Prevalence of Substance Use Among the General Population: Situation in Croatia and Comparison with Other European Countries

Tkalić, Renata Glavak; Miletić, Geran-Marko; Sakoman, Slavko

doi:10.5559/di.22.4.01

Cited by 7 publications

(5 citation statements)

References 1 publication

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“…Our results showing that healthy subjects actively smoked more than asthma patients are not unexpected since many asthma patients (30.83% in our study) quit smoking because of more severe asthma symptoms, in addition to the benefit of smoking cessation in improving lung function [ 49 ]. The observed 34.17% of smokers in the control group is consistent with the smoking frequency (37.45%) in the general population of Croatia [ 50 ]. On the other hand, the 8.33% of active smokers in the asthma group are in line with the reports of smoking among asthma patients in Brazil and Spain, but much lower than what is seen in many other countries [ 51 ].…”

Section: Discussionsupporting

confidence: 81%

Plasma Brain-Derived Neurotrophic Factor (BDNF) Concentration and BDNF/TrkB Gene Polymorphisms in Croatian Adults with Asthma

Sreter¹,

Popović‐Grle

Lampalo

et al. 2020

JPM

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Brain-derived neurotrophic factor (BDNF) and its tropomyosin-related kinase B (TrkB) receptor might contribute to normal lung functioning and immune responses; however, their role in asthma remains unclear. Plasma BDNF concentration, as well as BDNF and NTRK2 (TrkB gene) polymorphisms, were investigated in 120 asthma patients and 120 healthy individuals using enzyme-linked immunosorbent assay and polymerase chain reaction, respectively. The genotype and allele frequencies of BDNF Val66Met (rs6265) and NTRK2 rs1439050 polymorphisms did not differ between healthy individuals and asthma patients, nor between patients grouped according to severity or different asthma phenotypes. Although plasma BDNF concentrations were higher among healthy subjects carrying the BDNF Val66Met GG genotype compared to the A allele carriers, such differences were not detected in asthma patients, suggesting the influences of other factors. Plasma BDNF concentration was not affected by NTRK2 rs1439050 polymorphism. Asthma patients had higher plasma BDNF concentrations than control subjects; however, no differences were found between patients subdivided according to asthma severity, or Type-2, allergic, and eosinophilic asthma. Higher plasma BDNF levels were observed in asthma patients with aspirin sensitivity and aspirin-exacerbated respiratory disease. These results suggest that plasma BDNF may serve as a potential peripheral biomarker for asthma, particularly asthma with aspirin sensitivity.

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Section: Discussionsupporting

confidence: 81%

Plasma Brain-Derived Neurotrophic Factor (BDNF) Concentration and BDNF/TrkB Gene Polymorphisms in Croatian Adults with Asthma

Sreter¹,

Popović‐Grle

Lampalo

et al. 2020

JPM

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“…Furthermore, the drug consumption trends which were determined in the present study were only partialy in agreement with the results of general population surveys performed in Croatia in 2011 and 2015, which indicated a significant increase only in the consumption of cannabis (2.9% last-month prevalence in 2011; 5.0% last-month prevalence in 2016) (Glavak Tkalic et al, 2013;Glavak Tkalic et al, 2016), whereas the differences in the consumption prevalence of other illicit drugs were not found to be significant. Our study suggests that the outcome of national population surveys on drug consumption is not necessarily representative for larger cities.…”

Section: Multiannual Trends In Drug Consumption Patterns and Comparissupporting

confidence: 88%

“…The selection of target compounds was made based on the available data on drug consumption patterns in Croatia (Glavak Tkalic et al, 2013) and in the city of Zagreb Terzic et al, 2010). Selected analytes included morphine (MOR), morphine-3-glucuronide M3Gand 6-acetylmorphine (6-AM) as principal heroin-derived substances as well as benzoylecgonine (BE), amphetamine (AMP), methamphetamine (MAMP), 3,4-methylendioximethamphetamine (MDMA), 11-nor-9-carboxy-tetrahydrocannabinol (THC-COOH) and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) as principal biomarkers of cocaine, amphetamine, methamphetamine, MDMA, cannabis and methadone consumption, respectively.…”

Section: Selection Of Target Compoundsmentioning

confidence: 99%

Long-term monitoring of drug consumption patterns in a large-sized European city using wastewater-based epidemiology: Comparison of two sampling schemes for the assessment of multiannual trends

Krizman-Matasic

Senta

Kostanjevečki

et al. 2019

Science of The Total Environment

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A comprehensive study aimed at monitoring of temporal variability of illicit drugs (heroin, cocaine, amphetamine, MDMA, methamphetamine and cannabis) and therapeutic opiate methadone in a large-sized European city using wastewater-based epidemiology (WBE) was conducted in the city of Zagreb, Croatia, during an 8-year period (2009-2016). The study addressed the impact of different sampling schemes on the assessment of temporal drug consumption patterns, in particular multiannual consumption trends and documented the possible errors associated with the one-week sampling scheme. The highest drug consumption prevalence was determined for cannabis (from 59 ± 18 to 156 ± 37 doses/day/1000 inhabitants 15-64 years), followed by heroin (from 11 ± 10 to 71 ± 19 doses/day/1000 inhabitants 15-64 years), cocaine (from 8.3 ± 0.9 to 23 ± 4.0 doses/day/1000 inhabitants 15-64 years) and amphetamine (from 1.3 ± 0.9 to 21 ± 6.1 doses/day/1000 inhabitants 15-64 years) whereas the consumption of MDMA was comparatively lower (from 0.18 ± 0.08 to 2.7 doses ±0.7 doses/day/1000 inhabitants 15-64 years). The drug consumption patterns were characterized by clearly enhanced weekend and Christmas season consumption of stimulating drugs (cocaine, MDMA and amphetamine) and somewhat lower summer consumption of almost all drugs. Pronounced multiannual consumption trends were determined for most of the illicit drugs. The investigated 8-year period was characterized by a marked increase of the consumption of pure cocaine (1.6-fold), THC (2.7-fold), amphetamine (16-fold) and MDMA (15-fold) and a concomitant decrease (2.3-fold) of the consumption of pure heroin. The heroin consumption decrease was associated with an increase of methadone consumption (1.4-fold), which can be linked to its use in the heroin substitution therapy. The estimated number of average methadone doses consumed in the city of Zagreb was in a good agreement with the prescription data on treated opioid addicts in Croatia.

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“…More frequent alcohol consumption and more frequent intoxication established in boys in relation to girls is in line with Croatian and European research (Bouillet and Čale-Mratovic, 2007;Glavak Tkalić, Miletić and Sakoman, 2013;Haug, Schaub, Salis Gross, John and Meyer, 2006;Kalebić Maglica and Martinac Dolčić, 2015;Kuzman and Katalinić, 2005;Ljubotina and Galić;Nolen-Hoeksema, 2004;Sakoman, Kuzman, and Raboteg-Šarić, 1999;Piko, 2006;Windle, 2003). According to Croatian research data on the general population, men drink and get drunk more often than women (Štimac Grbić and Glavak Tkalić, 2020).…”

Section: Alcohol Consumption Habits Among Adolescents In the Split-dalmatia County And Comparison With Regard To Socio-demographic Characsupporting

confidence: 85%

“…Higher-grade students consume alcohol significantly more than lower-grade students in all three measured variables (life, one year, one month), with significant differences between Results of the two separate regression analyses (Table 7) show that the envisaged set of predictors (gender, age, perceived parental monitoring, perceived potential parental reactions) statistically significantly predict alcohol consumption in life (F(7.1241)=91.449; p<0.000) and in the last 30 days (F(7.1241)=50.813; p<0.000). The set of predictors predicts 33.7% variability of alcohol consumption in life, and Utvrđena učestalija konzumacija alkohola i učestalija opijenost kod mladića u odnosnu na djevojke u skladu je s domaćim i europskim istraživanjima (Bouillet i Čale-Mratović, 2007;Glavak Tkalić, Miletić i Sakoman, 2013;Haug, Schaub, Salis Gross, John i Meyer, 2013;Kalebić Maglica i Martinac Dorčić, 2015;Kuzman i Katalinić, 2005;Ljubotina i Galić, 2002;Nolen-Hoeksema, 2004;Sakoman, Kuzman, i Raboteg-Šarić, 1999;Piko, 2006;Windle, 2003). Prema hrvatskim podatcima istraživanja na općoj populaciji muškarci piju i opijaju se češće nego žene (Štimac Grbić i Glavak Tkalić, 2020).…”

Section: Description Of and Differences In Drinking Habits Among Adolescents' In The Split-dalmatia County With Regard To Socio-demographmentioning

confidence: 99%

Odnos navika konzumacije alkohola i percepcije roditeljskih ponašanja kod adolescenata Splitsko-dalmatinske županije

Matković

Petak²,

Ključević

2021

Kriminol. soc. integr. (Online)

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Konzumacija alkohola adolescenata rizična je zbog niza kratkoročnih i dugoročnih posljedica. Neprijeporan je utjecaj obitelji na početak konzumacije te na učestalo i prekomjerno pijenje, što je objašnjeno nizom rizičnih i zaštitnih čimbenika obiteljskog okruženja. Njihovo poznavanje i prepoznavanje pomaže u osmišljavanju učinkovitih preventivnih programa radi smanjivanja prevalencije konzumacije alkohola djece i mladih. U školskoj godini 2019./2020. provedeno je istraživanje na stratificiranom uzorku. Sudjelovalo je 1409 učenika (48,3% mladića i 51,7% djevojaka) u dobi od 13 do 19 godina (M = 15,84; sd = 1,46) iz 16 osnovnih (osmi razred) i 20 srednjih škola (sva četiri razreda) s područja Splitsko-dalmatinske županije. Cilj je rada utvrditi odnos konzumacije alkohola među adolescentima s njihovom percepcijom roditeljskog nadzora, očekivanih roditeljskih reakcija na opijanje te zadovoljstvom odnosa s roditeljima, ali i ponuditi uvid u trenutačne navike konzumacije alkohola među adolescentima Splitsko-dalmatinske županije. Utvrđene su razlike u navikama konzumacije alkohola s obzirom na rod i razred. U usporedbi s učenicima koji manje piju, učenici skloniji konzumaciji alkohola rjeđe smatraju da postoje pravila ponašanja izvan kuće, da njihovi roditelji znaju gdje su i s kim se druže te misle da bi reakcije njihovih roditelja na opijanje bile blaže. Konzumacija alkohola nije se pokazala povezanom sa zadovoljstvom odnosa s roditeljima. Rod, dob, percepcija nadzora i očekivane roditeljske reakcije na opijanje predviđaju 33,7% varijabiliteta konzumacije alkohola u životu i 22,3% varijabiliteta konzumacije u posljednjih mjesec dana. Dob, rod, percepcija roditeljskog nadzora, očekivane reakcije roditelja na opijanje i učestalost konzumacije alkohola u posljednjih mjesec dana predviđaju zajedno 40,3% varijabiliteta učestalosti opijanja u životu i 24,3% varijabiliteta učestalosti opijanja u posljednjih mjesec dana.

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Prevalence of Substance Use Among the General Population: Situation in Croatia and Comparison with Other European Countries

Cited by 7 publications

References 1 publication

Plasma Brain-Derived Neurotrophic Factor (BDNF) Concentration and BDNF/TrkB Gene Polymorphisms in Croatian Adults with Asthma

Plasma Brain-Derived Neurotrophic Factor (BDNF) Concentration and BDNF/TrkB Gene Polymorphisms in Croatian Adults with Asthma

Long-term monitoring of drug consumption patterns in a large-sized European city using wastewater-based epidemiology: Comparison of two sampling schemes for the assessment of multiannual trends

Odnos navika konzumacije alkohola i percepcije roditeljskih ponašanja kod adolescenata Splitsko-dalmatinske županije

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