Prevalence of Sickle Cell Disease Among Anaemic Children Attending Mbeya Referral Hospital in Southern Tanzania

Musyoka, Augustine; Zebedayo, Kavavila; Mmbaga, Blandina T.

doi:10.24248/eahrj.v2i2.588

Cited by 3 publications

(3 citation statements)

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“…On the contrary, a study by [8], indicated that it is highly distributed among high-income countries. The findings also showed a high frequency among the biogas 12 (40%) and others 13 (43.33%) whereas studies by [14] showed wide destruction among the African and American Negroes The majority of the respondents 187 (60%) only attained primary education while a study by [7] showed a significant correlation between total knowledge score and educational level and occupation. Other findings showed that the disease was more in married mothers .in contrary, a study by [15], showed that there was no significant association between the disease and marital status.…”

Section: Knowledge Of Respondents About Home-based Care Of Scamentioning

confidence: 85%

“…Mostly in low-and middle-income countries with the majority of these birth in Africa, Nigeria has the highest population of people with sickle cell disease with about 150,000 children born with the disease yearly. [6] It was a haematological disorder present in most countries of sub-Saharan Africa in Tanzania between 50% to 75% of the children born with SCD die before reaching 5 years [7]. It is estimated that SCD affects approximately 100,000 Americans.…”

Section: Introductionmentioning

confidence: 99%

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Knowledge and Practices of Caregivers Towards Home-Based Care of Sickle Cell Anaemia Among Children Below Ten Years of Age Attending Jinja Regional Referral Hospital, Jinja City

Geoffrey

2023

IDOSR JAS

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Sickle cell disorders can be managed cost-effectively by programs that integrate treatment with early carrier detection through screening and genetic counselling. However, sickle cell disease is not well known or recognized by many individuals as a significant health problem with major complications, thus a large number of Ugandans are carriers of the trait but they are unaware of their status. Therefore, this study sought to determine the knowledge and practices of mothers towards the home-based care of sickle cell anaemia among children below 10 years at Jinja regional referral hospital in Jinja City. Simple random sampling was used to select the required number of participants, n equals 30. The questionnaire used consist of closed and open-ended questions to collect both qualitative and quantitative data. The data was analysed using descriptive statistics and presented in tables and figures. The study findings revealed that 59.3% of respondents had poor knowledge while 40.7% of respondents had good knowledge concerning home-based care of their children with SCA. 52.9% of the respondents had good practices while 47.1% had poor practices about homebased care of their children with SCA. So, it was concluded that caregivers lack adequate knowledge about home-based care of children with SCA with average good practices. Therefore, there is a need for government to come up with programs aimed at teaching mothers and the communities at large to impact knowledge on how to manage SCA. Health education should be done regularly and expanded to couples intending to marry and also screened during antenatal visits. There is also a need for more sensitization of the general public both by the government and professionally experienced health workers pertaining SCD in Uganda. Keywords: Sickle cell anaemia, Genetic counselling, Significant health problem, Children below 10 years, Mothers, Health workers.

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Section: Knowledge Of Respondents About Home-based Care Of Scamentioning

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Knowledge and Practices of Caregivers Towards Home-Based Care of Sickle Cell Anaemia Among Children Below Ten Years of Age Attending Jinja Regional Referral Hospital, Jinja City

Geoffrey

2023

IDOSR JAS

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“…Additionally, a study conducted in Zanzibar revealed that anemia was prevalent with mild anemia accounting for 43.8% of cases, moderate anemia for 22.9% and severe anemia for 2.4% (19).These frightening high anemic prevalence rate need immediate action from multifaceted dimensions.…”

Section: IIImentioning

confidence: 99%

The Prevalence, Etiology, And Outcome Of Anemia In Children Under Five On Admission In Three Hospitals Of Dar-Es-Salaam

Msinde

2023

Preprint

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Introduction: Childhood anemia remains a persistent global challenge, emerging as the most prevalent blood disorder among children worldwide. Its enduring prevalence underscores its significance as a hematological concern of substantial public health importance, owing to its wide prevalence and potential severity. Anemia's impact is particularly pronounced among children and expectant mothers. On a global scale, the World Health Organization (WHO) has taken significant measures to address this issue. These include implementing strategies such as iron supplementation, fortifying food sources with essential nutrients, promoting dietary diversity, and preventing conditions that contribute to anemia's occurrence. These collective efforts aim to alleviate the burden of anemia and enhance the health and well-being of vulnerable populations. Objectives: The objective of this study was to investigate the prevalence, etiologie, and clinical outcomes of anemia among children under five years of age upon admission in three district hospitals within the Dar-es-Salaam region. Methodology: The study employed an observational cross-sectional design to examine the prevalence, etiologies, and outcomes of anemia in children under five who were admitted to three district hospitals in Dar-es-Salaam. Data collection took place between November 2022 and July 2023, involving children manifesting clinical signs of anemia and their caregivers. A sample size of 327 was used. Structured questionnaires were administered, and data were analyzed using SPSS software, with descriptive statistics, chi-squared tests, Fisher's exact tests, and logistic regression employed to find associations. Ethical considerations were adhered to throughout the study. Results: The study analyzed data from 327 children under five years old admitted to three district hospitals in Dar-es-Salaam to determine the prevalence, etiologies, and outcomes of anemia. The overall prevalence of anemia was found to be 45.9%, with 21.38% having mild anemia, 60% moderate anemia, and 18.62% severe anemia. Factors associated with anemia included age, referral status, family size, age of caregivers, chronic illness, deworming status, iron supplementation, active bleeding, breastfeeding, feeding adequacy, and associated comorbidities. Anemic children showed longer stays in both the ICU and wards, with an increased need for mechanical ventilators and blood transfusions. Conclusion and recommendation: In conclusion, this study pinpoint the persistent burden of childhood anemia in the Dar-es-Salaam region, highlighting the need for comprehensive strategies to address its prevalence and impact. The high prevalence of anemia, particularly moderate and severe cases, suggests an important need for targeted interventions. To mitigate this issue, it is recommended that health authorities and stakeholders implement and reinforce iron supplementation programs, promote dietary diversity, enhance deworming efforts, and raise awareness about anemia's implications. Furthermore, healthcare facilities should prioritize early detection and management of anemia in pediatric patients to reduce the associated morbidity and resource utilization.

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Demographic Characteristics and Abo Blood Group Genotypes Distribution Among Sickle Cell Anemia Patients in Birnin Kebbi, Northwestern Nigeria

Tajudeen Olanrewaju Yahaya,

Asiya Koko Attahiru,

Abdulgafar Bala Ibrahim

et al. 2024

MBIOMJ

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Highlights Sickle cell anemia affects both males and females in Birnin Kebbi and is predominant among children between 1 to 10 years of age. It is also more prevalent but less severe among individuals with O- and A+ ABO blood groups in the city. Abstract Background: Demographic information and ABO blood group genotypes have been shown by studies to be useful tools in the management of sickle cell anemia. Regrettably, there is a dearth of literature on this information in Birnin Kebbi, northwestern Nigeria. Objective: This study determined demographic characteristics, ABO blood group genotypes, and sickle cell genotypes of sickle cell anemia patients in Birnin Kebbi. Material and Method: A structured checklist was used to collect data from the medical records of 99 patients who attended the Federal Medical Center in the city between November 2022 to November 2023. Result: The results revealed that most of the patients fell within the 1 to 10 years age group, comprising 44 individuals (44.4%), and the 11 to 20 years age group, comprising 33 individuals (33.3%). Of the patients, 48 (48.5%) were males, while 51 (51.5%) were females. Patients with ABO blood genotype O- (33.3%) and A+ (18.0%) were the most prevalent and least severely affected, while blood groups O+ (3%) and AB- (6%) were the least prevalent and most severely affected. Two variants of sickle cells (HbSS and HbSC) were identified, with HbSS (92.9%) being the most prevalent. Conclusion: Based on these findings, efforts should be made to ensure an ample blood supply with groups O-, A, and AB+ in blood banks. Moreover, studies have shown ABO blood groups to influence responses to diets, so precision medicine tailored to individual patients' blood groups is recommended. Individuals with O+ and AB- -blood groups should be given special attention, as they exhibit the severe form of the disease.

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Prevalence of Sickle Cell Disease Among Anaemic Children Attending Mbeya Referral Hospital in Southern Tanzania

Cited by 3 publications

References 20 publications

Knowledge and Practices of Caregivers Towards Home-Based Care of Sickle Cell Anaemia Among Children Below Ten Years of Age Attending Jinja Regional Referral Hospital, Jinja City

Knowledge and Practices of Caregivers Towards Home-Based Care of Sickle Cell Anaemia Among Children Below Ten Years of Age Attending Jinja Regional Referral Hospital, Jinja City

The Prevalence, Etiology, And Outcome Of Anemia In Children Under Five On Admission In Three Hospitals Of Dar-Es-Salaam

Demographic Characteristics and Abo Blood Group Genotypes Distribution Among Sickle Cell Anemia Patients in Birnin Kebbi, Northwestern Nigeria

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