Prevelance of vitamin D and B12 deficiency in adolescence

Yetim, Aylin; Tıkız, Ceyhun; Baş, Firdevs

doi:10.5222/j.child.2017.024

Cited by 6 publications

(11 citation statements)

References 27 publications

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“…For this reason, its deficiency is most frequently seen in the periods when the need is not adequately met with nutrients. Frequency of vitamin B12 deficiency in adolescents was reported to be %10.5 in our country (12). In our study, the median age of vitamin B12 deficient group was 13 years, and 27 of 34 patients (80%) were between the ages of 12 and 18 years that, they were in adolescence period likewise that study.…”

Section: Discussionsupporting

confidence: 54%

“…A total of 34 children (9 girls, 25 boys) with vitamin B12 deficiency and 36 healthy controls (17 girls, 19 boys) were analysed in the study. There was no difference between the groups in terms of median age [13 (range, 4-17) vs. 12.5 (range, [5][6][7][8][9][10][11][12][13][14][15][16][17]]. Physical examination was unremarkable in all subjects participated in…”

Section: Resultsmentioning

confidence: 98%

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Evaluation of Kidney Function Parameters in Children with Vitamin B12 Deficiency

Belder¹,

Gökçebay²

2022

Turkish Journal of Pediatric Disease

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Objective: Vitamin B12 is crucial for cell metabolism, deoxyribonucleic acid synthesis and cell proliferation. Hematological and neurological systems are known to be affected in vitamin B12 deficiency. The aim of this study was to research the effects of vitamin B12 deficiency on kidney function parameters.Material and Methods: Thirty-four children with vitamin B12 deficiency and 36 sex and age-matched healthy controls were included in the study. Complete blood count, serum urea, creatinin, vitamin B12, holotranscobalamin, methyl malonic acid, homocysteine, ferritin, folate and estimated glomerular filtration rate were recorded. Additionally, spot urine protein, microalbumin and neutrophil gelatinase-associated lipocalin were measured.Results: Kidney function parameters were normal for childrens that participated the study. Serum kidney function parameters adjusted for age also showed no significant difference between the two groups. No correlation was found between serum vitamin B12 and neutrophil gelatinase-associated lipocalin; however, a negative correlation was detected between neutrophil gelatinase-associated lipocalin and holotranscobalamin (r =-0.24, p =0.045). Holotranscobalamin was substantially lower in the group with vitamin B12 deficiency (p<0.001). Conclusion:No negative influence of B12 deficiency on kidney function was found in non-anemic children.

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Section: Discussionsupporting

confidence: 54%

Section: Resultsmentioning

confidence: 98%

Evaluation of Kidney Function Parameters in Children with Vitamin B12 Deficiency

Belder¹,

Gökçebay²

2022

Turkish Journal of Pediatric Disease

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“…The results of this study were significant due to the high number of participants. In another study conducted by Yetim et al [10] , the rate of vitamin D deficiency in children older than 10 was reported as 56%.…”

Section: Discussionmentioning

confidence: 92%

“…[1] In recent studies conducted in Turkey, the prevalence of vitamin D deficiency has been reported from 16.5% to 89.6% (Table 4). [6][7][8][9][10][11][12][13][14][15][16][17] Among these studies, the highest rate of vitamin D deficiency was found in the study included pubertal children and adolescents. [11] The lowest deficiency rate was shown in a study conducted on children younger than 10 years old.…”

Section: Discussionmentioning

confidence: 99%

“…[2] Similarly, vitamin D deficiency was commonly reported in studies conducted in different regions of Turkey. [6][7][8][9][10] In most studies, vitamin D deficiency prevalence estimates vary due to deficiency definitions, assessed areas, and considered risk factors. Primary causes of vitamin D deficiency are inadequate vitamin D intake by nutrition and insufficient sunlight exposure.…”

Section: Introductionmentioning

confidence: 99%

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Frequency of Vitamin D Deficiency in Children: A Single-Center Cross-Sectional Study in Istanbul

Varkal¹,

Özçetin²,

Kılıç³

2021

Journal of Contemporary Medicine

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Aim: Vitamin D deficiency is highly prevalent among children worldwide. This study aims to assess the frequency of vitamin D deficiency in children and how it varies according to gender, age, and season in Istanbul. Material and Method:The study included 3096 children aged 0-18 admitted to the pediatric outpatient clinic in Istanbul. The serum 25 hydroxyvitamin D concentration was analyzed by the High-Performance Liquid Chromatography method using HPLC systems analyzers, and the results were categorized into four groups: deficiency (<20 ng/mL), insufficiency (20-30 ng/mL), sufficiency (30-100 ng/mL), and toxicity (>100 ng/mL). Descriptive methods, Chi-square, Independent Samples T-Test, ANOVA, and correlation test were used in the statistical analysis of the data.Results: Of children, 52% were girls and 48% boys. The mean serum 25 hydroxyvitamin D concentration was 21.8±15.8 ng/mL, and the frequency of vitamin D deficiency was 53.1%. There was a different distribution of vitamin D status between age groups. Vitamin D deficiency was more common in older children. The frequency of vitamin D deficiency was significantly higher in girls than boys (57.6% versus 48.3%). The mean serum 25 hydroxyvitamin D concentration was significantly lower in winter and spring. A moderate negative correlation was found between age and serum 25 hydroxyvitamin D concentration (correlation coefficient:-0.36). Conclusion:This study showed that female sex, older children, and the winter/spring seasons were significantly associated with a higher frequency of vitamin D deficiency and a lower mean serum 25 hydroxyvitamin D concentration.

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B12 D3 Correlation: Is Oxidative Stress a Common Link?

Javadekar

Joshi²,

Pradhan

et al. 2023

Journal of Pediatric Hematology/Oncology

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Prevelance of vitamin D and B12 deficiency in adolescence

Abstract: Amaç: D vitamininin kas-iskelet sistemi, immun sistem ve daha birçok mekanizma ile; B12 vitamininin ise özel-(1) , beslenme şekli ve besin özelliklerinin değişimi B12 eksikliğine neden olabilmektedir (2) .

Cited by 6 publications

References 27 publications

Evaluation of Kidney Function Parameters in Children with Vitamin B12 Deficiency

Evaluation of Kidney Function Parameters in Children with Vitamin B12 Deficiency

Frequency of Vitamin D Deficiency in Children: A Single-Center Cross-Sectional Study in Istanbul

B12 D3 Correlation: Is Oxidative Stress a Common Link?

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