OBJECTIVE:Co-morbidity is a medical condition accompanied to the primary condition for which patient is seeking medical or dental care. To determine the frequency of medical co-morbid conditions in dental patients. METHODOLOGY: After obtaining informed consent, a comprehensive predesigned history form was implemented to record patient's medical conditions. Different variables recorded for each participant were age, gender and history of medical co-morbid conditions including diabetes mellitus, hypertension, ischemic heart diseases, renal disorders, typhoid, thyroid disorder, degenerative joint disorder, asthma, hepatitis B, hepatitis C, hepatitis A and E, HIV and tuberculosis. RESULTS: In this study, hypertension accounted for 9.5% in total number of patients followed by degenerative joint disorders and hepatitis C with the same frequency of 5.2%. Diabetes mellitus and hepatitis B accounted for 3.4% of the patients CONCLUSION: This study concludes that presentation of medically compromised patients in dentistry is inevitable.