Prevalence, risk factors, and outcome of hospitalization of neonatal hyperglycemia at a Nigerian health facility

Adeniji, Emmanuel Oluwatosin; Kuti, Bankole Peter; Elusiyan, Jerome Boluwaji Elutayo

doi:10.4103/njcp.njcp_229_19

Cited by 3 publications

(6 citation statements)

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“…Case reports on neonatal hyperglycaemia are limited, particularly from Indonesia. The present study found six international case reports that are summarised in Table II (15)(16)(17)(18)(19)(20) and Table III (4)(5)(6)(7)(8). No definitive guidelines for neonatal hyperglycaemia have been established to date, at least to the best of our knowledge (10).…”

Section: Discussionmentioning

confidence: 86%

“…The lack of a universally accepted definition and blood glucose threshold makes it difficult to determine the prevalence of neonatal hyperglycaemia. However, recent studies conducted over the past 5 years have estimated the incidence to range from 6 to 69% (4)(5)(6)(7)(8). Neonatal hyperglycaemia is associated with negative consequences in extremely preterm and VLBW/ELBW neonates, including sepsis, intracranial haemorrhage, retinopathy of prematurity (ROP), necrotising enterocolitis (NEC), the requirement for ventilator support, growth retardation and increased mortality rates (9,10).…”

Section: Introductionmentioning

confidence: 99%

“…A number of previous studies on neonatal hyperglycaemia have been published in Western countries (4)(5)(6)(7)(8)(15)(16)(17)(18)(19)(20). The majority of the literature on this topic can be found in books rather than clinical articles (21).…”

Section: Introductionmentioning

confidence: 99%

“…The absence of standardised protocols and treatment algorithms emphasises the need for comprehensive research to develop evidence-based guidelines, potentially starting with published case reports. Moreover, neonatal hyperglycaemia is challenging to treat, with numerous reports indicating poor outcomes associated with this condition (4)(5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

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Neonatal hyperglycaemia in extremely preterm and extremely low birth weight infants: A report of a rare case and a review of the literature

Saputri,

Alodia,

Habiburrahman

2024

World Acad Sci J

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Section: Discussionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Neonatal hyperglycaemia in extremely preterm and extremely low birth weight infants: A report of a rare case and a review of the literature

Saputri,

Alodia,

Habiburrahman

2024

World Acad Sci J

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“…This is related to the imperfect function of islet β cells and immature glycogen decomposing enzymes leading to insulin resistance in premature infants. Newborns with asphyxia, infection, and hypothermia are also prone to hyperglycemia [5]. Iatrogenic hyperglycemia is common in intravenous glucose infusion rate ≥ 5.1mg/kg.min [6].…”

Section: Introductionmentioning

confidence: 99%

A Nomogram model for predicting early hyperglycemia in premature infants

Wang,

Xu,

Yin

et al. 2024

Preprint

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BACKGROUND/AIMS: Hyperglycemia in preterm infants is likely to lead to severe complications and higher mortality. Timely identification of hyperglycemia in preterm infants is vital for the prognosis of patients. We developed and validated predictive models for hyperglycemia in preterm infants < 32 weeks of gestational age to aid in the early detection of these patients. METHODS:A retrospective analysis was performed on 460 premature infants to examine the association of various clinical variables with hyperglycemia. We collected data from June 1, 2021, to May 31, 2023. clinical and demographic parameters were analyzed using univariable and multivariable logistic regression analysis(backward method). We constructed a nomogram to assess the risk of hyperglycemia. The model's accuracy was validated using bootstrap resampling (n=500), and the POC curve was used for discrimination analysis to calibrate function and value. Calibration was evaluated via a calibration curve. The model's clinical utility was evaluated through decision curve analysis. RESULTS: Of the 29 potential predictors analyzed in 460 premature infants, the incidence of hyperglycemia was 24.1%. Multivariable logistic regression analysis identified birth weight, invasive ventilation, and Intraventricular hemorrhage as independent risk factors for premature infants with hyperglycemia. The resulting nomogram accurately predicted hyperglycemia risk with an area under the curve of 0.735(95%CI: 0.685-0.786). The bootstrap-validated area under the curve remained at 0.735(95%CI: 0.687-0.785). This model exhibited excellent calibration and demonstrated greater predictive efficacy and clinical utility for hyperglycemia. CONCLUSIONS: We have developed a prediction nomogram of hyperglycemia that can assist clinical treatment decision-making.

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Prevalence and Prognostic Factors of Stress Hyperglycemia in a Pediatric Population with Acute Illness in Greece—A Prospective Observational Study

Korakas

Argyropoulos

Koliou

et al. 2022

JCM

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Background: stress hyperglycemia (SH) is a relatively frequent finding in pediatric patients. The purpose of this prospective observational study was to identify the prevalence of pediatric SH and its associated risk factors in Greece. Methods: A total of 1005 patients without diabetes who were admitted consecutively for acute illness in a Pediatric Emergency Department were included in the study. Medical history, anthropometric measurements, blood glucose levels, and the medication administered were recorded. A questionnaire was distributed to parents regarding medical and perinatal history and sociodemographic characteristics. Results: There were 72 cases of SH on admission (7.2%) and 39 (3.9%) during hospitalization. Mean age was 6.4 years; 50.3% were male. SH on admission was associated with oral corticosteroid therapy (21.1% vs. 4.7%, p < 0.001), inhaled corticosteroids (12.7% vs. 3%, p < 0.001), and inhaled β2-agonists (30.6% vs. 10.7%, p < 0.001). In-hospital hyperglycemia was associated with oral corticosteroids (adjusted OR = 3.32), inhaled corticosteroids (OR = 10.03) and inhaled β2-agonists (OR = 5.01). Children with asthma were 5.58 and 7.86 times more likely to present admission and in-hospital hyperglycemia, respectively. Conclusions: This is the first report of SH prevalence in pediatric patients in Greece. Asthma, corticosteroids, and β2-agonists significantly increase the risk of SH. No parental factors seem to predispose to SH.

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Prevalence, risk factors, and outcome of hospitalization of neonatal hyperglycemia at a Nigerian health facility

Cited by 3 publications

References 0 publications

Neonatal hyperglycaemia in extremely preterm and extremely low birth weight infants: A report of a rare case and a review of the literature

Neonatal hyperglycaemia in extremely preterm and extremely low birth weight infants: A report of a rare case and a review of the literature

A Nomogram model for predicting early hyperglycemia in premature infants

Prevalence and Prognostic Factors of Stress Hyperglycemia in a Pediatric Population with Acute Illness in Greece—A Prospective Observational Study

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