Prevalencia de enfermedad cardiovascular en personas recién diagnosticadas de diabetes mellitus tipo 2

Mata-Cases, Manel; Fernández-Bertolín, Esther; García-Durán, Manuel; Cos-Claramunt, Xavier; Pareja-Rossell, Clara; Pujol‐Ribera, Enriqueta

doi:10.1016/j.gaceta.2008.05.007

Cited by 2 publications

(7 citation statements)

References 16 publications

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“…It is probably attributable to the low incidence of complications related to the bias of survival as those patients who already had cardiovascular disease have been excluded. In these excluded patients, the association was significant (previously published data), but it was only for smoking (33). A more extended follow up with a greater number of events would have conferred significance to the differences.…”

Section: Discussionmentioning

confidence: 56%

“…We excluded 118 patients without any glycaemia measurement before diagnosis so as to be sure that they were at the onset of the disease. Excluded patients were less obese, hypertensive and hypercholesterolaemic (previously published data) (33). In fact, in our cohort, the main reason for diabetes diagnosis was the monitoring of blood samples in the follow up of hypertension and hypercholesterolaemia (32).…”

Section: Discussionmentioning

confidence: 99%

“…In fact, in our cohort, the main reason for diabetes diagnosis was the monitoring of blood samples in the follow up of hypertension and hypercholesterolaemia (32). However, there was the same gender distribution, mean age and HbA1c and smoking prevalence at diagnosis for excluded and included patients (33).…”

Section: Discussionmentioning

confidence: 99%

“…A detailed description of the methodology as well as the characteristics of the patients and the presence of cardiovascular disease at the time of diagnosis has been previously published (32,33).…”

Section: Methodsmentioning

confidence: 99%

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Incidence of complications and mortality in a type 2 diabetes patient cohort study followed up from diagnosis in a primary healthcare centre

Mata-Cases

Prado-Lacueva

Salido-Valencia

et al. 2011

International Journal of Clinical Practice

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Summary Aims: To determine the microvascular and macrovascular complications and mortality incidence rates and to identify the related factors in patients recently diagnosed with type 2 diabetes between 1991 and 2000 and followed until 2006. Methods: Retrospective longitudinal study in a primary healthcare center. Patients without any measure of glycaemia in the 3 years previous to diabetes diagnosis were excluded. Annual incidence rates for microvascular and macrovascular complications and mortality were estimated. Analysis of KaplanMeier survival curves and Cox proportional risk models by gender were done. Results: Of 469 patients [mean age: 60.4 (SD 10.7) years, 53.9% women], 80 died principally of tumoral (38.7%) and cardiovascular (30%) causes. The mean follow‐up period was 8.81 years. (SD 3.21). The complication rates per 1000 patients/year (95% CI) were: microvascular complications 29.11 (22.97–36.38), macrovascular complications 24.10 (19.05–30.08) and mortality 19.23 (15.25–23.93), all of those being significantly greater in males except for cerebrovascular disease. Complications and mortality were associated with age, HbA1c, HDL‐cholesterol, blood pressure and smoking with a different significance for each gender. HbA1c was related to microvascular complications in both sexes and to macrovascular complications only in women. Conclusion: The annual rates for death and complications in a Mediterranean type 2 diabetic patient cohort followed from diagnosis were lower than those published in Anglo‐Saxon countries. Males showed higher death and complication rates except in terms of cerebrovascular disease. Predictors of complication and death were different depending on gender. In terms of mortality, unlike in other studies, only one‐third of the deaths were for cardiovascular causes.

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Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Incidence of complications and mortality in a type 2 diabetes patient cohort study followed up from diagnosis in a primary healthcare centre

Mata-Cases

Prado-Lacueva

Salido-Valencia

et al. 2011

International Journal of Clinical Practice

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“…15,19, 20,28,34,37,43,45,47,52,55,56,59,60,63,65,66]; 3.5-19.6% for CVA (stroke; 16 studies)[15,19, 20,28,34,43,45,47,52,55,56,59,60,63,65,66]; 2.5-13.0% for PAD (15 studies)[15,19, 20,28,34,37,43,45,52,55,56,59,60,65,66]; and 4.3-20.1% for HF (eight studies)…”

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confidence: 99%

Epidemiology and Economic Burden of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Spain: A Systematic Review

et al. 2021

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Introduction: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in people with type 2 diabetes mellitus (T2DM). The objectives of this systematic literature review were to identify and synthesize published data describing the epidemiology and mortality of CVD in the T2DM population and the associated economic burden. Methods: We conducted a systematic review searching the PubMed and MEDES databases from 2009 to 2019 using predefined selection criteria. Peer-reviewed observational studies reporting primary or secondary data on CVD prevalence, incidence, mortality, resource use and costs in patients with T2DM in Spain, written in English and Spanish, were included. Data were tabulated and summarized descriptively. Results: Of 706 articles identified, 52 were included in the review. Most studies were based on data from hospital discharge databases and registries. The reported prevalence of CVD among patients with T2DM ranged from 6.9 to 40.8%. The prevalence of coronary heart disease ranged from 4.7 to 37%, stroke from 3.5 to 19.6%, peripheral artery disease from 2.5 to 13.0%, and heart failure from 4.3 to 20.1%. Inhospital CVD mortality rates ranged from 5.6 to 10.8%. Direct costs due to CVD in hospitalized patients with T2DM were increased ([ 50%) compared with patients without CVD. No studies analysed indirect costs of CVD in patients with T2DM. Conclusions: The burden of CVD among patients with T2DM, combined with the elevated costs of care, highlights the importance of early prevention as part of integrated management of the disease to improve clinical and economic outcomes.

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Prevalencia de enfermedad cardiovascular en personas recién diagnosticadas de diabetes mellitus tipo 2

Abstract: A high prevalence of cardiovascular disease and cardiovascular risk factors at diabetes diagnosis was observed. Age, smoking habit and elevated glycated haemoglobin were the variables related to cardiovascular disease.

Cited by 2 publications

References 16 publications

Incidence of complications and mortality in a type 2 diabetes patient cohort study followed up from diagnosis in a primary healthcare centre

Incidence of complications and mortality in a type 2 diabetes patient cohort study followed up from diagnosis in a primary healthcare centre

Epidemiology and Economic Burden of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Spain: A Systematic Review

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