Prevalence of Type 2 Diabetes among Newly Detected Pulmonary Tuberculosis Patients in China: A Community Based Cohort Study

Wang, Qiuzhen; Ma, Aiguo; Han, Xiuxia; Zhao, Shanliang; Cai, Jing; Ma, Yong; Zhao, Jingcheng; Wang, Yuwen; Dong, Huaifeng; Zhao, Zhenlei; Wei, Lai; Yu, Tao; Chen, Peixue; Schouten, Evert G.; Kok, F.J.; Kapur, Anil

doi:10.1371/journal.pone.0082660

Cited by 64 publications

(76 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association of increasing age with diabetes evident from the study is consistent with past studies conducted in India [17,23,24] and China [25]. Increasing age has been established to be associated with both TB and diabetes through previous studies [26,27].…”

Section: Discussionsupporting

confidence: 91%

Double Trouble: Prevalence and Factors Associated with Tuberculosis and Diabetes Comorbidity in Bangladesh

et al. 2016

View full text Add to dashboard Cite

BackgroundDiabetes among tuberculosis patients increases the risk of tuberculosis treatment failure, death, and development of multidrug-resistant tuberculosis. Yet, there is no data is available in Bangladesh on the prevalence of diabetes among tuberculosis patients. The objective of the current study was to estimate prevalence and identify factors associated with tuberculosis-diabetes co-morbidity among TB patients enrolled in the Directly Observed Treatment, Short course program.MethodsA community based cross-sectional quantitative study was conducted among 1910 tuberculosis patients living in six urban and eleven rural areas among whom Oral Glucose Tolerance Test (those who fasted) and Random Blood Sugar test (those who did not fast) were performed. Besides glucose levels, data on socio-demographic information, family history of diabetes and anthropometric measurements (height and weight) were also collected.ResultAmong the 1910 TB patients who participated in screening for diabetes, 245 (12.8%) were found to have diabetes and 296 (15.5%) to have pre-diabetes. Out of those who had diabetes, 34.7% were newly diagnosed through the current study and 65.3% already knew their status. Among those who were found to have prediabetes, 27 (9.1%) had impaired Fasting Blood Glucose (FBG), 230 (77.7%) had Impaired Glucose Tolerance (IGT), and 39 (13.2%) had both Impaired FBG and IGT. Older age, higher BMI, higher education (secondary level and above), being married, participation in less active work, and family history of diabetes are associated with higher prevalence of diabetes.ConclusionWe observed a higher prevalence of diabetes and pre-diabetes in TB patients than reported previously in Bangladesh among the general population which may challenge TB and diabetes control in Bangladesh. Diabetes diagnosis, treatment and care should be integrated in the National TB Program.

show abstract

Section: Discussionsupporting

confidence: 91%

Double Trouble: Prevalence and Factors Associated with Tuberculosis and Diabetes Comorbidity in Bangladesh

et al. 2016

View full text Add to dashboard Cite

show abstract

“…However, recent studies have shown that DM prevalence among TB cases is variable. It ranges from about 50% reported by some studies in India, about 30% in Mexico, less than 10% in the United States, to even lower values in certain African countries, Spain and China10111213141516. As reported levels of co-morbidity vary highly, National TB Control Programmes (NTPs) will need to decide whether such DM screening is needed.…”

mentioning

confidence: 99%

Screening for diabetes mellitus among tuberculosis patients in Southern Nigeria: a multi-centre implementation study under programme settings

Ekeke¹,

Ukwaja

Chukwu³

et al. 2017

Sci Rep

View full text Add to dashboard Cite

Implementation studies are recommended to assess the feasibility and effectiveness of programmes. In Nigeria, little is known about the burden of diabetes mellitus (DM) among tuberculosis (TB) patients. The objective of this study was to determine screening efficacy, prevalence of DM and determinants of DM among TB patients. We report on a multi-centre implementation study carried-out in 13 health facilities in six States of Southern Nigeria. All newly diagnosed TB patients registered from March to October 2015 were screened for DM using current World Health Organisation guidelines. Overall, 2094 TB patients were evaluated, 196 (9.4%) were found to have DM. The prevalence of newly diagnosed DM was 5.5% (115/2094). DM prevalence varied according to age group; occurring in 2.2% of patients aged ≤ 25 years and 16.9% in patients aged (56–65) years. The additional yield of DM was 59% while the number needed to screen to detect a new case of DM was 18. Factors associated with DM were; age >40 years (aOR2.8, CI 2.1–3.9), rural residence (aOR2.3, 1.6–3.2), private health facility care (aOR2.0, 1.4–2.7), and having an occupation that engages in vigorous activity (aOR0.6, 0.4–0.9). The burden of DM among TB patients is high. Prioritization of DM screening for TB patients is indicated.

show abstract

“…Zheng C et al [14] shows that median age of patients with TB-DM is 49.5 +-11.8, p-value= 0.001. Wang Q et al [15] also shows high proportion of DM as age increases.…”

Section: Proportion Of Dm Among Pulmonary Tuberculosis Patientsmentioning

confidence: 90%

Tuberculosis and Diabetes Mellitus- Not a Sweet Association!

Shukla¹,

Chaudhary²,

Shreenivasa³

2017

jemds

View full text Add to dashboard Cite

BACKGROUNDTuberculosis (TB) continues to be the leading killer among bacterial diseases worldwide. Diabetes is making people three times more susceptible to get active tuberculosis infection. Diabetes Mellitus (DM) is quietly fuelling the spread of tuberculosis. The association between diabetes and TB may be the next challenge for global tuberculosis control worldwide.This study aims to find out proportion of DM among pulmonary tuberculosis patients and proportion of DM among patients with different sputum bacillary load.

show abstract

Prevalence of Type 2 Diabetes among Newly Detected Pulmonary Tuberculosis Patients in China: A Community Based Cohort Study

Cited by 64 publications

References 25 publications

Double Trouble: Prevalence and Factors Associated with Tuberculosis and Diabetes Comorbidity in Bangladesh

Double Trouble: Prevalence and Factors Associated with Tuberculosis and Diabetes Comorbidity in Bangladesh

Screening for diabetes mellitus among tuberculosis patients in Southern Nigeria: a multi-centre implementation study under programme settings

Tuberculosis and Diabetes Mellitus- Not a Sweet Association!

Contact Info

Product

Resources

About