Prevalence, pain management and registration in Internal Medicine units

Muñoz-Alvaredo, Laura; Vallecillo, María López; Pérez, José Luis Alonso; Martín-Gil, Belén; Moreno, María Begoña Prieto; Fernández-Castro, Mercedes

doi:10.1016/j.enfcle.2018.11.002

Cited by 4 publications

(5 citation statements)

References 28 publications

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“…Despite screening and assessment of pain are considered the cornerstone of pain treatment (Angeletti et al, 2018 ), we agree with other authors that pain is still often assessed and documented inadequately (Muñoz‐Alvaredo et al, 2020 ; Plummer et al, 2017 ). Hardly 2 out of 10 patients had pain assessment documented three times a day (i.e.…”

Section: Discussionsupporting

confidence: 87%

“…In spite of being considered one of the key components for the correct management of pain and an indicator of good clinical practice, some authors point out that the nursing record of pain is insufficient and inadequate (Muñoz‐Alvaredo et al, 2020 ). This is not only a barrier to the correct approach to pain, but also makes it difficult to determine the effectiveness of pain management interventions (Plummer et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

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Do we really know if they are in pain? A cross‐sectional study in hospitalised adult patients in Spain

Lorenzo Allegue,

Laredo Velasco,

Recio Vivas

et al. 2023

Nursing Open

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AimsTo describe the prevalence and characteristics of pain in adult hospitalised patients, as well as to analyse the concordance between patient‐reported and recorded pain and its impact on analgesic management.DesignA cross sectional study.MethodsThe study was performed on a sample of 611 patients, from October to December 2017. Data were obtained from patient interviews, review of medical and nursing records and review of electronic prescribing.ResultsThe prevalence of pain at the time of the interview was 36.7%. The median VAS score was 4. 90% of the patients had their pain assessed within the last 24 h; however, concordance between patient‐reported pain and recorded pain in the nursing record was slight.ConclusionPain is still often documented inadequately. Despite the wide use of analgesics, half of the patients with moderate to severe pain do not have adequate pain management. A systematic assessment and recording of pain promotes appropriate analgesic prescription.Implications for the profession and patient careThe findings of our study provide insight into the main gaps in the correct management of pain in hospitalised patients. A systematic assessment and recording of the pain suffered by the patient facilitates its control and allows a better management of the analgesic prescription by the physician. This information could help hospital managers to develop training programmes on pain assessment and on the importance of doctor–nurse collaboration to improve pain management, increasing the quality of care and reducing hospital costs.Reporting methodThe study has adhered to the relevant EQUATOR guidelines, according to The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.

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Section: Discussionsupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Do we really know if they are in pain? A cross‐sectional study in hospitalised adult patients in Spain

Lorenzo Allegue,

Laredo Velasco,

Recio Vivas

et al. 2023

Nursing Open

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“…Reasons for this may include that the standards developed, the clinical practice guidelines, and the majority of the studies carried out in hospital settings, have evaluated the existence of pain in the postoperative period and in cancer patients, and not so much in medical units (Sepúlveda-S anchez et al, 2016). In internal medicine patients are usually elderly, with comorbidities and some of them are long-term suffers which could result in high levels of prevalence of pain (Muñoz-Alvaredo et al, 2018). Because of that, these patients usually have longer average hospital stays and need more Care Plans (Muntinga et al, 2016;Zo€ ega et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

Factors Relating to Nurses’ Knowledge and Attitudes Regarding Pain Management in Inpatients

Fernández-Castro

Martín-Gil

López

et al. 2021

Pain Management Nursing

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“…Chronic pain represents the most frequent condition ( Raffaeli et al, 2021 ). More than 50% of hospitalized patients suffer from chronic pain in Spain and United Kingdom ( Fayaz et al, 2016 ; Muñoz-Alvaredo et al, 2020 ) and 14% have moderate-to-severe disabling chronic pain ( Dueñas et al, 2015 ; Yoshida et al, 2018 ; Mills et al, 2019 ). Therefore, an appropriate pain management by analgesics should be made.…”

Section: Introductionmentioning

confidence: 99%

Pharmacogenetic landscape of pain management variants among Mediterranean populations

Jmel,

Boukhalfa,

Gouiza

et al. 2024

Front. Pharmacol.

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Background:Chronic pain is a major socioeconomic burden in the Mediterranean region. However, we noticed an under-representation of these populations in the pharmacogenetics of pain management studies. In this context, we aimed 1) to decipher the pharmacogenetic variant landscape among Mediterranean populations compared to worldwide populations in order to identify therapeutic biomarkers for personalized pain management and 2) to better understand the biological process of pain management through in silico investigation of pharmacogenes pathways.Materials and Methods:We collected genes and variants implicated in pain response using the Prisma guidelines from literature and PharmGK database. Next, we extracted these genes from genotyping data of 829 individuals. Then, we determined the variant distribution among the studied populations using multivariate (MDS) and admixture analysis with R and STRUCTURE software. We conducted a Chi2 test to compare the interethnic frequencies of the identified variants. We used SNPinfo web server, miRdSNP database to identify miRNA-binding sites. In addition, we investigated the functions of the identified genes and variants using pathway enrichment analysis and annotation tools. Finally, we performed docking analysis to assess the impact of variations on drug interactions.Results:We identified 63 variants implicated in pain management. MDS analysis revealed that Mediterranean populations are genetically similar to Mexican populations and divergent from other populations. STRUCTURE analysis showed that Mediterranean populations are mainly composed of European ancestry. We highlighted differences in the minor allele frequencies of three variants (rs633, rs4680, and rs165728) located in the COMT gene. Moreover, variant annotation revealed ten variants with potential miRNA-binding sites. Finally, protein structure and docking analysis revealed that two missense variants (rs4680 and rs6267) induced a decrease in COMT protein activity and affinity for dopamine.Conclusion:Our findings revealed that Mediterranean populations diverge from other ethnic groups. Furthermore, we emphasize the importance of pain-related pathways and miRNAs to better implement these markers as predictors of analgesic responses in the Mediterranean region.

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Prevalence, pain management and registration in Internal Medicine units

Cited by 4 publications

References 28 publications

Do we really know if they are in pain? A cross‐sectional study in hospitalised adult patients in Spain

Do we really know if they are in pain? A cross‐sectional study in hospitalised adult patients in Spain

Factors Relating to Nurses’ Knowledge and Attitudes Regarding Pain Management in Inpatients

Pharmacogenetic landscape of pain management variants among Mediterranean populations

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