Prevalence of Sickle Cell Disease in Pregnant Women and Neonates in Africa

Superimposed Hepatitis C Virus in Sickle Cell Disease Pregnant Woman

“…In high prevalence area, there are some predictive markers of poor pregnancy outcome such as late antenatal booking, anemia, and poor education that prompt recognition and careful management reduce associated morbidity and mortality. [910]…”

Sickle cell disease and maternal mortality in Nigeria

“…Importantly, this is not only in Nigeria. In a recent review of sickle cell and maternal mortality in Africa, Yadufashije et al, 1 also submitted that sickle cell disease is a silent killer which had been ignored in most African countries. They concluded that in almost every African country, there was very high risk of maternal fetal complications including deaths and premature deliveries.…”

“…Sickle cell is a genetic disease of the hemoglobin chain of the red blood cells. 1 This genetic disorder is usually inherited from one's parents. 2 As noted by World Health Organization, 3 sickle cell anaemia is a common genetic condition due to a haemoglobin disorderinheritance of mutant haemoglobin genes from both parents.…”

“…5 Sickle cell disease is a common genetic blood disorder that afflict mainly Africans, Brazilians, the Caribbean and Asians. 6 In Africa, 1 described it as a silent killer and one of the supreme public health issues of this era. Nigeria bears a heavy burden of the disease with 20 to 30 percent prevalence.…”