Prevalence, Risk Factors and Comorbidities of Allergic Rhinitis in South Korea: The Fifth Korea National Health and Nutrition Examination Survey

Rhee, Chae Seo; Wee, Jee Hye; Ahn, Jung Yong; Lee, Woo Hyun; Tan, Keng Lu; Ahn, Soyeon; Lee, Ju Hyun; Lee, Chul Hee; Cho, Yang Sun; Park, Kyoung Ho; Lee, Kun Hee; Kim, Kyung Soo; Lee, Ari; Kim, Jeong Whun

doi:10.2500/ajra.2014.28.4040

Cited by 74 publications

(67 citation statements)

References 38 publications

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“…Chronic obstructive pulmonary disorder (COPD) is one of the main causes of mortality in Korea 2. The prevalence of asthma, allergic rhinitis (AR), and rhinosinusitis is also increasing and has become the major health priority in Korea 3456. These preventable chronic respiratory diseases have a major adverse impact on quality of life, disability, and productivity, resulting in an increased socioeconomic burden.…”

Section: Introductionmentioning

confidence: 99%

Burden of Respiratory Disease in Korea: An Observational Study on Allergic Rhinitis, Asthma, COPD, and Rhinosinusitis

Yoo

Ahn²,

Park

et al. 2016

Allergy Asthma Immunol Res

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PurposeThe Asia-Pacific Burden of Respiratory Diseases (APBORD) study is a cross-sectional, observational one which has used a standard protocol to examine the disease and economic burden of allergic rhinitis (AR), asthma, chronic obstructive pulmonary disorder (COPD), and rhinosinusitis across the Asia-Pacific region. Here, we report on symptoms, healthcare resource use, work impairment, and associated costs in Korea.MethodsConsecutive participants aged ≥18 years with a primary diagnosis of asthma, AR, COPD, or rhinosinusitis were enrolled. Participants and their treating physician completed a survey detailing respiratory symptoms, healthcare resource use, and work productivity and activity impairment. Costs included direct medical cost and indirect cost associated with lost work productivity.ResultsThe study enrolled 999 patients. Patients were often diagnosed with multiple respiratory disorders (42.8%), with asthma/AR and AR/rhinosinusitis the most frequently diagnosed combinations. Cough or coughing up phlegm was the primary reason for the medical visit in patients with a primary diagnosis of asthma and COPD, whereas nasal symptoms (watery runny nose, blocked nose, and congestion) were the main reasons in those with AR and rhinosinusitis. The mean annual cost for patients with a respiratory disease was US$8,853 (SD 11,245) per patient. Lost productivity due to presenteeism was the biggest contributor to costs.ConclusionsRespiratory disease has a significant impact on disease burden in Korea. Treatment strategies for preventing lost work productivity could greatly reduce the economic burden of respiratory disease.

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Section: Introductionmentioning

confidence: 99%

Burden of Respiratory Disease in Korea: An Observational Study on Allergic Rhinitis, Asthma, COPD, and Rhinosinusitis

Yoo

Ahn²,

Park

et al. 2016

Allergy Asthma Immunol Res

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“…Recent studies have shown that the ARIA severity classification clearly discriminates among the impact of AR in all domains of quality of life and categorizes the symptom scores (Zicari et al, 2013). The duration and severity of AR are affected by numerous complex factors such as genetics, age, exposure time, exposure amount, and environmental factors Rhee et al, 2014;Portelli et al, 2015). Furthermore, large worldwide variations in the prevalence of AR symptoms have been explained based on these factors.…”

Section: Introductionmentioning

confidence: 99%

Clinical features of allergic rhinitis in children of Shanghai, China

He¹,

Li²,

Chen³

2016

Genet. Mol. Res.

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ABSTRACT. The aims of the current study were to assess the clinical features of allergic rhinitis (AR) in children in Shanghai. Serumspecific IgE (sIgE) tests were performed on samples from patients with AR symptoms from January 2011 to December 2014. A disease-related questionnaire was completed after AR diagnosis. The allergen profile and clinical features of AR were analyzed. In total, 2713 AR patients were enrolled in this study. Dermatophagoides pteronyssinus was found to be the most common offending allergen in the study population. With increasing age, the prevalence of sIgE against inhalant allergens was significantly increased; however, the opposite trend was observed for food allergens. Additionally, the proportion of children with high levels of sIgE against D. pteronyssinus increased with age. Of the AR cases, 8.6% were classified as intermittent mild, 4.2% as persistent mild, 40.5% as intermittent moderate-severe, and 46.7% as persistent moderatesevere. A family history of allergies and a patient history of allergies within 6 months of birth were significantly associated with the duration and severity of AR symptoms. The occurrence of co-morbidities, such as allergic conjunctivitis, cough, and asthma, gradually increased from intermittent mild, persistent mild, and intermittent moderate-severe to persistent moderate-severe. The most frequently used drugs were topical corticosteroids and oral antihistamines, which were used by 86.7 and 79.0% of patients, respectively. These results confirm the adequacy of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines for classifying AR patients, and advance the understanding of clinical features of AR in children in Shanghai, China.

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“…The prevalence of allergic rhinitis (AR) in the general population is increasing and currently estimated to be approximately 10-25% 1,2. Although AR is not associated with a risk of death, the disorder can have a considerable effect on a patient's quality of life.…”

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confidence: 99%

“…Although AR is not associated with a risk of death, the disorder can have a considerable effect on a patient's quality of life. Consideration of comorbid diseases, including asthma, nasal polyp, olfactory dysfunction and chronic rhinosinusitis, results in a tremendous increase in the medical cost for AR treatment, which has come to entail more than just treating the rhinitis itself 1. Among the current treatment options for AR, specific allergen immunotherapy (SIT) is the only medical intervention that modifies fundamental immunologic mechanisms by inducing tolerance, and it can also modify the natural course of the disease.…”

mentioning

confidence: 99%

Prevalence, Risk Factors and Comorbidities of Allergic Rhinitis in South Korea: The Fifth Korea National Health and Nutrition Examination Survey

Abstract: Prevalence, risk factors, and comorbidities of AR were evaluated in the general Korean population, which will contribute to prevention and treatment of AR and its comorbidities in Koreans.

Cited by 74 publications

References 38 publications

Burden of Respiratory Disease in Korea: An Observational Study on Allergic Rhinitis, Asthma, COPD, and Rhinosinusitis

Burden of Respiratory Disease in Korea: An Observational Study on Allergic Rhinitis, Asthma, COPD, and Rhinosinusitis

Clinical features of allergic rhinitis in children of Shanghai, China

Current Specific Immunotherapy for Allergic Rhinitis: Perspectives from Otorhinolaryngologists

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