Prevalence of Severe Acute Respiratory Syndrome Coronavirus-2 among the Young People and Association Between Diabetes, Hypertension, and Severe Acute Respiratory Syndrome Coronavirus-2

Akter, Aklima; Tabassum, Nafisa; Rahman, Arifur

doi:10.4103/bbrj.bbrj_220_20

Cited by 4 publications

(1 citation statement)

References 20 publications

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“…Our previous study was conducted in the same place within 752 NP and OP specimens were taken in this study period from suspected patients, among which 218 (28.5%) was positive and 528 (71.5%) was negative. Among the 218 positive 158 (78.8%) male and 56 (26.2%) female [16]. Another study was conducted in Brahmanbaria medical college 2021 our samples were 2025, about 1145 (56.54%) cases were found positive.…”

Section: Discussionmentioning

confidence: 86%

Estimation of COVID-19 Prevalence in a Tertiary Care Hospital in Bangladesh & Impact of COVID-19 Vaccine

Akter¹,

Rahman²,

Rahman³

et al. 2022

EJCBS

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Section: Discussionmentioning

confidence: 86%

Estimation of COVID-19 Prevalence in a Tertiary Care Hospital in Bangladesh & Impact of COVID-19 Vaccine

Akter¹,

Rahman²,

Rahman³

et al. 2022

EJCBS

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Omicron, a New Variant of Severe Acute Respiratory Syndrome Coronavirus-2 Virus

Kumar

2022

Biomedical and Biotechnology Research Journal (BBRJ)

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Background: Currently, a massive surge of Omicron (a new variant of severe acute respiratory syndrome coronavirus-2 [SARS-CoV-2]) is experiencing in several continents of the world (Asia, Europe, USA, etc.). Omicron (B.1.1.529) is the third variant of concern (VOC) that has emerged now in the COVID-19 pandemic after the Alpha (B.1.1.7) VOC (first reported in the UK in December 2020, followed by Delta (B.1.617.2) in mid-2021 in India). Omicron variant was emerged in South Africa and has now found in several countries. Methods: The spread of variants cannot be stopped because countries of the world are connected. This new variant can evade COVID-19 vaccine response and is highly transmissible because Omicron is differing from other variants in many aspects. Omicron has more mutations as compared to Alpha and Delta variants of SARS-CoV-2. Results: It was detected early on a global scale relative to other variants. The more opportunities viruses have to spread, the more it will replicate, the more opportunities virus has to undergo mutations, and create new variants. Omicron may not be horrible and serious as compared to Delta, but its early detection could prevent people. Omicron is an upper respiratory infection, whereas Delta resides in lower respiratory tract. Spread of Omicron is fast, but nothing can say about its severity because there is not much information available on Omicron. Conclusions: Currently, scientists and epidemiologists are working tirelessly together to find out what Omicron can do. This article explains genome structure of SARS-CoV-2, its pathogenesis, global upsurge, devastation, and future prospect.

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Correlation of Single-Nucleotide Polymorphism at Interferon-Gamma R1 (at Position − 56) in Positive Purified Protein Derivative Health Workers with COVID-19 Infection

Besharati

Varahram

Farnia

et al. 2022

The International Journal of Mycobacteriology

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Background: The aim of the present study was to investigate the susceptibility of purified protein derivative (PPD) plus health-care workers to SARS-CoV-2 (COVID-19). For this reason, single-nucleotide polymorphism (SNP) of interferon-gamma (IFN-γ) gene at position +2109 and IFN-γ receptor 1 (R1) at position −56 was assessed in PPD plus group before and after COVID-19 infection (2017–2018; 2020–2021). Methods: The selected study cases (n = 100) that were working in tuberculosis (TB) unite (5–10 years) with PPD positivity >15 mm (16–20 mm) were included in this investigation. Sampling was done twice, once before and after the COVID-19 pandemic. Group A contains 50 samples collected from the GenBank TB laboratory that belong to TB staff before the pandemic (2017–2018). The other sample (Group B; 2021) was collected from the same unite during the COVID-19 pandemic. The SNP in the IFN-γ gene (+2109; 670 bp) and IFN-γ R 1 (−56; 366 bp) was performed using a specific primer and the polymerase chain reaction products were digested using restriction enzyme Fau I and Bts I, respectively. Statistical analyses were used to obtain the frequency of alleles among all studied cases. The confidence intervals (CIs) and t-test were calculated using the SPSS and GraphPad Prism software. Results: In overall, the most frequent genotype in Group A was AA (41/50; 82%) and Group B was 76% (38/50) in position + 2109 (odds ratio [OR] = 0.69, 95% CI, 0.26–1.83, and P = 0.46). Although in position −56, the most frequent genotype in Group A was TT (35/50; 70%) which significantly was than Group B TT (15/50; 30%) (OR = 0.184, 95% CI, 0.78–0.43, and P = 0.00). The frequency of allele A was more in both groups at position + 2109 (OR = 0.815, 95% CI, 0.23–2.86, and P = 0.75), whereas the dominate allele at position −56 was T in Group A (OR = 1.37, 95% CI, 0.62–3.02, and P = 0.42). Conclusion: No significant differences were observed in + 2109 in genotype among Group A and B. The main differences were seen in IFN-γ R1 at position (−56) between Group A and B. Hence, the IFN-γ R1 may play important role in COVID-19 infection. However, more study is needed to clear the IFN-γ correlation to COVID-19 infection.

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Prevalence of Severe Acute Respiratory Syndrome Coronavirus-2 among the Young People and Association Between Diabetes, Hypertension, and Severe Acute Respiratory Syndrome Coronavirus-2

Cited by 4 publications

References 20 publications

Estimation of COVID-19 Prevalence in a Tertiary Care Hospital in Bangladesh & Impact of COVID-19 Vaccine

Estimation of COVID-19 Prevalence in a Tertiary Care Hospital in Bangladesh & Impact of COVID-19 Vaccine

Omicron, a New Variant of Severe Acute Respiratory Syndrome Coronavirus-2 Virus

Correlation of Single-Nucleotide Polymorphism at Interferon-Gamma R1 (at Position − 56) in Positive Purified Protein Derivative Health Workers with COVID-19 Infection

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