Prevalencia de esofagitis eosinofílica: estudio multicéntrico en población pediátrica evaluada en 36 centros de gastroenterología de América Latina

Pierre, Reinaldo; Vieira, Mário César; Vázquez, Rodrigo; Ninomiya, Inés; Messere, Gabriela; Daza, Wilson; Dadán, Silvana; Higuera, Michelle; Sifontes, Leida; Harris, Paul; Gana, Juan Cristóbal; Rodríguez, M.; Vasquez, M.; González, Marcelo; Rivera, Juan; Gonzales, Jorge; Angulo, D.; Cetraro, M.D.; Compare, Mónica Del; López, Karolina; Navarro, Dianora; Calva, Roberto; Wagener, Marta; Zablah, Roberto; Carias, Ailim; Calderón, Otto; Vera-Chamorro, José Fernando; Toca, María del Carmen; Dewaele, Maria Rita; Iglesias, Claudio; Delgado, Laura; León, Keira; Hassan, Isaac; Ussher, Federico; Follett, Francisco; Bernedo, Viviana; Grinblat, Victor; Aguero, Nora; Oviedo, César; García, Antonio Guerrero; Salazar, Abel; Coello, Pablo Alonso; Furnes, Raquel; Menchaca, Mario; Fernández, M; Khoury, Abdo; Rojo, Claudia; Fernández, Sonia Fernández; Morao, César

doi:10.1016/j.rgmx.2018.08.001

Cited by 6 publications

(2 citation statements)

References 19 publications

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“…To the Editor, We recently read this interesting article in the journal: Esofagitis eosinofílica: diagnóstico y manejo 1 . After its description, eosinophilic esophagitis (EoE) has become an epidemiological and editorial phenomenon 2 . We would like to highlight several points, including those related to the definition of EoE.…”

Section: Diagnosticando La Esofagitis Eosinofílicamentioning

confidence: 99%

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Diagnosing eosinophilic esophagitis

et al. 2021

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Section: Diagnosticando La Esofagitis Eosinofílicamentioning

confidence: 99%

“…EoE occurs more frequently in urban populations with higher socioeconomic status, which may also be reflected in some countries and sectors of the population in Latin America. The uneven development of the specialty of gastroenterology and digestive endoscopy is also involved 2 .…”

Section: Diagnosticando La Esofagitis Eosinofílicamentioning

confidence: 99%

Diagnosing eosinophilic esophagitis

et al. 2021

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Eosinophilic esophagitis in children: A cross‐sectional study from a tertiary care center

Samanta,

Poddar,

Kumari

et al. 2023

JGH Open

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Background and AimThe prevalence of eosinophilic esophagitis (EoE) is rising in the West. However, data from the Indian subcontinent is limited. In this prospective cross‐sectional study, we estimated the prevalence of EoE among children undergoing elective upper gastrointestinal endoscopy (UGIE).MethodsWe enrolled 200 consecutive children (123 boys, median age 10.25 years [interquartile range 8.25–14.5]) between March 2020 and November 2022 at our center. Clinical characteristics, endoscopic findings, and laboratory parameters were noted. A total of 12 mucosal biopsies (3 each from the middle and lower third of the esophagus, stomach, and duodenum) were obtained. EoE was diagnosed if the peak eosinophil count was ≥15/high‐power field (HPF) in absence of gastric and duodenal eosinophilia.ResultsThe commonest indications for UGIE were gastroesophageal reflux disease‐like symptoms (29%), inflammatory bowel disease (22.5%), celiac disease (15%), and abdominal pain (13%). EoE was detected in seven children, suggesting an overall prevalence of 3.5%. Of the 20 children evaluated for dysphagia, 4 (20%) had EoE. Also, two of three (67%) children presented with food bolus impaction along with dysphagia had EoE. Of the seven children with EoE, three (43%) had bronchial asthma, two (28.5%) had peripheral eosinophilia, and one (14%) had elevated serum IgE. Trachealization and linear furrows were found in 57% and 71% cases, respectively. Four children received high‐dose proton pump inhibitor (PPI) for 12 weeks, two received PPI+ stricture dilatation, and one received systemic steroids. All achieved clinical, endoscopic, and histopathological remission.ConclusionHospital‐based prevalence of EoE among children undergoing elective UGIE was 3.5%. EoE patients had favorable outcomes with PPI.

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