Prevalence of suicide attempts in individuals with schizophrenia: a meta-analysis of observational studies

Lu, Li; Dong, Min; Zhang, Ling; Zhu, Xiao; Ungvári, Gábor S.; Ng, Chee H.; Wang, Gang; Xiang, Yu Tao

doi:10.1017/s2045796019000313

Cited by 65 publications

(45 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various studies on different factors associated with suicide in schizophrenia patients, such as age, gender, age of onset of illness and duration of illness yielded conflicting results. 7,8,36,[45][46][47] Our findings found no association between age, gender, marital status, age of onset of illness and duration of illness with suicidality in schizophrenia inpatients, which has been reported in previous studies. 26,38 Earlier studies showed that suicidal risk in schizophrenia patients peaked during the first week of hospitalization and during the first week after discharge.…”

supporting

confidence: 50%

<p>Prevalence and Factors Associated with Suicidal Ideation in Institutionalized Patients with Schizophrenia</p>

Chong¹,

Wahab²,

Muthukrishnan³

et al. 2020

PRBM

View full text Add to dashboard Cite

Purpose The shorter life expectancy and increased risk of suicide in patients with schizophrenia have been well documented. However, study outcomes on suicidality in this special population have been few to date. This study investigated the prevalence and factors associated with suicidal ideation in a population of institutionalized patients with schizophrenia. Methods Two hundred fifty-six patients with schizophrenia between the age of 18 and 65 years were randomly recruited. This cross-sectional study utilised the Calgary Depression Scale for Schizophrenia (CDSS), the Positive and Negative Syndrome Scale (PANSS) and the Psychotic Symptom Rating Scale (PSYRATS-AH). Univariate analysis was performed using an independent t -test or chi-square test, followed by binary logistic regression to determine the factors associated with increased suicidal risks. Results The socio-demographic factors associated with suicidal ideation included level of education ( p =0.039); secondary-level education (OR=5.76, 95% CI:1.49, 22.34, p =0.011) and tertiary-level education (OR=9.30, 95% CI: 1.80, 48.12, p =0.008) posed a greater risk. A history of attempted suicide (OR=2.09, 95% CI: 1.01, 4.36, p =0.049) and the presence of co-morbid physical illnesses (OR=2.07, 95% CI: 1.02, 4.21, p =0.044) were also found to be associated with a suicidal ideation. Other significant factors associated with suicidal thoughts were concurrent depression (OR=9.68, 95% CI: 3.74, 25.05, p <0.001) and a higher PSYRATS score in emotional characteristics of auditory hallucinations (OR=1.13, 95% CI: 1.06, 1.21, p <0.001). Conclusion Suicide in schizophrenia appears to be more closely associated with certain socio-demographic factors and affective symptoms. Appropriate screening and treatment addressing these challenges must be emphasized if suicidal thoughts and actions are to be reduced.

show abstract

supporting

confidence: 50%

<p>Prevalence and Factors Associated with Suicidal Ideation in Institutionalized Patients with Schizophrenia</p>

Chong¹,

Wahab²,

Muthukrishnan³

et al. 2020

PRBM

View full text Add to dashboard Cite

show abstract

“…Moreover about one quarter of patients with bipolar disorder have a seasonal pattern of their depressive recurrences, and one out of six patients present with seasonal manic recurrences (32,33). Patients with schizophrenia are up to 20 times more likely to die by suicide than the general population use (34). A particular shared vulnerability between suicidal behaviors and psychiatric disorders has been con rmed in our study.…”

Section: Discussionsupporting

confidence: 73%

Seasonal Changes and Decrease of Suicides and Suicide Attempts in France Over the Last 10 Years”.

Akkaoui

Chan-Chee

Laaidi

et al. 2021

Preprint

View full text Add to dashboard Cite

Introduction: The objective of this study was to examine the evolution of suicides and suicide attempts over the last 10 years in France. Methods: We analyzed the number of deaths by suicide and suicide attempts in metropolitan France (2009-2018) from French national databases, on a daily, weekly or monthly basis. Seasonal variation in suicide rates was modeled using a cosinor function. Based on this model, we determined the association of suicides and suicide attempts with geographic characteristics, age, gender, means used and psychiatric disorders. Results: The number of suicides and suicide attempts decreased over the last ten years in France (mean decrease of 14.49% and 11.69% per year). We observed a significant and recurrent seasonal pattern of suicides and suicide attempts in France, with a peak in spring. The suicide and suicide attempt rates were higher in the northern departments of France. Suicides were more frequent for men (75%) and middle-age individuals (45-54 years old), while suicide attempts were more frequent for women (62%) and young adults and middle-age individual (15-19 and 40-49 years old). Nearly two-thirds of the patients who attempted suicide suffered from comorbid psychiatric disorders. Mood disorders was the most frequent comorbid psychiatric disorder (54%). Voluntary drug intoxication was the most common means of suicide attempt (80%), and hanging was the most common means of suicide (54%).Conclusion: The number of suicides and suicide attempts decreased in France over the last 10 years, with large and recurrent seasonal variations. These findings could be used to alert and adjust prevention policies, as well as developing preventive strategies such as chronotherapeutics.

show abstract

“…Diagnostic and Statistical Manual of Mental Disorders, third edition (DSM-III), DSM-IV, and the Tenth Revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10)); Intervention ( I ): not applicable; Comparison ( C ): not applicable; Outcome ( O ): prevalence of SI and/or SP or relevant data that enabled calculations of the prevalence of SI/SP; Study design ( S ): cross-sectional or cohort studies (only the baseline data of cohort studies were extracted). Exclusion criteria included: (1) timeframe of prevalence of SI and/or SP was missing; (2) studies published in non-English; (3) in order to increase homogeneity [ 17 ], studies with mixed samples (e.g. schizoaffective or schizophrenia spectrum disorders) in which data on schizophrenia cannot be extracted were excluded.…”

Section: Methodsmentioning

confidence: 99%

“…In order to develop and adopt effective measures and public education to reduce suicide risk and relevant negative health outcomes, exploring the epidemiology of suicidality in people living with schizophrenia is of great public health significance. A meta-analysis [ 17 ] showed the pooled lifetime prevalence of SA was 26.8% (95% CI: 22.1−31.9%) among people living with schizophrenia. In contrast, no meta-analysis was published for pooled SI, and the estimates within individual studies [ 18 – 23 ] ranging between 11.0% in China [ 23 ] and 51.4% in the USA [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Worldwide prevalence of suicidal ideation and suicide plan among people with schizophrenia: a meta-analysis and systematic review of epidemiological surveys

et al. 2021

Self Cite

View full text Add to dashboard Cite

Schizophrenia is a severe psychiatric disorder with high premature mortality rates. This is a meta-analysis and systematic review of the prevalence of suicidal ideation (SI) and suicide plan (SP) among people with schizophrenia. PubMed, Web of Science, Embase, and PsycINFO were systematically searched from their respective inception to October 10, 2020. Data on prevalence of SI and/or SP were synthesized using the random effects model. Twenty-six studies covering 5079 people with schizophrenia were included for meta-analysis. The lifetime and point prevalence of SI were 34.5% (95% CI: 28.2−40.9%), and 29.9% (95% CI: 24.2−35.6%), respectively. The lifetime prevalence of SP was 44.3% and the point prevalence of SP ranged between 6.4 and 13%. Subgroup and meta-regression analyses revealed that source of patients, survey countries, and sample size were significantly associated with the point prevalence of SI, while male proportion and quality assessment scores were significantly associated with the lifetime and point prevalence of SI. Survey time and mean age were significantly associated with lifetime prevalence of SI. Both SI and SP are common in people living with schizophrenia, especially in males and inpatients. Routine screening and effective interventions for SI and SP should be implemented in this population.

show abstract

Prevalence of suicide attempts in individuals with schizophrenia: a meta-analysis of observational studies

Cited by 65 publications

References 62 publications

<p>Prevalence and Factors Associated with Suicidal Ideation in Institutionalized Patients with Schizophrenia</p>

<p>Prevalence and Factors Associated with Suicidal Ideation in Institutionalized Patients with Schizophrenia</p>

Seasonal Changes and Decrease of Suicides and Suicide Attempts in France Over the Last 10 Years”.

Worldwide prevalence of suicidal ideation and suicide plan among people with schizophrenia: a meta-analysis and systematic review of epidemiological surveys

Contact Info

Product

Resources

About