Prevalence, predictors and prognostic significance of microalbuminuria in acute cardiac patients: a single center experience

Valente, Serafina; Lazzeri, Chiara; Chiostri, Marco; Alterini, Bruno; Ognibene, Agostino; Giglioli, Cristina; Pigozzi, Clara; Gensini, Gian Franco

doi:10.1007/s11739-011-0619-2

Cited by 4 publications

(4 citation statements)

References 31 publications

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“…In studies investigating the association of MA with glucose levels, there were conflicting results (22,37,38). Like some of these studies, we were not able to demonstrate any correlation between fasting or postprandial glucose levels and MA in a hypertensive group.…”

Section: Discussioncontrasting

confidence: 87%

Non-Diyabetik Hipertansif Kadinlarda Mikroalbüminüri, Rezistin ve Kardiyometabolik Risk Faktörlerini Etkiler mi?

Ulu¹,

Gürsoy²,

Demirbaş³

et al. 2014

Haseki

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Hipertansiyon, obezite, insülin rezistansı ve lipid seviyeleri kardiyovasküler hastalık için risk faktörleridir. C-reaktif protein, homosistein ile kardiyovasküler risk arasındaki ilişki uzun zamandır tartışılmaktadır. Rezistin ve mikroalbüminürinin diyabetes mellitus, insülin rezistansı ve kardiyovasküler hastalık ile bağlantılı olduğu kabul edilmektedir. Çalışmamızda non-diyabetik hipertansif kadınlarda mikroalbüminüri ile antropometrik ve metabolik parametreler, C-reaktif protein, homosistein ve rezistin ilişkisini araştırmayı planladık. Yöntemler: Otuz yedi mikroalbüminürisi olmayan ile 47 mikroalbüminürisi olan non-diyabetik hipertansif kadın hastayı kapsayan randomize bir çalışma gerçekleştirdik. Gruplarımızda antropometrik ve metabolik parametreleri, C-reaktif protein, homosistein, insülin rezistans indeksi ve rezistin seviyelerini kıyasladık. Bulgular: Mikroalbüminürisi olan hipertansiflerde olmayanlara oranla C-reaktif protein, homosistein, rezistin, insülin seviyeleri ve insülin rezistans indeksi yüksek bulundu (all p<0,05). Sonuç: Non-diyabetik hipertansiflerde mikroalbüminürinin C-reaktif protein, homosistein ve rezistin seviyeleri üzerine etkisi olabileceğini bulduk. Non-diyabetik hipertansif kadınlarda insülin ve insülin rezistansı da mikroalbüminüriden etkilenebileceğini de düşünmekteyiz. (Ha se ki T›p Bül te ni 2014; 52: 172-6) Anahtar Sözcükler: Albüminüri, hipertansiyon, obezite, c-reaktif protein, homosistein, rezistin, kan şekeri, lipidler Abs tract Aim: Hypertension, obesity, insulin resistance and lipid levels are risk factors for cardiovascular disease. The association of cardiovascular risk with C-reactive protein and homocysteine has been debated for decades. Resistin and microalbuminuria are presumed to be associated with diabetes mellitus, insulin resistance and cardiovascular disease. The objective of our study was to investigate the relationship of microalbuminuria with antropometric and metabolic parameters, C-reactive protein, homocyteine and resistin in non-diabetic hypertensive females. Methods: We conducted a randomized study including 37 female non-diabetic hypertensives without microalbuminuria and 47 female non-diabetic hypertensive patients with microalbuminuria. We made comparisons of anthropometric and metabolic parameters, C-reactive protein, homocysteine, insulin resistance index and resistin between the groups. Results: C-reactive protein, homocysteine, resistin, insulin levels and homeostasis model assessment of insulin resistance were higher in hypertensives with microalbuminuria than in hypertensives without microalbuminuria (all p<0.05). Conclusion: We found that microalbuminuria may have an influence on C-reactive protein, homocysteine and resistin levels in non-diabetic hypertensives. We also think that insulin and insulin resistance may also be related with microalbuminuria in nondiabetic hypertensive female patients.

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Section: Discussioncontrasting

confidence: 87%

Non-Diyabetik Hipertansif Kadinlarda Mikroalbüminüri, Rezistin ve Kardiyometabolik Risk Faktörlerini Etkiler mi?

Ulu¹,

Gürsoy²,

Demirbaş³

et al. 2014

Haseki

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“…Micro albuminuria has been extensively evaluated as a cardiac biomarker and in many other conditions. 1,3 A transient increase in the urinary albumin excretion rate has been noted in acute myocardial infarction. This has been attributed to the increased vascular permeability following the inflammatory process in infarction.…”

Section: Introductionmentioning

confidence: 99%

Role of Microalbuminuria as a Predictor of Severity of Coronary Artery Disease - A Prospective Cohort Study

Paul¹

2018

jmscr

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“…Glucose, creatinine and Tn I were measured three times a day during ICCU stay and peak values for each variable were considered. Acute insulin resistance was measured by means of homeostatic model assessment (HOMA) [5,[9][10][11][12]. (Table 1).…”

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confidence: 99%

“…They also exhibited a worse in-hospital glycemic control (as inferred by peak glycemia) and a higher inflammatory activation (as indicated by higher values of hs-CRP, microalbuminuria). These factors are known to be associated with a worse prognosis at short term in STEMI patients [5,6,[10][11][12].…”

mentioning

confidence: 99%

ST-elevation myocardial infarction with preserved ejection fraction: The impact of worsening renal failure

Lazzeri¹,

Valente²,

Chiostri³

et al. 2012

International Journal of Cardiology

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Prevalence, predictors and prognostic significance of microalbuminuria in acute cardiac patients: a single center experience

Abstract: The objective of this study was to prospectively assess the prevalence, predictors and prognostic

Cited by 4 publications

References 31 publications

Non-Diyabetik Hipertansif Kadinlarda Mikroalbüminüri, Rezistin ve Kardiyometabolik Risk Faktörlerini Etkiler mi?

Non-Diyabetik Hipertansif Kadinlarda Mikroalbüminüri, Rezistin ve Kardiyometabolik Risk Faktörlerini Etkiler mi?

Role of Microalbuminuria as a Predictor of Severity of Coronary Artery Disease - A Prospective Cohort Study

ST-elevation myocardial infarction with preserved ejection fraction: The impact of worsening renal failure

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