Prevalence of symptoms among patients with advanced cancer: An international collaborative study

Vainio, Anneli; Auvinen, Anssi

doi:10.1016/0885-3924(96)00042-5

Cited by 423 publications

(308 citation statements)

References 28 publications

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“…This symptom has traditionally been believed to be a rare manifestation compared to solid tumor settings [1][2][3]. Nevertheless, more recent studies have shown a high prevalence of this symptom in the hematological population [4][5][6][7], in which the occurrence of specific pain syndromes has been described [8]. However, no study on this topic concerning patients with blood-related neoplasm in the home care (HC) setting has been reported.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology, features and outcome of pain in patients with advanced hematological malignancies followed in a home care program: an Italian survey

et al. 2007

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We report on epidemiology, features, outcome, and domiciliary management of pain in patients with advanced hematological malignancies followed by an experienced hospital-based home care (HC) team. Out of 469 patients, 244 (52%) experienced a total of 284 pain syndromes. Pain intensity was rated from mild to moderate in 31% and from moderate to severe in 69% of them. The diagnosed pain mechanisms were deep somatic in 56%, superficial somatic in 15%, visceral 14%, mixed 8%, and neuropathic in 7% of pain syndromes, respectively. Incident pain was observed in 38% of all pain syndromes. In every diagnostic group, deep somatic pain was prevalent. Moreover, 85% of visceral pain syndromes were observed in patients affected by non-Hodgkin's lymphoma (NHL). In addition, out of 284 pain syndromes, 150 (51%) were caused by bone involvement. The most frequent recognized pain provocative mechanisms were bone marrow expansions, osteolysis, lymph node enlargement, and mucositis. In our experience, an approach based on the association of causal therapies and analgesics allows optimal control of most pain syndromes. Therefore, pain is a major problem in patients affected by advanced hematological malignancies, and its management can be effective and feasible when carried out by a skilled HC team.

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Section: Introductionmentioning

confidence: 99%

Epidemiology, features and outcome of pain in patients with advanced hematological malignancies followed in a home care program: an Italian survey

et al. 2007

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“…Estimates suggest that up to 79% of hospitalized cancer patients experience pain [8][9][10][11]. The primary treatment for cancer-related pain focuses on the use of analgesic and adjuvant medications; and while complementary therapies may be offered in some settings, they are widely considered to be underutilized [9,[12][13].…”

Section: Introductionmentioning

confidence: 99%

Patients’ perceptions of the effectiveness of guided imagery and progressive muscle relaxation interventions used for cancer pain

Kwekkeboom

Hau

Wanta

et al. 2008

Complementary Therapies in Clinical Practice

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Relaxation and guided imagery are useful strategies for cancer pain; however, their effects vary from patient to patient. Patients' perceptions of these treatments and factors that contribute to their effectiveness have not previously been described. Data from interviews conducted after a trial of guided imagery and progressive muscle relaxation (PMR) interventions were analyzed to compare patients' perceptions of treatment effects with observed changes in pain scores, and to explore patients' ideas about factors that contributed to the effectiveness of each intervention. Post-study interviews were conducted with 26 hospitalized patients with cancer-pain who had completed trials of guided imagery and PMR. In most cases, participants' perceptions of treatment effects matched observed changes in pain scores. Participants described treatment and patient characteristics that influenced effectiveness of the interventions such as active involvement in the intervention, guided instructions, providing a source of distraction, stimulating relaxation, individual abilities and preferences, and pain qualities.

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“…1 Pain is reported by 60% to 70% of patients with advanced cancer 2,3 and increases as patients approach death. 4 Fortunately, in the vast majority of cases, adequate pain control can be achieved by using the World Health Organization guidelines.…”

Section: Introductionmentioning

confidence: 99%

“…Vainio and Auvinen assessed 1840 cancer patients in 7 hospices and reported significant intercenter variations in pain prevalence and intensity; the proportion of patients with severe pain ranged from 10% to 56%. 1 In a Taiwanese study of 480 cancer patients in 15 outpatient clinics, Hsieh reported major variations in satisfaction with pain control. 9 However, those previous studies did not appropriately consider case-mix or organizational context, which may affect pain management outcomes.…”

Section: Introductionmentioning

confidence: 99%

Variations in pain management outcomes among palliative care centers and the impact of organizational factors

Shin

Hwang

et al. 2012

Cancer

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BACKGROUND:The assessment of pain management outcomes is important for the quality assurance of palliative care. The objective of this study was to determine whether there are significant variations in pain management outcomes among palliative care centers and whether they are affected by organizational factors. METHODS: Data used in this investigation were from the 2009 Korean Terminal Cancer Patient Information System and administrative records of the 34 inpatient palliative care centers designated by the Korean Ministry of Health and Welfare in 2009. Self-reported pain scores (range, from 0 to 10) at admission and 1 week after admission were prospectively collected. Multilevel mixed-effect regression models were used to analyze the variations and the impact of organizational-level factors on 2 pain management outcomes (ie, reduction in average pain score and achievement of adequate pain control at 1 week after admission). RESULTS: In total, 1711 patients with terminal cancer were included in the analyses. The mean reduction in the pain score was 0.69 to 1.91 after 1 week, and most patients (82.8%) achieved adequate pain control. There were significant variations in pain management outcomes among palliative care centers. Higher composite scores for human resources adequacy were associated significantly with a greater reduction in pain score (b, 0.11; 95% confidence interval, 0.01-0.21), and achievement of adequate pain control (adjusted odds ratio, 1.26; 95% confidence interval, 1.10-1.45). CONCLUSIONS: There were significant variations in pain management outcomes among inpatient palliative care centers, and they were affected by organizational factors, such as human resources adequacy. Cancer 2012;118:5688-97.

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Prevalence of symptoms among patients with advanced cancer: An international collaborative study

Cited by 423 publications

References 28 publications

Epidemiology, features and outcome of pain in patients with advanced hematological malignancies followed in a home care program: an Italian survey

Epidemiology, features and outcome of pain in patients with advanced hematological malignancies followed in a home care program: an Italian survey

Patients’ perceptions of the effectiveness of guided imagery and progressive muscle relaxation interventions used for cancer pain

Variations in pain management outcomes among palliative care centers and the impact of organizational factors

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