Studies about acupuncture for obesity treatment are many. But there are some doubts about the effectiveness of acupuncture versus sham acupuncture in treating obesity due to its lack of medical evidence. Therefore, the aim of this study is to assess the efficacy of acupuncture for obesity treatment and provide clinic evidence. Four English databases (PubMed, EMBASE, Web of Science and Cochrane Central Register of Controlled Trials) and four Chinese databases (China National Knowledge Infrastructure, Chinese BioMedical Database, Chinese Scientific Journal Database and Wan-Fang Data) were searched from their receptions to August 2019. Randomized controlled trials (RCTs) using the comparison between acupuncture and sham acupuncture to treat simple obesity were included. The primary outcome of body mass index (BMI) would be used to measure the effect of acupuncture on obesity. According to the trial data extraction form based on the Cochrane Handbook, two reviewers separately extracted the data. Risk of bias of the RCTs was assessed by the Cochrane Risk of Bias Tool. The study included 8 RCTs with 403 patients. When compared with sham acupuncture, acupuncture showed obviously effect in BMI reduction (MD=1.0kg/m2, 95% CI=0.6 to 1.4, P<0.001). There was also significant reduction in body weight (MD=1.85kg, 95%CI=0.82 to 2.88, p<0.001), WC (MD=0.97cm, 95%CI=0.24 to 1.71, p=0.01) and body fat mass percentage (MD=1.01, 95%CI=0.25 to 1.77, p<0.05). However, WHR (MD=0.01, 95%CI=0 to 0.03, p>0.05) was not statistically and significantly different between the acupuncture and control groups. Adverse effects were reported in 3 studies. The review suggests that acupuncture is an effective therapy for simple obesity rather than a placebo effect. This potential benefit needs to be further evaluated by longer-term and more rigorous RCTs.

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Section: Introductionmentioning

confidence: 99%

Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis

Zhong

Luo

Yang

et al. 2020

Postgraduate Medical Journal

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“…Another possible limitation of our study is the size of the sample analyzed. However, considering the prevalence of severe obesity in the world population, the number of individuals recruited is considerable, given that other previous studies on this subject have a similar sample size to that of our study [14,18].…”

Section: Discussionmentioning

confidence: 90%

“…Sarcopenic obesity, characterized by simultaneous muscle mass loss and increased body fat, has been recognized as a condition that requires greater clinical attention due to the unfavorable outcomes that can lead to disability, difficulty in carrying out daily activities, and increased mortality [ 13 – 15 ]. Despite the clinical importance of the two simultaneous conditions, obesity and sarcopenia-related parameters, few studies have analyzed this conditions in middle-aged adults [ 16 , 17 ] and mainly in severely obese individuals [ 14 , 18 ]. Previous research suggests that poor nutrition is an underlying cause of sarcopenia and that dietary interventions may prevent or treat the loss of muscle mass and strength [ 6 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

What are the factors associated with sarcopenia-related variables in adult women with severe obesity?

et al. 2020

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Background: Understanding the association between sarcopenia-related variables and several risk factors may help to implement interventions aimed at preventing its occurrence by reducing or controlling the identified risk factors. Although changes in body composition occur in both sexes, in women, muscle loss is accentuated due to decreased estrogen levels following menopause. This study aims to determine the factors associated with sarcopenia-related parameters in middle-aged women identified with class II/III obesity (body mass index [BMI] ≥ 35 kg/m 2). Methods: The study included 104 women with severe obesity (40.23 ± 8.49 years) with an average body fat percentage of 52.45 ± 4.14%. Sarcopenia was assessed using total appendicular skeletal muscle mass (ASMM), appendicular skeletal muscle mass index (ASMMI), and appendicular skeletal muscle mass adjusted by BMI (ASMM/BMI) as evaluated using dual energy X-ray absorptiometry (DXA). Hand grip strength (HGS) and HGS adjusted by BMI (HGS/BMI) were evaluated using dynamometry. Functional performance was assessed using the walking speed test (WS). The explanatory variables were age, lifestyle, comorbidities, food consumption, and metabolic parameters. A multivariate linear regression was performed. Results: Factors associated with sarcopenia-related variables in 104 severely obese women with a mean BMI of 43.85 kg/ m 2 were as follows: ASMMI negatively correlated with serum levels of tetraiodothyronine (T4) and tobacco use; ASMM/ BMI negatively correlated with age, serum T4 levels, and diabetes; ASMM negatively correlated with T4 serum levels and diabetes; HGS negatively correlated with age and hypercholesterolemia, and positively correlated with low-density lipoprotein cholesterol (LDL-c); HGS/BMI negatively correlated with age and hypercholesterolemia and positively correlated with LDL-c; and WS negatively correlated with hypothyroidism and diabetes. Conclusion: In severely obese women, muscle mass and function were inversely associated with age, smoking status, endocrine parameters, hypercholesterolemia, and comorbidities such as diabetes. Thus, the results of this investigation are relevant in supporting the development of clinical interventions to aid in the prevention of sarcopenia in adult women with severe obesity.

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“…Thus, a taller person is most likely to have a higher ankle torque [33]. Other research also reports that a higher BMI person has shorter strides [34]; thus, if that person walks at the same walking speed as another person with lower BMI, the shorter stride length will result in higher ankle velocity. Compromise all this information leads to the possibility of a relationship between ankle velocity and BMI.…”

Section: Results Of Ankle Velocity Reference Estimationmentioning

confidence: 97%

Improving Passive Ankle Foot Orthosis System Using Estimated Ankle Velocity Reference

Adiputra¹,

Rahman

Ubaidillah

et al. 2020

IEEE Access

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This study aims to investigate an appropriate ankle velocity reference (ωref), which is the average ankle velocity of a certain healthy subject when walking with a certain walking speed. The goal is to improve a Passive Controllable Ankle Foot Orthosis (PICAFO) by implementing the ankle velocity reference. Firstly, the function to estimate ωref, based on walking speed and body mass index (BMI), is obtained from 16 able-bodied subjects walking gait data. The effect of controlled stiffness (based on ωref) to the user's ankle kinematics and muscle activity was evaluated by comparing it to other settings, such as walking barefooted and various constant damping stiffness (0%, 30%, 60%, and 100% of the maximum damping stiffness). Two able-bodied subjects (normal and overweight) participated in the evaluation, where they had to walk at two different walking speeds (1 and 2 km/h). The result showed that ankle kinematics and muscle activity were improved when ω was controlled during walking speed of 1 km/h for both subjects. In terms of ankle kinematics, the toe clearance occurred, and walking stability increased. In terms of muscle activity, the average muscle activity had reduced by ~29% for the normal subject and by ~57% for an overweight subject, which shows that PICAFO provides necessary damping stiffness to replace the muscle works partially. In the future, by using the ωref based on walking speed and BMI, the therapists can skip the trial and error process of finding an appropriate PICAFO prescription for a post-stroke patient.

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Prevalence of sarcopenic obesity in adults with end-stage knee osteoarthritis

Cited by 38 publications

References 46 publications

Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis

Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis

What are the factors associated with sarcopenia-related variables in adult women with severe obesity?

Improving Passive Ankle Foot Orthosis System Using Estimated Ankle Velocity Reference

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