Prevalence of selected birth defects by maternal nativity status, United States, 1999–2007

Kirby, Russell S.; Cara, T.; Wingate, Martha S.; Janević, Teresa; Copeland, Glenn; Flood, Timothy J.; Isenburg, Jennifer; Canfield, Mark A.

doi:10.1002/bdr2.1489

Cited by 15 publications

(10 citation statements)

References 38 publications

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“…Previous research has shown variation in prevalence of this gene among different racial/ethnic groups, in which a C to T mutation at nucleotide 677 is a risk factor for cardiovascular defects and NTDs (Franco, Araújo, Guerreiro, Elion, & Zago, ; Wilken et al, ). Additionally, sociodemographic factors such as nativity, individual socioeconomic status, and neighborhood were not further explored, but may also impact the prevalence of birth defects (Kirby et al, ; Shumate, Hoyt, Liu, Kleinert, & Canfield, ).…”

Section: Discussionmentioning

confidence: 99%

The prevalence of birth defects among non‐Hispanic Asian/Pacific Islanders and American Indians/Alaska Natives in Texas, 1999–2015

Shumate

Hoyt

et al. 2019

Birth Defects Research

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Background There is considerable variability in the prevalence of birth defects among racial/ethnic groups. This study estimated birth defect prevalence among the less studied non‐Hispanic (NH) Asian/Pacific Islander (PI) and American Indian/Alaska Native (AI/AN) populations in Texas relative to NH Whites. Methods Data were obtained from the Texas Birth Defect Registry from 1999 to 2015 for deliveries to Texas‐resident women who were NH White, NH Asian/PI, or AI/AN. This covers a live birth population of 2.6 million. Prevalence ratios and 95% confidence intervals (95% CIs) were calculated for NH Asian/PIs and AI/ANs (relative to NH Whites) for 44 birth defects using Poisson regression adjusting for maternal age. Results After adjustment there were 33 statistically significant prevalence ratios (aPRs). Among NH Asian/PIs, 23 defects had a lower aPR (0.38–0.86) and three defects had a higher aPR (1.19–2.50). AI/ANs had one defect with a significantly lower aPR (0.64) and six with a higher aPR (1.36–4.63). Conclusions Non‐Hispanic Asian/PIs generally have a lower prevalence ratio for many birth defects while AI/ANs have a higher prevalence ratio compared to NH Whites. These findings update the limited literature on this topic and warrant additional research to identify the true associations across a range of birth defects among these understudied racial/ethnic groups.

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Section: Discussionmentioning

confidence: 99%

The prevalence of birth defects among non‐Hispanic Asian/Pacific Islanders and American Indians/Alaska Natives in Texas, 1999–2015

Shumate

Hoyt

et al. 2019

Birth Defects Research

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“…Nativity status is a determinant of health and health disparities. 25 , 26 We found that adjusting for nativity status attenuated the association between socially assigned race and ever breastfed, alcohol consumption, smoking, gestational diabetes, depression before pregnancy, SGA, and LGA. These findings may suggest that nativity status plays a role in how individuals interpret interactions with the outside world.…”

Section: Discussionmentioning

confidence: 71%

Socially Assigned Race and the Health of Racialized Women and Their Infants

et al. 2022

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Introduction: While historically most public health research has relied upon self-identified race as a proxy for experiencing racism, a growing literature recognizes that socially assigned race may more closely align with racialized lived experiences that influence health outcomes. We aim to understand how women's health behaviors, health outcomes, and infant health outcomes differ for women socially assigned as nonwhite when compared with women socially assigned as white in Massachusetts. Methods: Using data from the Massachusetts Pregnancy Risk Assessment Monitoring System (PRAMS) Reactions to Race module, we documented the associations between socially assigned race (white vs. nonwhite) and women's health behaviors (e.g., initiation of prenatal care, breastfeeding), women's health outcomes (e.g., gestational diabetes, depression before pregnancy), and infant health outcomes (e.g., preterm birth, low birth weight [LBW]). Multivariable models adjusted for age, marital status, education level, nativity, receipt of Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) assistance during pregnancy, infant sex, plurality, and gestational age. Additional models adjusted for treatment by race, how often one thinks about race, and nativity. Results: Women socially assigned as nonwhite had higher odds of breastfeeding (adjusted odds ratio [AOR]: 1.86, 95% confidence interval [CI]: 1.54 to 2.25), lower odds of consuming alcohol (AOR: 0.27, 95% CI: 0.24 to 0.31), and lower odds of smoking (AOR: 0.30, 95% CI: 0.24 to 0.38) compared with those socially assigned as white. However, women socially assigned as nonwhite had higher odds of reporting gestational diabetes (AOR: 1.97, 95% CI: 1.49 to 2.61). Mothers socially assigned as nonwhite also had higher odds of giving birth to an LBW (AOR: 1.66, 95% CI: 1.29 to 2.14) and small-for-gestational age (AOR: 1.46, 95% CI: 1.19 to 1.80) infant compared with women socially assigned as white. Discussion: In comparison with women socially assigned as white, we observed poorer health outcomes for women who were socially assigned nonwhite despite engaging in more beneficial pregnancy-related health behaviors. Socially assigned race can provide an important context for women's experiences that can influence their health and the health of their infants.

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“…For example, infants of white mothers had the highest adjusted prevalence of nonsyndromic CL ± P and CP, and infants of Black mothers had the lowest prevalence, which is consistent with the previous studies. 7,16,18,20,21,25,27,[42][43][44][45] When stratifying by the presence/absence of additional defects, however, differences by race and ethnicity tended to be attenuated-in the case of CP -or eliminated-in the case of CL ± P-when additional defects were present. These epidemiologic differences further support the notion that isolated and nonisolated clefts may have some degree of distinct etiologies.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Nonsyndromic, Orofacial Clefts in Texas: Differences by Cleft Type and Presence of Additional Defects

Sanchez

Swartz

Langlois

et al. 2022

The Cleft Palate Craniofacial Journal

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To describe the current epidemiology of nonsyndromic cleft palate alone (CP) and cleft lip with or without cleft palate (CL ± P) in Texas and examine differences in the characteristics of infants with CP and CL ± P based on the presence/absence of additional defects. We used data from the Texas Birth Defects Registry, a statewide active birth defect surveillance system, from 1815 cases with CP and 5066 with CL ± P, without a syndrome diagnosis (1999-2014 deliveries). All live births in Texas were used for comparison. Poisson regression was used to calculate crude and adjusted prevalence ratios (aPR) for each characteristic, separately for each cleft subphenotype. The prevalence of CL ± P and CP in our study was estimated as 8.3 and 3.0 per 10 000 live births, respectively. After adjusting for several characteristics, several factors were associated with CL ± P, CP, or both, including infant sex and maternal race/ethnicity, age, smoking, and diabetes. There were several differences between infants with isolated versus nonisolated clefts. For example, maternal prepregnancy diabetes was associated with an increased prevalence of CL ± P (aPR 7.91, 95% confidence interval [CI]: 5.53, 11.30) and CP (aPR 3.24, 95% CI: 1.43, 7.36), but only when additional defects were present. Findings from this study provide a contemporary description of the distribution of orofacial clefts in Texas accounting for differences between isolated and nonisolated clefts. They may contribute to increasing our understanding of the etiology of CP and CL ± P.

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Prevalence of selected birth defects by maternal nativity status, United States, 1999–2007

Cited by 15 publications

References 38 publications

The prevalence of birth defects among non‐Hispanic Asian/Pacific Islanders and American Indians/Alaska Natives in Texas, 1999–2015

The prevalence of birth defects among non‐Hispanic Asian/Pacific Islanders and American Indians/Alaska Natives in Texas, 1999–2015

Socially Assigned Race and the Health of Racialized Women and Their Infants

Epidemiology of Nonsyndromic, Orofacial Clefts in Texas: Differences by Cleft Type and Presence of Additional Defects

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