Prevalence of ulcerative stomatitis in arbovirus infections in a Brazilian Northeast population

Abstract

Background Although there are no population-based studies that support an association, there are reports in the literature of mucocutaneous, vesiculobullous and ulcerated lesions in the oral mucosa in cases of arbovirus infection. The aim of this study is to analyze the prevalence of ulcerative stomatitis in individuals affected by arboviruses in a population of the municipality of Arcoverde, Pernambuco, Brazil. Material and Methods 1,003 people living in an area assigned to a Primary Health Care Unit were interviewed. A structured questionnaire was used for data collection, with questions about sociodemographic variables, residence conditions, general health information, as well as information about the general signs and symptoms of arboviruses and specifically about oral lesions. Results Of the 1,003 individuals interviewed, 815 (81.25%) were infected by one or more arboviruses. Of these, 147 (18%) reported ulcerated oral lesions during arbovirus infections. The association between arbovirus infections and the presence of ulcerated oral lesions was statistically significant ( p = 0.000). Conclusions In these cases, the ulcerated lesions on the oral mucosa appear to be associated with arbovirus infection, especially Chikungunya, although the pathophysiological mechanisms are not defined, and the studies are not sufficient to confirm this association. Key words: Arbovirus infections, Dengue, Chikungunya fever, Zika virus.

Might Zika virus‐associated microcephaly's severity impact deciduous tooth eruption and orofacial structures?

“…The condition changes in the human stomatognathic system, such as alterations in the chronology of tooth eruption and the oral structures. However, there is no scientific evidence that verifies the impact of microcephaly's severity on these conditions (Barros et al, 2020; Carvalho et al, 2020; da Silva Sobrinho et al, 2021).…”

Orofacial features in children with microcephaly associated with Zika virus: A scoping review

“…Zika is an arbovirus caused by Zika Virus (ZIKV) and transmitted to humans through hematophagous arthropods (Barros et al., 2020). In 2016, the attention was increased due to the rapid spread of the disease and its repercussions on health and social aspects, especially in newborns' microcephaly cases (Chan et al., 2016; Peiter et al., 2020).…”

Access to information on oral hygiene and mothers' practices of children with microcephaly caused by Zika virus

“…The Northeast region, including the state of Pernambuco was heavily affected. 4 Furthermore, the disease showed an unequal distribution of cases, affecting more severely individuals with lower income and education, and consequently less access to health care. 5 In the following years, there was an explosion of microcephaly cases in the country.…”

“…During the first outbreak of this arboviruses in Brazil between 2015 and 2016, the country even diagnosed 215,319 cases. The Northeast region, including the state of Pernambuco was heavily affected 4 . Furthermore, the disease showed an unequal distribution of cases, affecting more severely individuals with lower income and education, and consequently less access to health care 5…”