Prevalence of Urinary Microalbuminuria in Normal and Hypertensive Koreans and Its Correlation with Blood Pressure Measured by 24 Hours Ambulatory Blood Pressure Monitoring

Park, In soo; Rho, Tae Ho; Park, Ji Won; Jeon, Doo Soo; Yoon, Ho Joong; Choi, Euy Jin; Bang, Byung Ki; Hong, Soon Jo

doi:10.4070/kcj.1994.24.6.834

Cited by 3 publications

(2 citation statements)

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“…Other known cardiovascular risk factors, such as degree of hyperglycemia (1, 20-22), blood pressure (23), hypercholesterolemia (20) and insulin resistance (22) are known to be associated with increasing level of UACR, which were also shown in our results. Although this study was a cross-sectional study, the strength of our study is that we provide degree of coronary artery stenosis and coronary calcium score measured using coronary artery CT, in association with UACR and other known cardiovascular risk factors and biomarker, in a large number of apparently healthy patients.…”

Section: Discussionsupporting

confidence: 84%

Significance of Microalbuminuria in Relation to Subclinical Coronary Atherosclerosis in Asymptomatic Nonhypertensive, Nondiabetic Subjects

et al. 2013

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We aimed to investigate the significance of microalbuminuria and its relationship with subclinical atherosclerosis in nonhypertensive and nondiabetic patients, by using coronary artery computed tomography (CT). A total of 1,318 nonhypertensive and nondiabetic subjects who had taken coronary artery CT and measured spot urine albumin to creatinine ratio (UACR) were evaluated. The atherosclerotic changes of coronary arteries were greater in subjects with microalbuminuria, reflected by coronary artery calcium score (CACS) and significant coronary artery stenosis (CACS ≥ 100 in 15.3% vs 7.6% and stenosis ≥ 50% in 11.5% vs 4.9% of patients with vs without microalbuminuria, P = 0.008 and P = 0.011, respectively). Among various parameters that are known as a risk factor or possible biomarkers of coronary artery disease, presence of microalbuminuria, age and Framingham risk score were significantly related to coronary artery stenosis. Among them the presence of microalbuminuria showed stronger correlation than others to the coronary artery stenosis detected by CT, even after adjusting confounding factors (OR 3.397, 95% confidence interval 1.138 to 10.140, P = 0.028). The presence of microalbuminuria by UACR was significantly associated with presence of coronary artery stenosis ≥ 50% in asymptomatic, nonhypertensive and nondiabetic general population. Our study suggests that the presence of microalbuminuria may imply subclinical coronary artery disease, even in asymptomatic population.

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Section: Discussionsupporting

confidence: 84%

Significance of Microalbuminuria in Relation to Subclinical Coronary Atherosclerosis in Asymptomatic Nonhypertensive, Nondiabetic Subjects

et al. 2013

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“…In regards to the level of dipping in the nighttime BP, for the normal individuals during sleeping, approximately 15% of them had a decrease of BP in comparison with the daytime BP(this is considered normal), and the subjects who had a decrease of such nighttime BP of less than 10% were defined as non-dippers, and the nondipper was reported to be closely associated with the development of cerebral stroke and damage of the target organs. [13][14][15]23) Therefore, the prognostic importance of determining who the non-dippers are among the hypertensive patients has increased. The clinical significance of the nighttime BP dipping level, as divided by the actual sleeping BP, was proven by several studies [24][25][26] that classified the BP based on a diary and it was proven again in the study by MA Eissa et al 27) that classified BP with using actigraphy.…”

Section: Sleep/awake Bp Ratio: Dippermentioning

confidence: 99%

The Usefulness of Electronic Activity Measurement for 24-hour Ambulatory Blood Pressure Monitoring

et al. 2006

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Background and Objectives：The overriding influence of physical activity and the diurnal variation during ambulatory blood pressure monitoring (ABPM) has been well demonstrated. We prospectively evaluated the usefulness of electronic activity monitoring for deriving the actual physical activity and the diurnal variation of ABPM. Subjects and Methods：24-hour ABPM with using an electronic activity monitor was performed on ten normotensive volunteers and fifteen hypertensive subjects. To interpret the ABPM results of the fifteen hypertensive subjects, we obtained the actual awake/sleep periods of every subject with using an electronic activity monitor. Results：The activity values obtained from the ten normotensive volunteers correlated well with the values of the blood pressure (BP) and the heart rate. In the hypertensives, the nocturnal mean BP derived by the actual period was significantly lower than that derived by the arbitrary period (130±16/81±13 mmHg versus 124±13/77±12 mmHg, respectively, p<0.05). The nocturnal BP fall derived by the actual period was significantly larger than that derived by the arbitrary period (14.9±8.7/11.6±7.5 mmHg versus 21.1±8.6/16.2±7.4 mmHg, respectively, p<0.01). Four among the 7 non-dippers determined by the arbitrary period were re-classified as dippers when the actual period was used. One among the 13 hypertensives, as determined by the arbitrary period, was also re-classified as a non-hypertensive. Conclusion：The electronic activity monitor was able to determine the actual activity level. The interpretation of ABPM may be altered by the use of the electronic activity monitor. These results suggest that the accuracy and reproducibility of the 24-hour ABPM will be improved by using an electronic activity monitor. (Korean Circulation J 2006;36:91-98) KEY WORDS：Ambulatory blood pressure monitoring.

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Clinical Implications of Ambulatory and Home Blood Pressure Monitoring

Kim

2010

Korean Circ J

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Because blood pressure (BP) is an ever changing hemodynamic phenomenon, a BP value, once measured at a physician's office (Office BP), is often unrepresentative of an individual's true BP status. Both ambulatory blood pressure monitoring (ABPM) and home blood pressure monitoring (HBPM) provide more accurate and reproducible estimate of BP, and produce stronger predictive ability for cardiovascular outcome than conventional office BP. Two BP measuring techniques, ABPM and HBPM have been widely in clinical use for the detection and management of hypertension. However, they have different advantages and limitations in practice. At present, it has become crucial to understand the characteristics and clinical implications of these BP measuring techniques for those responsible for the care of hypertensive patients.

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Prevalence of Urinary Microalbuminuria in Normal and Hypertensive Koreans and Its Correlation with Blood Pressure Measured by 24 Hours Ambulatory Blood Pressure Monitoring

Cited by 3 publications

References 0 publications

Significance of Microalbuminuria in Relation to Subclinical Coronary Atherosclerosis in Asymptomatic Nonhypertensive, Nondiabetic Subjects

Significance of Microalbuminuria in Relation to Subclinical Coronary Atherosclerosis in Asymptomatic Nonhypertensive, Nondiabetic Subjects

The Usefulness of Electronic Activity Measurement for 24-hour Ambulatory Blood Pressure Monitoring

Clinical Implications of Ambulatory and Home Blood Pressure Monitoring

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