Prevalence of Thyroid Disorders and Reference Range of Thyroid Hormones among Pregnant Women in Bosaso City, Somalia

Abstract

Background: Thyroid dysfunctions are among the most prevalent of medical conditions, and considered the most prevalent disorders in women during pregnancy, and can adversely affect obstetric outcomes. The aim of this study was to determine the prevalence of thyroid disorders among pregnant women in Bosaso city, Somalia, and to initiate normal levels of thyroid related hormones
 Materials and methods: This study was cross-sectional hospital-based study conducted at University of Health Science Hospital (Prof Abdirisak Hospital), Bosaso city, Somalia during the period of August 2023 to December 2023. a total of 250 pregnant women were included in the study. A total of five ml of whole blood was collected from each participant into sterile plain containers for thyroid hormones estimation. Estimation of thyroid hormones was done by using CLIA technique (Maglumi 800). The data was gathered using per-designed structural questionnaire and the SPSS 26.0 statistical software (SPSS Inc., USA) was used for statistical analysis.
 Results: The overall prevalence of thyroid disorders were 33 (13.2%), 8% of them were hyperthyroidism and the rest 5.2% were hypothyroidism. The reference range for TSH, T3 and T4 were (0.07 mlU/L–4.14 mlU/L), (0.19 nmol/L–4.98 nmol/L), and (0.21 nmol/L–3.69 nmol/L) respectively.
 Conclusion: This study concluded that there is a slightly higher frequency of thyroid dysfunction disorders among pregnant women.
 Keywords: Thyroid function test, Thyroid dysfunction, T3, T4, TSH, Pregnant women