Prevalence of Thyroid Dysfunction Among  Depression Patients in a Tertiary Care Centre

Kafle, Bikram; Khadka, Bikram; Tiwari, Mukesh

doi:10.31729/jnma.5296

Cited by 13 publications

(16 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6 In another study by Chawanun Charnsil and Sutrak Pilakanta et al, subclinical hyperthyroidism and the remaining 4.3% Some studies have reported a higher prevalence of thyroid dysfunction (26%) than the present study. 13 Another important finding of this study was that there was no significant association between the severity of depressive symptoms and characteristic thyroid dysfunction, which is similar to the findings of Charnsil et al 2 However, this finding is in contrast with a study by Ojha et al, who reported significant correlation that is, more severe the depression higher is the prevalence of thyroid dysfunction. 6 Possible explanations could be differences in diagnostic criteria used for diagnosis and differences in severity of depressive episodes included in both the studies.…”

Section: Discussionsupporting

confidence: 82%

Prevalence and characteristics of Thyroid dysfunction in patients with Depressive Disorders presenting to Tertiary care center- A cross-sectional study

Ganiger¹,

AT²,

Bijjal³

et al. 2022

KJP

View full text Add to dashboard Cite

Background: Thyroid dysfunctions, hypothyroidism and hyperthyroidism, can lead to mood disorders like depression and mania. Conversely, depressive disorders are associated with subtle variations in thyroid hormone levels. Objectives: The objective of the study was to examine the prevalence and characteristics of thyroid dysfunction in patients with Depressive disorders. Methodology: A cross-sectional study was conducted on patients diagnosed with depressive disorders who presented to outpatient and inpatient setting in the psychiatry department. Consecutive sampling method was used till the calculated sample size of 82 patients was reached. Diagnosis of depressive disorder was done as per the International Classification of Diseases, 10 th revision (ICD-10). Hamilton depression rating scale (HAM-D) was administered to assess the severity of depressive symptoms. Thyroid Dysfunction was diagnosed based on the morning (8 AM) serum levels of T3, T4 and TSH levels. Data analysis was done using statistical package for the social sciences (version 24), and results were presented as mean and percentages. Results: Among 82 patients with depression, the prevalence of thyroid dysfunction was 15% (12), and subclinical hypothyroidism was the most common type with prevalence of 11% (9), followed by hypothyroidism. There was no significant association between the severity of depressive episode and the type of thyroid dysfunction (x 2 -14.208, df-9, p-.115). Conclusion: Prevalence of thyroid dysfunction is higher in depressive disorders. Regular monitoring of Thyroid functions tests should be considered during follow up to prevent relapse of symptoms.

show abstract

Section: Discussionsupporting

confidence: 82%

Prevalence and characteristics of Thyroid dysfunction in patients with Depressive Disorders presenting to Tertiary care center- A cross-sectional study

Ganiger¹,

AT²,

Bijjal³

et al. 2022

KJP

View full text Add to dashboard Cite

show abstract

“…Thyroid dysfunction is associated with the occurrence of various neuropsychiatric disorders, including depression (Kafle et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Association between thyroid hormone levels in the acute stage of stroke and risk of poststroke depression: A meta‐analysis

Fu,

Zhao,

et al. 2023

Brain and Behavior

View full text Add to dashboard Cite

BackgroundThyroid hormones have been indicated to be associated with depression, but their relationship with poststroke depression (PSD) remains controversial. Therefore, we performed a meta‐analysis to explore the correlation between thyroid hormone levels in acute stroke and PSD.MethodsWe searched databases for eligible studies. Standard mean differences (SMD) and 95% confidence intervals (CI) were applied to evaluate the association among levels of thyroid hormones, including thyroid‐stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4), in acute stroke patients and the risk of PSD.ResultsA total of 13 studies were included in the analysis. Compared to non‐PSD patients, PSD patients had remarkably lower serum TSH and FT3 levels (TSH: SMD = −0.59, 95%CI = −1.04 to −.15, p = .009; FT3: SMD = −0.40, 95%CI = −.51 to −.30, p = .000) and higher serum FT4 levels (SMD = 0.33, 95%CI = .07–.59, p = .013). Subgroup analysis showed that there may be a more statistically significant association between FT3 and the risk of PSD compared to TSH and FT4.ConclusionsOur results suggested that patients with lower serum TSH and FT3 levels as well as higher serum FT4 levels in the acute stage of stroke may be more susceptible to PSD.

show abstract

“…Additionally, healthcare providers are likely to spend more time on consultation and suggest more examinations for patients with multiple chronic conditions. Third, healthcare providers often prescribe thyroid function and blook lipid tests for patients with mental health disorders, because they all believe thyroid function is strongly associated with emotional problems and patients with thyroid imbalance are more likely to develop lipid problems 34 . Fourth, for patients with long-term treatment of psychotropic drugs, healthcare providers often suggest them to do liver and kidney function tests regularly, because long-term use of medication may cause liver or kidney function damage 35 .…”

Section: Discussionmentioning

confidence: 99%

Associations between mental health disorder and management of physical chronic conditions in China: a pooled cross-sectional analysis

Zhang

Sum

Qin

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Physical non-communicable diseases (NCDs) and mental health disorders are a rapidly increasing health burden in low-and middle-income countries. This study aims to examine the relationships between mental health disorders and cascade of care in managing four common physical NCDs (hypertension, diabetes, dyslipidemia, chronic kidney disease) in China. We utilized two waves of nationally-representative China Health and Retirement Longitudinal Study (CHARLS 2011, 2015) of older adult population aged 45 and above. A series of unadjusted and adjusted mixed-effect logistic regression was applied to evaluate the association between presence of mental health disorder and physical chronic disease awareness, treatment, and control. We found that the odds of dyslipidemia (AOR 1.81, 95% CI 1.36–2.39) and kidney disease awareness (AOR 2.88, 95% CI 2.12–3.92) were higher for individuals with mental chronic conditions, compared to those without mental chronic conditions. The odds of having hypertension treatment was higher for subjects with mental health disorder, compared to those without (AOR 1.32, 95% CI 1.02–1.70). The odds of having physical chronic conditions controlled was not significantly associated with having mental chronic conditions (P > 0.05). These results indicated that adults with mental health disorder have a greater likelihood of awareness of having dyslipidemia and kidney disease, and receiving treatment for hypertension. Strategies to address the growing burden of physical-mental NCDs in China should include efforts to improve management of patients with comorbid health condition and improve access to continual high-quality treatment after the first diagnosis.

show abstract

Prevalence of Thyroid Dysfunction Among Depression Patients in a Tertiary Care Centre

Cited by 13 publications

References 8 publications

Prevalence and characteristics of Thyroid dysfunction in patients with Depressive Disorders presenting to Tertiary care center- A cross-sectional study

Prevalence and characteristics of Thyroid dysfunction in patients with Depressive Disorders presenting to Tertiary care center- A cross-sectional study

Association between thyroid hormone levels in the acute stage of stroke and risk of poststroke depression: A meta‐analysis

Associations between mental health disorder and management of physical chronic conditions in China: a pooled cross-sectional analysis

Contact Info

Product

Resources

About