2021
DOI: 10.1016/j.jiph.2021.06.001
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Prevalence of SARS-CoV-2 infection and dynamics of antibodies response among previously undiagnosed healthcare workers in a university hospital: A prospective cohort study

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Cited by 9 publications
(13 citation statements)
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“…Here, we evaluated the correlation between Ortho Clinical assay and neutralizing antibodies to set cut-off values of this assay to predict the level of antibody neutralization. Interestingly, we have demonstrated a correlation of Ortho Clinical IgG/total Ig against spike-1 of SARS-CoV-2 virus assay with the neutralizing assay in agreement with other studies using anti-spike protein assays ( Šimánek et al., 2021 ; Salazar et al., 2020 ; Suhandynata et al., 2021 ; Musa et al., 2021 ). Subsequently, we assessed the ability of our serology assay to predict the presence of neutralizing antibodies and to establish a high titer of 1:160 using ROC curves.…”
Section: Discussionsupporting
confidence: 91%
“…Here, we evaluated the correlation between Ortho Clinical assay and neutralizing antibodies to set cut-off values of this assay to predict the level of antibody neutralization. Interestingly, we have demonstrated a correlation of Ortho Clinical IgG/total Ig against spike-1 of SARS-CoV-2 virus assay with the neutralizing assay in agreement with other studies using anti-spike protein assays ( Šimánek et al., 2021 ; Salazar et al., 2020 ; Suhandynata et al., 2021 ; Musa et al., 2021 ). Subsequently, we assessed the ability of our serology assay to predict the presence of neutralizing antibodies and to establish a high titer of 1:160 using ROC curves.…”
Section: Discussionsupporting
confidence: 91%
“…Our results concur well with the 15.8 and 19.9% of prevalence of SARS-CoV-2 infection among healthcare workers founded in Kasr Al-Aini University Hospital, Cairo University, and Hospital Universitario de Fuenlabrada, respectively. 24 , 25 Reports from various countries show different seroprevalence of SARS-CoV2 patterns among healthcare workers (HCWs), with an 8.7% in the meta-analysis by Galanis et al, being higher in studies conducted in North America (12.7%) compared to those in Europe (8.5%), Africa (8.2%) and Asia (4%). 26 …”
Section: Discussionmentioning
confidence: 99%
“…A further 1357 articles were removed after title and abstract screening and 21 articles were removed after review of full-texts. Finally, 24 articles were included in the scoping review [ [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] ]. The characteristics and salient findings of the included studies are summarised in Table 1 , Table 2 , Table 3 , grouped broadly as SARS-CoV-2 seropositivity studies, outbreak investigations and studies on mental health.…”
Section: Resultsmentioning
confidence: 99%
“…This was not observed for other occupations in the academic medical health system. Shepard, 2021 [ 25 ] United States Retrospective analysis Environmental services workers (56.12% females, average age 43.18 years), n=335 In an academic medical centre, there was a significantly greater prevalence of COVID-19 rt-PCR test positivity among environmental services workers (5.96%) compared to clinicians (1.93%; P<0.0001) and nurses (1.46%; P<0.0001). Shields, 2020 [ 26 ] United Kingdom Cross-sectional study Housekeeping staff, n=29 In a large hospital trust, the seroprevalence of SARS-CoV-2 antibodies was highest among housekeeping staff (34.5%, 10 out of 29 tested positive), compared to other asymptomatic healthcare workers.…”
Section: Resultsmentioning
confidence: 99%
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