Prevalência de sorotipos e resistência antimicrobiana de cepas invasivas do pneumococo em crianças: análise de 9 anos

Theoretical pneumococcal vaccine coverage: analysis of serotypes isolated from inpatients at a tertiary care hospital

“…The literature on Brazilian strains tends to indicate serotype 14 as the most common. 15 - 19 Usually, serotypes associated with increased mortality include serotypes 3, 6A, 6B, 8, 19F, 23F, and 6C, whereas those associated with decreased mortality include serotypes 23A, 35B, and 35F. 20 In the cases analyzed here, there were no significant differences between the serotype and the occurrence of death.…”

Prevalence of pneumococcal serotypes and resistance to antimicrobial agents in patients with meningitis: ten-year analysis

“…Considering only children aged up to fi ve years, admitted with invasive disease (23.2% with meningitis) from 1999 to 2009, a 5.6% ceftriaxone-resistance rate was found in the same population assessed in this study. 34 The documented resistance rates for both penicillin and ceftriaxone vary depending on factors, such as geographical location, sample size, time and duration of the assessment, patient's age, and nosology. Usually, resistance tends to predominate in children, 23,[31][32][33] especially in those with meningitis, 23,34 with increasing frequency 23,32,34 and intensity 23 over time in the communities not undergoing universal vaccination.…”