Prevalence, quality of life and psychosocial function in obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in northern Germany

Grabe, H. J.; Meyer, Christian; Hapke, Ulfert; Rumpf, Hans‐Jürgen; Freyberger, Harald J.; Dilling, Horst; John, Ulrich

doi:10.1007/s004060070017

Cited by 136 publications

(102 citation statements)

References 21 publications

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“…Our findings suggest that OCS without further sub-clinical features is indeed clinically meaningful, both in its own right and in the extremely common presentation with comorbid conditions. The 12-month prevalence of OCD found in this study (0.7%) corresponds to previous studies conducted on the general population, with ranges from 0.3 to 3.0% [2,7,9,23,31,37,50,53,57]. Twelve-month prevalence rates of 0.6 to 4.9% for subthreshold OCD that fulfill some but not all the required DSM-IV criteria of threshold OCD (4.5%) is likewise consistent with previous studies [3,9,22,53].…”

Section: Discussionsupporting

confidence: 55%

“…By demonstrating the impact of OCS, our results added important evidence to previous research on subthreshold OCD. It has been argued that OCD should be defined using less restrictive criteria because subthreshold OCD might better describe the clinical reality of individuals who suffer from this symptomatology [23,52]. Our findings suggest that OCS without further sub-clinical features is indeed clinically meaningful, both in its own right and in the extremely common presentation with comorbid conditions.…”

Section: Discussionmentioning

confidence: 49%

“…To date, only three studies (see Table 1) have examined impairment and health care utilization in relation to subthreshold conditions of OCD, defined as fulfilling at least one but not all core DSM-III-R/IV criteria [9,23] or defined as the presence of obsessive-compulsive symptoms (OCS) according to DSM-IV as well as moderate distress [2]. These studies have found that the 12-month prevalence of subthreshold OCD was more frequent (0.6-4.9%) [3,9,22,53] than that of threshold OCD (0.3-3.0%) [2,7,9,23,31,37,50,53,57] in the general population and that the subthreshold conditions are strongly associated with more comorbidity, poorer functioning at work or in social activities and a greater use of health-care services [2,3,9,22,23].…”

Section: Introductionmentioning

confidence: 99%

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Obsessive–compulsive disorder in the community: 12-month prevalence, comorbidity and impairment

Adam

Meinlschmidt

Gloster³

et al. 2011

Soc Psychiatry Psychiatr Epidemiol

158

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Background Although subthreshold conditions are associated with impairment in numerous disorders, research on obsessive-compulsive disorder (OCD) below the diagnostic threshold of DSM-IV in the general population is limited. Purpose To estimate the DSM-IV 12-month prevalence, comorbidity and impairment of OCD, subthreshold OCD (i.e., fulfilling some but not all core DSM-IV criteria), and obsessive-compulsive symptoms (OCS) (i.e., endorsement of OCS without fulfilling any core DSM-IV criteria) in a general population sample. Methods Data from the German National Health Interview and Examination Survey-Mental Health Supplement (N = 4181, age 18-65 years), based on the standardized diagnostic Munich Composite International Diagnostic Interview. Results The 12-month prevalence of OCD was 0.7%, subthreshold OCD was 4.5%, and OCS was 8.3%. Subjects in all three groups showed higher comorbidity (odds ratios [ORs] C 3.3), compared to those without OCS. The OCD, subthreshold OCD and OCS were all associated with increased odds of substance abuse/dependence-, mood-, anxiety-and somatoform disorders, with especially strong associations with possible psychotic disorder (ORs C 4.1) and bipolar disorders (ORs C 4.7). Participants in all three groups showed higher impairment (ORs C 3.1) and healthcare utilization (ORs C 2.4), compared to those without OCS, even after controlling for covariates. Conclusions Individuals with subthreshold OCD and OCS, not currently captured by DSM-IV OCD criteria, nevertheless show substantial comorbidity, impairment and health-care utilization. This should be taken into account in future conceptualization and classification of OCD and clinical care.

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Section: Discussionsupporting

confidence: 55%

Section: Discussionmentioning

confidence: 49%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Obsessive–compulsive disorder in the community: 12-month prevalence, comorbidity and impairment

Adam

Meinlschmidt

Gloster³

et al. 2011

Soc Psychiatry Psychiatr Epidemiol

158

View full text Add to dashboard Cite

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“…Most rates were found to be higher for women than for men but several studies demonstrated higher rates for men, compared with women (32,34,38). For studies reporting higher female rates, most rates were 1.1 to 1.8 times higher for women than for men, while one study found a female rate that was 14.8 times that of the male rate (77). With regard to GAD, the 1-year and lifetime rates were generally found to be 1.5 to 2 times higher for women, compared with men.…”

Section: Sex-specific Prevalencementioning

confidence: 97%

Prevalence and Incidence Studies of Anxiety Disorders: A Systematic Review of the Literature

et al. 2006

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Objective: To present the results of a systematic review of literature published between 1980 and 2004 reporting findings of the prevalence and incidence of anxiety disorders in the general population.Method: A literature search of epidemiologic studies of anxiety disorders was conducted, using MEDLINE and HealthSTAR databases, canvassing English-language publications. Eligible publications were restricted to studies that examined age ranges covering the adult population. A set of predetermined inclusion and exclusion criteria were used to identify relevant studies. Prevalence and incidence data were extracted and analyzed for heterogeneity.Results: A total of 41 prevalence and 5 incidence studies met eligibility criteria. We found heterogeneity across 1-year and lifetime prevalence rates of all anxiety disorder categories. Pooled 1-year and lifetime prevalence rates for total anxiety disorders were 10.6% and 16.6%. Pooled rates for individual disorders varied widely. Women had generally higher prevalence rates across all anxiety disorder categories, compared with men, but the magnitude of this difference varied. Conclusion:The international prevalence of anxiety disorders varies greatly between published epidemiologic reports. The variability associated with all anxiety disorders is considerably smaller than the variability associated with individual disorders.Women report higher rates of anxiety disorders than men. Several factors were found to be associated with heterogeneity among rates, including diagnostic criteria, diagnostic instrument, sample size, country studied, and response rate. Clinical Implications · Significant heterogeneity in the prevalence of anxiety disorders signals the need for population-specific health policies and planning. · The prevalence of anxiety disorders eclipses the capacity of specialized mental health services. · Anxiety disorders remain prevalent throughout ages 18 to 64 years. Limitations· The observed heterogeneity may be related to environmental or cultural factors associated with the location of each contributing investigation. · Variance owing to methods of diagnosis and measurement account for a limited portion of the observed heterogeneity. · An insufficient number of incidence studies are available to clarify details concerning the onset of symptoms.

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“…Das Aufsuchen professioneller Hilfe als Ausdruck einer bereits so definierten "Krankheit" war die Ausnahme, verzögerte Inanspruchnahme therapeutischer Hilfe aber eher die Regel. Die Tatsache, dass Patienten mit Zwangserkrankungen im Mittel 7-10 Jahre nach dem Auftreten von Zwangssymptomen erstmals therapeutische Hilfe in Anspruch nehmen [12] und zu diesem Zeitpunkt oft schon ein hoher Grad an Chronifizierung [13,14] Der Forschungsbedarf an Studien zur frühen Identifikation von Zwangserkrankungen ist aufgrund mangelnder "Objektivierbarkeit" des tatsächlichen Krankheitsausbruches nicht gedeckt. Die Entwicklung eines Symptominventars, das neben diesen retrospektiv erfassten frühen Auffälligkeiten, ergänzende Informationen der Angehörigen und "objektive" Kriterien der Professionellen enthält, ist notwendig.…”

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2010

Psychiat Prax

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Prevalence, quality of life and psychosocial function in obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in northern Germany

Abstract: Due to different epidemiological characteristics subclinical OCD might represent a syndrome distinct from OCD which is also associated with significant impairments in personal and interpersonal functions and in quality of life.

Cited by 136 publications

References 21 publications

Obsessive–compulsive disorder in the community: 12-month prevalence, comorbidity and impairment

Obsessive–compulsive disorder in the community: 12-month prevalence, comorbidity and impairment

Prevalence and Incidence Studies of Anxiety Disorders: A Systematic Review of the Literature

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