Prevalence of SARS-CoV-2 Among Patients Admitted for Childbirth in Southern Connecticut

Campbell, Katherine; Tornatore, Jean M; Lawrence, Kirsten E; Illuzzi, Jessica L.; Sussman, L. Scott; Lipkind, Heather S.; Pettker, Christian M.

doi:10.1001/jama.2020.8904

Cited by 104 publications

(114 citation statements)

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“…Reported rates of preterm birth have ranged between 18% and 43%, and neonatal pneumonia has been documented in up to 30%, although a systematic review estimated a lower rate of 8%, 28 and many cases of neonatal respiratory infection were reported as “not due to COVID-19.” 8 , 28 The rate of preterm births is potentially higher than previously documented in MERS and SARS-CoV (27% and 25%, respectively), while IUGR rates are comparable (9% vs 9% and 13% in MERS and SARS-CoV, respectively). 9 A significant proportion of the preterm births reported in case series appear to be performed in order to protect maternal respiratory function. There were few miscarriages, stillbirths or neonatal deaths (2% or less; Tables 1 and 2 ).…”

Section: Pregnancy and Neonatal Outcomes Following Covid-19 Infectionmentioning

confidence: 99%

“… 8 In contrast to SARS and MERS, there appears to be a cohort of minimally symptomatic or even asymptomatic individuals who carry COVID-19, some of whom may be pregnant women. 9 , 10 However, due to the fact that COVID-19 pneumonia can cause rapidly progressive diffuse bilateral interstitial lung disease, there is a potentially high risk of respiratory decompensation and hypoxaemic respiratory failure in symptomatic pregnant women, 11 which likely contributes to the emerging increased risk of critical care admission in pregnant women with COVID-19. 12…”

Section: Introductionmentioning

confidence: 99%

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MS, pregnancy and COVID-19

et al. 2020

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Concerns regarding infection with the novel coronavirus SARS-CoV-2 leading to COVID-19 are particularly marked for pregnant women with autoimmune diseases such as multiple sclerosis (MS). There is currently a relative paucity of information to guide advice given to and the clinical management of these individuals. Much of the limited available data around COVID-19 and pregnancy derives from the obstetric literature, and as such, neurologists may not be familiar with the general principles underlying current advice. In this article, we discuss the impact of potential infection on the pregnant woman, the impact on her baby, the impact of the current pandemic on antenatal care, and the interaction between COVID-19, MS and pregnancy. This review provides a framework for neurologists to use to guide the individualised advice given to both pregnant women with MS, and those women with MS who are considering pregnancy. This includes evidence derived from previous novel coronavirus infections, and emerging evidence from the current pandemic.

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Section: Pregnancy and Neonatal Outcomes Following Covid-19 Infectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

MS, pregnancy and COVID-19

et al. 2020

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“…Specifically, while the benefits of universal SARS-CoV-2 testing on labor and delivery units to optimize staff and patient safety have been published, the impact of a universal SARS-CoV-2 testing program on maternal stress or anxiety has not been reported. [1][2][3] In addition to the toll of SARS-CoV-2 on obstetric patients' psychological experiences, health care workers exposed to SARS-CoV-2 are also at increased risk for symptoms of depression, anxiety, insomnia, and distress. 4 Data from past outbreaks suggest that clear communication, access to adequate personal protective equipment (PPE), and adequate rest and support may mitigate these ill effects.…”

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confidence: 99%

The Psychological Experience of Obstetric Patients and Health Care Workers after Implementation of Universal SARS-CoV-2 Testing

et al. 2020

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Objective This study was aimed to describe the hospitalization and early postpartum psychological experience for asymptomatic obstetric patients tested for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) as part of a universal testing program and report the impact of this program on labor and delivery health care workers' job satisfaction and workplace anxiety. Study Design This is a cohort study of asymptomatic pregnant women who underwent SARS-CoV-2 testing between April 13, 2020 and April 26, 2020. Semistructured interviews were conducted via telephone at 1 and 2 weeks posthospitalization to assess maternal mental health. Depression screening was conducted using the patient health questionnaire-2 (PHQ-2). An online survey of labor and delivery health care workers assessed job satisfaction and job-related anxiety before and during the novel coronavirus disease 2019 (COVID-19) pandemic, as well as employees' subjective experience with universal testing. Patient and employee responses were analyzed for recurring themes. Results A total of 318 asymptomatic women underwent SARS-CoV-2 testing during this 2-week period. Six of the eight women (75%) who tested positive reported negative in-hospital experiences secondary to perceived lack of provider and partner support and neonatal separation after birth. Among the 310 women who tested negative, 34.4% of multiparous women reported increased postpartum anxiety compared with their prior deliveries due to concerns about infectious exposure in the hospital and lack of social support. Only 27.6% of women, tested negative, found their test result to be reassuring. Job satisfaction and job-related anxiety among health care workers were negatively affected. Universal testing was viewed favorably by the majority of health care workers despite concerns about delays or alterations in patient care and maternal and neonatal separation. Conclusion Universal testing for SARS-CoV-2 in obstetric units has mixed effects on maternal mental health but is viewed favorably by labor and delivery employees. Ongoing evaluation of new testing protocols is paramount to balance staff and patient safety with quality and equality of care. Key Points

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“…In den Hotspot-Regionen New York City und London wiesen systematische Screeninguntersuchungen in Entbindungskliniken 7-15 % SARS-CoV-2-positive Schwangere nach, die in bis zu 89 % asymptomatisch waren [16,17]. In Regionen mit niedrigeren COVID19 Erkrankungsraten wie in Connecticut (USA) fand sich im April 2020 bei Schwangeren dagegen nur eine Prävalenz von < 3 % -wiederum über 70 % davon waren asymptomatisch [18]. Erste deutsche Daten im gleichen Zeitraum beschreiben eine vergleichbar niedrige Periodenprävalenz von 0,6 % (95 %-CI 0,01-3,1 %) [19].…”

Section: Sars-cov-2/covid-19 Prävalenz Bei Schwangerenunclassified

Aktualisierte Empfehlungen zu SARS-CoV-2/COVID-19 und Schwangerschaft, Geburt und Wochenbett

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Hagenbeck

Hecher

et al. 2020

Z Geburtshilfe Neonatol

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ZusammenfassungMit Beginn der SARS-CoV-2 Pandemie haben die deutschen geburtshilflichen und pädiatrischen Fachgesellschaften im März 2020 Empfehlungen zur Versorgung infizierter Schwangerer und deren Neugeborener, wie auch notwendige Schutzmaßnahmen für das Personal veröffentlicht [1–3]. Eine Aktualisierung ist aufgrund des rasanten Wissenszuwachses notwendig. Die vorliegende Empfehlung versteht sich daher als Fortschreibung der bereits vorliegenden Publikationen [1–3].Von der Cochrane Pregnancy and Childbirth Group wurden weltweit nationale Empfehlungen verglichen und als Review veröffentlicht [4]. In methodischer Anlehnung hieran nehmen die vorliegenden aktualisierten Empfehlungen Stellung zu den Kernfragen der prä-, peri- und postnatalen Betreuung bei SARS-CoV-2 und COVID-19, auf der Grundlage der bis zum 30.05.2020 verfügbaren Publikationen. Die Stellungnahmen basieren auf einem sorgfältig abgestimmten ExpertInnenkonsens und können sich – insofern neue Erkenntnisse veröffentlicht werden – zeitnah ändern.Die Verantwortung für das konkrete Vorgehen bleibt bei dem vor Ort medizinisch betreuenden Team, dessen Entscheidungen durch diese Empfehlung unterstützt werden sollen.

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Prevalence of SARS-CoV-2 Among Patients Admitted for Childbirth in Southern Connecticut

Abstract: C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA.

Cited by 104 publications

References 1 publication

MS, pregnancy and COVID-19

MS, pregnancy and COVID-19

The Psychological Experience of Obstetric Patients and Health Care Workers after Implementation of Universal SARS-CoV-2 Testing

Aktualisierte Empfehlungen zu SARS-CoV-2/COVID-19 und Schwangerschaft, Geburt und Wochenbett

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