Prevalencia de enfermedades reumáticas en población adulta en España (estudio EPISER 2016). Objetivos y metodología

Seoane‐Mato, Daniel; Sánchez-Piedra, Carlos; Silva-Fernández, Lucía; Sivera, Francisca; Blanco, Francisco J.; Pérez-Ruiz, Fernando; Juan-Mas, Antonio; Pego-Reigosa, José María; Narváez, Javier; Martí, Neus Quilis; Verdu, R; Antón-Pagés, Fred; Vila, V.; Courel, L. Garrido; Amo, Natividad del Val del; Zudaire, I. Paniagua; Sturchio, Gustavo Añez; Varo, Fermín Medina; Tudela, María del Mar Ruiz; Pérez, Antonio Romero; Ballina, Javier; García, Anahy Brandy; Canales, Dolores Fábregas; Gayá, Teresa Font; Ferrer, Carolina Bordoy; Álvarez, Beatriz González; Hernández, Laura Casas; Reyes, Fátima Álvarez; Sánchez, Mónica Delgado; Dubois, Cristina Martínez; Sánchez-Fernández, Simón; Vargas, Luisa Marena Rojas; Morales, Paula Virginia García; Olivé, Alejandro; Muñoz, P. Rubio; Larrosa, M.; Ricos, Noemí Navarro; Martín, Eduard Graell; Chamizo, E.; Chaparro, Lara Chaves; Herrera, Sara Rojas; Dolset, Jordi Pons; Ostariz, Miguel Ángel Polo; Garrido, Susana Ruiz-Alejos; Macía-Villa, Cristina; Valenciano, Ana Cruz; Gómez, María Luisa González; Valle, Mercedes Morcillo; Sánchez, Deseada Palma; Martínez, María José Moreno; González, Marta Mayor; Buruaga, Joana Atxotegi Sáenz de; Onaindia, Irati Urionagüena; Cáceres, B. A. Blanco; Dı́az-González, Federico; Bustabad, Sagrario

doi:10.1016/j.reuma.2017.06.009

Cited by 69 publications

(20 citation statements)

References 29 publications

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“…The aims, methods and sample characteristics of the EPISER2016 study have been previously described [ 6 , 7 ]. Briefly explained, it is a population-based, multicenter, cross-sectional study to estimate the prevalence of the major rheumatic diseases (RA; SLE; symptomatic osteoartrhritis of the hand, knee, hip, cervical and lumbar spine; fibromyalgia; ankylosing spondylitis; psoriatic arthritis; Sjögren’s syndrome; gout; and symptomatic osteoporotic fracture) in the adult population in Spain.…”

Section: Methodsmentioning

confidence: 99%

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Prevalence of systemic lupus erythematosus in Spain: higher than previously reported in other countries?

Verdu¹,

Pego-Reigosa

Seoane‐Mato

et al. 2020

Rheumatology

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Objectives Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by the Spanish Society of Rheumatology, the prevalence estimate of SLE in the general adult population in Spain has been updated and its association with sociodemographic, anthropometric and lifestyle variables has been explored. Methods Population-based multicentre cross-sectional study, with multistage stratified and cluster random sampling. Participants were contacted by telephone to carry out a questionnaire for the screening of SLE. Investigating rheumatologists evaluated positive results (review of medical records and/or telephone interview, with medical visit if needed) to confirm the diagnosis. To calculate the prevalence and its 95% CI, the sample design was taken into account and weighing was calculated considering age, sex and geographic origin. Multivariate logistic regression models were defined to analyse which sociodemographic, anthropometric and lifestyle variables included in the telephone questionnaire were associated with the presence of SLE. Results 4916 subjects aged 20 years or over were included. 16.52% (812/4916) had a positive screening result for SLE. 12 cases of SLE were detected. The estimated prevalence was 0.21% (95% CI: 0.11, 0.40). SLE was more prevalent in the rural municipalities, with an odds ratio (OR) = 4.041 (95% CI: 1.216, 13.424). Conclusion The estimated prevalence of SLE in Spain is higher than that described in most international epidemiological studies, but lower than that observed in ethnic minorities in the United States or the United Kingdom.

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Section: Methodsmentioning

confidence: 99%

“…Assuming a Poisson distribution, a sample comprising 4000 individuals would enable to obtain a 95% CI of 0.30, 0.77 for a prevalence of 0.5% (expected for RA) and of 0.14–0.54 for a prevalence of 0.3% (expected for psoriatic arthritis). Assuming 20% of missing values, it was considered necessary to include around 5000 individuals [ 6 , 7 ].…”

Section: Methodsmentioning

confidence: 99%

Prevalence of systemic lupus erythematosus in Spain: higher than previously reported in other countries?

Verdu¹,

Pego-Reigosa

Seoane‐Mato

et al. 2020

Rheumatology

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“…The methods and characteristics of the sample of EPISER2016 have been described elsewhere [6,7]. Briefly, the study was a population-based multicenter cross-sectional study that aimed to estimate the prevalence of rheumatic diseases (rheumatoid arthritis; SLE; symptomatic osteoartrhritis of the hand, knee, hip, cervical and lumbar spine; fibromyalgia; ankylosing spondylitis; psoriatic arthritis; Sjögren's syndrome; gout; and symptomatic osteoporotic fracture) in adult population in Spain.…”

Section: Methodsmentioning

confidence: 99%

Higher prevalence of psoriatic arthritis in the adult population in Spain? A population-based cross-sectional study

et al. 2020

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“…It is the most frequent type of inflammatory arthritis in Western countries, with prevalence rates of up to 1% of the adult population and up to 5% of males aged 65 and over. Concerning Spain, a prevalence rate of 2.4% has been recently announced ( 1 ).…”

Section: Introductionmentioning

confidence: 99%

Gout Is Prevalent but Under-Registered Among Patients With Cardiovascular Events: A Field Study

2020

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Objectives: Gout is an independent cardiovascular (CV) risk factor with significant morbidity and mortality. We aimed to estimate the prevalence of gout, characteristics and management in a hospitalized population for CV disease, a topic that remains to be defined. Methods: An observational, descriptive, cross-sectional study was carried out in patients admitted for CV events in the Cardiology, Neurology, and Vascular Surgery units of a tertiary center. Patients were selected following a non-consecutive, systematic sampling. Data about CV disease and gout were obtained from face-to-face interviews and patients' records. Gout diagnosis was established using the 2015 ACR/EULAR clinical classification criteria. The registration rate of gout was assessed by auditing patients' records and hospital discharge reports of CV events from the units of interest in the previous 2 years. To predict the presence of gout, multivariate logistic regression models were built to study the possible explanatory variables. Results: Two hundred and sixty six participants were recruited, predominantly males (69.9%) and Caucasians (96.6%) with a mean age of 68 years. Gout was identified in 40 individuals; thus, the prevalence was 15.0% (95% CI 10.9-19.2%). In 35% of cases, the diagnosis was absent from patients' records. Gout was found in 1.4-2.6% of hospital discharge reports of CV events, also indicating under-registration. The disease was long-standing, but with low reported rates of flares, involved joints, and tophi. At admission, only half of the gout patients were on urate-lowering therapy, being 38.5% of them on serum urate <6 mg/dl. The only independent predictor of gout was the existence of previous hyperuricemia (median serum urate in previous 5 years ≥7 mg/dl), with an odds ratio of 2.9 (95% CI 1.2-7.1); if hyperuricemia is not included in the model, the only independent predictor was chronic kidney disease (odds ratio 3.0; 95% CI 1.4-6.6). Conclusion: Gout is highly prevalent among patients admitted for CV events, with significant lack of awareness and suboptimal management, despite being a well-established independent CV risk factor.

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Prevalencia de enfermedades reumáticas en población adulta en España (estudio EPISER 2016). Objetivos y metodología

Cited by 69 publications

References 29 publications

Prevalence of systemic lupus erythematosus in Spain: higher than previously reported in other countries?

Prevalence of systemic lupus erythematosus in Spain: higher than previously reported in other countries?

Higher prevalence of psoriatic arthritis in the adult population in Spain? A population-based cross-sectional study

Gout Is Prevalent but Under-Registered Among Patients With Cardiovascular Events: A Field Study

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