Prevención de ictus en pacientes con hipertensión arterial: recomendaciones del Grupo de Estudio de Enfermedades Cerebrovasculares de la Sociedad Española de Neurología

Rodríguez‐Yáñez, Manuel; Gómez-Choco, Manuel; López‐Cancio, Elena; Amaro, Sergio; Leciñana, M. Alonso de; Arenillas, Juan F.; Ayo-Martín, Óscar; Freijó, Marimar; Garcia-Pastor, A; Gomis, Meritxell; Martínez-Sánchez, Patricia; Morales, A.; Palacio-Portilla, E.J.; Roquer, Jaume; Segura, Tomás; Serena, Joaquı́n; Vivancos-Mora, J; Fuentes, Blanca

doi:10.1016/j.nrl.2020.04.031

Cited by 8 publications

(3 citation statements)

References 36 publications

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“…10,19,27 The use of β antagonists, calcium channel antagonists, and ACE inhibitors/ARI carry disparate results, with some studies displaying benefit and others no benefit (or high risk) in stroke prevention or adverse outcomes. 16,17,[28][29][30][31] The diuretics are the mainstay of treatment in heart failure and are used as prophylaxis management regimen for stroke. An added list of literature cites use of diuretics in hypertensive patients and favorable outcomes regarding cardiac and cerebral events.…”

Section: Discussionmentioning

confidence: 99%

“…An added list of literature cites use of diuretics in hypertensive patients and favorable outcomes regarding cardiac and cerebral events. [29][30][31] We studied the drug usage of all the mentioned classes of drugs and results indicate no differential drug regimen amongst the controls, TIA, and cerebral vascular disease patients. Hypertension is harbinger of vascular diseases and stroke, with elevated readings resulting in serious complications.…”

Section: Discussionmentioning

confidence: 99%

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The Connotation of Variances in the Risk Predictors, Medications, Homocysteine, and Homocysteine Pathway Gene Polymorphisms with CVA/Stroke

Rizwan¹,

Khan²,

Anjum³

et al. 2020

Global Medical Genetics

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Cerebrovascular accidents (CVAs) are vascular multifactorial, multigenic ailments with intricate genetic, environmental risk influences. The present study aimed to establish affiliation of CVAs/stroke with blood parameters, differences in prescribed drugs consumption, and with differences in homocysteine pathway genes polymorphisms. The participants in study included controls n = 251, transient ischemic attack (TIA) patients n = 16, and stroke cases n = 122, respectively, (total participants, n = 389). The analyzed single nucleotide polymorphisms (SNPs) included C677T(rs1801133), A1298C(rs1801131) of methylene tetrahydrofolate reductase (MTHFR), A2756G(rs1805087) of methyl tetrahydrofolate homocysteine methyltransferase/methionine synthase (MS), and the A192G(rs662) of paraoxonase 1(PON1) genes, all validated by tetra-primer allele refractory mutation system polymerase chain reaction (T-ARMS-PCR). The insertion deletion (I/D; rs4646994) polymorphism in angiotensin converting enzyme (ACE) gene was analyzed using routine PCR. All studied traits were scrutinized through analysis of variance (ANOVA), and later through regression analysis. Through ANOVA and multiple comparison, there was association of CVA with serum homocysteine, cholesterol, and with diastolic blood pressure readings. When data was subjected to regression, serum homocysteine and diastolic blood pressure (significant through ANOVA), as well as two additional traits, high-density lipoproteins (HDL), and rs1801133 MTHFR SNP sustained statistical significance and noteworthy odds in relation to CVA and stroke. The ailments affecting cerebral vasculature are mutifactorial, whereby genes, proteins, and environmental cues all exert cumulative effects enhancing CVA risk. The current study emphasizes that SNPs and variation in circulating biomarkers can be used for screening purposes and for reviewing their effects in stroke/CVA-linked risk progression.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The Connotation of Variances in the Risk Predictors, Medications, Homocysteine, and Homocysteine Pathway Gene Polymorphisms with CVA/Stroke

Rizwan¹,

Khan²,

Anjum³

et al. 2020

Global Medical Genetics

View full text Add to dashboard Cite

show abstract

“…Arterial hypertension is the most frequent modifiable risk factor and the one that contributes most to the onset of this pathology [ 8 ]. The most common physical sequelae of strokes are usually increased spasticity [ 9 ], sudden decrease in strength [ 10 , 11 ], loss of balance and postural control of the trunk and decreased functional gait ability [ 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Use of Virtual Reality and Videogames in the Physiotherapy Treatment of Stroke Patients: A Pilot Randomized Controlled Trial

Peláez-Vélez

Eckert

Gacto-Sánchez

et al. 2023

IJERPH

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A stroke is a neurological condition with a high impact in terms of physical disability in the adult population, requiring specific and effective rehabilitative approaches. Virtual reality (VR), a technological approach in constant evolution, has great applicability in many fields of rehabilitation, including strokes. The aim of this study was to analyze the effects of a traditional neurological physiotherapy-based approach combined with the implementation of a specific VR-based program in the treatment of patients following rehabilitation after a stroke. Participants (n = 24) diagnosed with a stroke in the last six months were randomly allocated into a control group (n = 12) and an experimental group (n = 12). Both groups received one-hour sessions of neurological physiotherapy over 6 weeks, whilst the experimental group was, in addition, supplemented with VR. Patients were assessed through the Daniels and Worthingham Scale, Modified Ashworth Scale, Motor Index, Trunk Control Test, Tinetti Balance Scale, Berg Balance Scale and the Functional Ambulation Classification of the Hospital of Sagunto. Statistically significant improvements were obtained in the experimental group with respect to the control group on the Motricity Index (p = 0.005), Trunk Control Test (p = 0.008), Tinetti Balance Scale (p = 0.004), Berg Balance Scale (p = 0.007) and the Functional Ambulation Classification of the Hospital of Sagunto (p = 0.038). The use of VR in addition to the traditional physiotherapy approach is a useful strategy in the treatment of strokes.

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Risk factors for ischemic stroke

Mortazavi,

Choon Yee

2025

Cardiometabolic Diseases

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Prevención de ictus en pacientes con hipertensión arterial: recomendaciones del Grupo de Estudio de Enfermedades Cerebrovasculares de la Sociedad Española de Neurología

Cited by 8 publications

References 36 publications

The Connotation of Variances in the Risk Predictors, Medications, Homocysteine, and Homocysteine Pathway Gene Polymorphisms with CVA/Stroke

The Connotation of Variances in the Risk Predictors, Medications, Homocysteine, and Homocysteine Pathway Gene Polymorphisms with CVA/Stroke

Use of Virtual Reality and Videogames in the Physiotherapy Treatment of Stroke Patients: A Pilot Randomized Controlled Trial

Risk factors for ischemic stroke

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